1. European repository of explicit criteria of potentially inappropriate medications in old age.
- Author
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Ivanova, Ivana, Elseviers, Monique, Wauters, Maarten, Christiaens, Thierry, and Vander Stichele, Robert
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DRUGS ,MEDICAL databases ,INFORMATION storage & retrieval systems ,MEDICAL history taking ,PHARMACY information services ,SEVERITY of illness index ,MEDICATION therapy management ,ELECTRONIC health records ,INAPPROPRIATE prescribing (Medicine) - Abstract
Aim: Lack of electronic assessment of medication lists in electronic health records is a barrier for more generalized use of potentially inappropriate medications (PIM) lists, designed for older adults. The aim was to construct a European repository of explicit criteria on PIM, suitable for electronic assessment. Methods: PIM description, medication information, clinical information and level of evidence was entered. Criteria with unclear medication specifications were excluded. Too complex criteria were divided for more operable use. Results: We selected three lists: the European Union (7)-PIM (2015), STOPP/START (2014) and Beers criteria (2015). After exclusion and division, from 641 original criteria of the three PIM-lists, a total of 650 criteria were entered (n = 282 from European Union (7)-PIM, n = 201 from Beers and n = 167 from the STOPP/START list). Identification of the medication was possible with the Anatomical Therapeutic Chemical Classification System for practically all criteria, except for 23 (3.5%). From all criteria, 63.9% required only medication-related information. In 55.7% of the criteria, identification of the active substance(s) was the only medication data requirement and 8.2% required additional information (dose, duration, route of administration). From all criteria, 36.1% required clinical information, from which 17.8% requested disease information only, and 18.3% required additional information (indication, history of diseases, laboratory results or severity of diseases). Conclusions: It was feasible to enter most of the original criteria of the three PIM lists into a repository of electronically applicable criteria. In the future, developers of new PIM lists should take into account semantic interoperability and consider the suitability of the criteria for electronic use. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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