1. [Clinicopathological Characteristics of Early-Onset Colorectal Cancer(EOCRC)Cases in Our Hospital].
- Author
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Yanagisawa K, Ikeshima R, Hiraki M, Hata T, Katsuyama S, Shinke G, Kinoshita M, Nomura H, Yanagawa T, Ohshima K, Ohmura Y, Sugimura K, Masuzawa T, Takeda Y, and Murata K
- Subjects
- Male, Female, Humans, Neoplasm Recurrence, Local drug therapy, Chemotherapy, Adjuvant, Hospitals, Europe, Colorectal Neoplasms drug therapy, Colorectal Neoplasms surgery, Colorectal Neoplasms epidemiology
- Abstract
Background: In recent years, the number of colorectal cancer in Europe and the U. S. has been decreasing, but there are increasing reports on the trend of early-onset colorectal cancer(EOCRC), which is a rare population with no established knowledge on its characteristics., Subjects and Methods: Of 3,501 colorectal cancer cases treated at our hospital between April 2011 and December 2021, those aged 39 years and younger were included., Results: There were 32 EOCRC cases, 11 males/21 females. The histological type was tub in 31 cases and por in 1 case. Postoperative adjuvant chemotherapy was administered in 14 patients, and 12 completed the scheduled course. Twenty nine patients underwent R0 resection, of which 6 patients had recurrence and 5 patients died of primary disease. In summary, although EOCRC patients were in good general condition and had a high completion rate of adjuvant chemotherapy, the relapse rate was high, suggesting the need for aggressive adjuvant chemotherapy and careful postoperative surveillance.
- Published
- 2023