1. European and American subgroup C isolates of avian metapneumovirus belong to different genetic lineages.
- Author
-
Toquin D, Guionie O, Jestin V, Zwingelstein F, Allee C, and Eterradossi N
- Subjects
- Amino Acid Sequence, Animals, Ducks, Europe, Genes, Viral, Metapneumovirus classification, Metapneumovirus isolation & purification, Molecular Sequence Data, North America, Phylogeny, Sequence Homology, Amino Acid, Viral Envelope Proteins genetics, Metapneumovirus genetics
- Abstract
The gene encoding the attachment glycoprotein (G) was sequenced in three French isolates of-subgroup C avian metapneumovirus (APV-C) from ducks. With 1771 nt, this gene proved as long as recently published for North-American APV-C isolates from turkeys. The nt sequences of the duck viruses shared 99% identity but proved only 75-83% identical with their North-American counterparts, viruses of both origins encoding 585 amino acid (aa)-long G proteins. Alignments revealed more homogeneity within the European and North-American groups (at least 98 and 79% aa identity, respectively) than between European and North-American viruses (at best 70% a identity), and confirmed the presence of an extracellular divergent domain (positions 302-484) in APV-C G. A phylogenetic analysis demonstrated that North-American and French isolates of APV-C belonged to significantly different genetic lineages, in agreement with the different geographical origin and host species of these viruses.
- Published
- 2006
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