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Abstract: Objective: The aim of the study was to identify the most relevant literature on skills, attitude and behaviour of children and young people towards the use of an automated external defibrillator (AED) and then develop recommendations according to the principles of evidence-based practice. These recommendations were to serve as a basis for educational materials which would ensure that the implementation of AED-training within schools and youth organisations would be a simple process. Methods: A systematic literature search was performed using a specific research question: “Are children of different ages able/willing to use an AED after a training compared to another/no training?”. A guideline development panel meeting was organised to formulate practice guidelines. The panel consisted of experts from different fields (medicine, education and psychology) and representatives of the end users (teachers and youth leaders). Results: The systematic literature search identified five studies concerning AED skills by children and young people, and two studies concerning the attitudes and behaviour of children and young people towards the use of an AED. The guideline development panel carefully examined the available scientific evidence, took into consideration the skills and attitudes of children and young people, including the psychological consequences of managing a potentially life-saving situation and formulated evidence-based recommendations and good practice points. Conclusion: Based on these recommendations, an education programme and new educational materials have been developed by the Belgian Red Cross-Flanders. In this way school staff and youth leaders are properly supported to teach first aid techniques to children and young people (6–18 years). [Copyright &y& Elsevier]