1. Klebsiella pneumoniae Carbapenemase-producing Enterobacteriaceae, Northeast Florida.
- Author
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Halstead DC, Sellen TJ, Adams-Haduch JM, Dossenback DA, Abid J, Doi Y, and Paterson DL
- Subjects
- Adult, Aged, Aged, 80 and over, Bacterial Proteins genetics, Carbapenems metabolism, Drug Resistance, Multiple, Bacterial genetics, Escherichia coli drug effects, Escherichia coli enzymology, Escherichia coli genetics, Escherichia coli Infections epidemiology, Escherichia coli Infections microbiology, Female, Florida epidemiology, Genotype, Humans, Klebsiella pneumoniae drug effects, Klebsiella pneumoniae genetics, Male, Microbial Sensitivity Tests, Middle Aged, Young Adult, beta-Lactamases genetics, Bacterial Proteins metabolism, Disease Outbreaks, Klebsiella Infections epidemiology, Klebsiella Infections microbiology, Klebsiella pneumoniae enzymology, beta-Lactamases metabolism
- Abstract
Background: Since 2001 there have been several reported outbreaks due to carbapenem-resistant Klebsiella pneumoniae (Kp), particularly in the northeastern states., Methods: Carbapenemase-producing Enterobacteriaceae from healthcare facilities in Northeast Florida were phenotypically identified and confirmed using PCR amplification and sequencing of the blaKPC gene., Results: Results from PFGE analysis of these isolates demonstrated possible horizontal spread from two possible "outbreak" strains during the study period., Conclusions: We present the first published cluster of Kp and Escherichia coli (Ec) cases in Florida carrying the KPC-2 or KPC-3 gene.
- Published
- 2009
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