1. Epidemiological analysis of patients with Type 2 diabetes in France.
- Author
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Grimaldi A, Grangé V, Allannic H, Passa P, Rodier M, Cornet P, Duprat I, Duc-Dodon P, Lemaire A, Liard F, and Eschwège E
- Subjects
- Acarbose adverse effects, Adult, Aged, Databases as Topic, Diabetes Mellitus, Type 2 physiopathology, Diabetic Angiopathies epidemiology, Diabetic Nephropathies epidemiology, Diabetic Neuropathies epidemiology, Diabetic Retinopathy epidemiology, Family Practice, Female, France epidemiology, Heart Diseases epidemiology, Humans, Hypoglycemic Agents adverse effects, Longitudinal Studies, Male, Middle Aged, Acarbose therapeutic use, Diabetes Mellitus, Type 2 drug therapy, Diabetes Mellitus, Type 2 epidemiology, Hypoglycemic Agents therapeutic use
- Abstract
This paper presents the baseline epidemiological data from 5548 patients with type 2 diabetes enrolled in a French observational study that aims to examine the safety, tolerability and use of acarbose as prescribed by general practitioners (GPs). Patients were recruited and monitored by a representative sample of GPs. Recruitment did not depend on a patient's suitability for acarbose treatment. The data revealed that the mean age of the patient population was 63 years, and that more than 50% of patients were over 65 years old. The population was markedly overweight [mean body mass index(BMI): males, 28.4 kg/m(2); females, 29.1 kg/m(2)] and the mean duration of diabetes was 10 (+/-7.3) years. Over 37% of patients had at least one diabetic complication, and the frequency of complications increased with both age and the duration of diabetes. The most frequently reported complications were cardiac (17.8%), vascular (14.5%) and ocular (12%). At recruitment, almost 90% of patients were being treated with oral antidiabetic agents (OADs). Sulphonylureas (74%) and biguanides (50%) were the most commonly prescribed agents. Acarbose was used to treat 17% of patients and 1% were receiving insulin. GPs set glycaemic treatment goals for 44% of patients in the study. Fasting glycaemia was the primary goal for 37% of the total study population, and HbA(1c) levels for 21% of patients. Postprandial glycaemia was generally given as a secondary or tertiary goal. In conclusion, this study provides the most up-to-date epidemiological data for patients with type 2 diabetes in France.
- Published
- 2000
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