34 results on '"Gerbaud, Laurent"'
Search Results
2. Highlighting the impact of social relationships on the propagation of respiratory viruses using percolation theory.
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Mathiot, Jean-François, Gerbaud, Laurent, and Breton, Vincent
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PERCOLATION theory , *SOCIAL networks , *COVID-19 pandemic , *SOCIAL interaction , *PERCOLATION , *EPIDEMICS - Abstract
We develop a site-bond percolation model, called PERCOVID, in order to describe the time evolution of all epidemics propagating through respiratory tract or by skin contacts in human populations. This model is based on a network of social relationships representing interconnected households experiencing governmental non-pharmaceutical interventions. As a very first testing ground, we apply our model to the understanding of the dynamics of the COVID-19 pandemic in France from December 2019 up to December 2021. Our model shows the impact of lockdowns and curfews, as well as the influence of the progressive vaccination campaign in order to keep COVID-19 pandemic under the percolation threshold. We illustrate the role played by social interactions by comparing two typical scenarios with low or high strengths of social relationships as compared to France during the first wave in March 2020. We investigate finally the role played by the α and δ variants in the evolution of the epidemic in France till autumn 2021, paying particular attention to the essential role played by the vaccination. Our model predicts that the rise of the epidemic observed in July and August 2021 would not result in a new major epidemic wave in France. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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3. The Early Impact of the COVID-19 Lockdown on Stress and Addictive Behaviors in an Alcohol-Consuming Student Population in France.
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Flaudias, Valentin, Zerhouni, Oulmann, Pereira, Bruno, Cherpitel, Cheryl J., Boudesseul, Jordane, de Chazeron, Ingrid, Romo, Lucia, Guillaume, Sébastien, Samalin, Ludovic, Cabe, Julien, Bègue, Laurent, Gerbaud, Laurent, Rolland, Benjamin, Llorca, Pierre-Michel, Naassila, Mickael, and Brousse, Georges
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COMPULSIVE behavior ,SUBSTANCE abuse ,COVID-19 ,STAY-at-home orders ,COVID-19 pandemic - Abstract
Background: This study evaluated factors linked with perceived stress related to the COVID-19 pandemic and lockdown and addictive behaviors prior to and during lockdown in a sample of students who indicated engaging in alcohol consumption behaviors before lockdown. Methods: Cross-sectional study. French students from four universities participated in this study, and 2,760 students reported alcohol use. During the first week of lockdown, students reported their perceived levels of stress regarding COVID-19. Substance use and addictive behaviors were reported before and during lockdown, and media exposure, demographical, living conditions, and environmental stressors were reported during lockdown. Results: Women reported greater levels of stress (95% CI: 1.18 to 1.93, p < 0.001). Highly-stressed students also report less social support (95% CI: −1.04 to −0.39, p < 0.001) and were more likely to worry about the lockdown (95% CI: 0.27 to −0.65, p < 0.001). Alcohol-related problemswere more prevalent among the most stressed students (95% CI: 0.02 to 0.09, p = 0.004) as well as eating problems (95% CI: 0.04 to 0.36, p = 0.016) and problematic internet use (95% CI, 0.06 to 0.14, p < 0.001). Students reporting the highest levels of stress also indicated more compulsive eating during the previous seven days (95% CI, 0.21 to 1.19, p = 0.005). Conclusions: The level of stress was strongly related to four categories of variables: (i) intrinsic characteristics, (ii) addictive behaviors before lockdown, (iii) lockdown-specific conditions, and (iv) addictive behaviors during the lockdown. Several variables linked to COVID-19 were not directly linked with perceived stress, while perceived stress was found to correlate with daily life organization-related uncertainty and anticipated consequences of lockdown. Importantly, social support seems to be a protective factor on high level of stress. [ABSTRACT FROM AUTHOR]
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- 2021
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4. Sizing method by optimization with energy management – Application to electrical hybrid train.
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Poline, Marie, Gerbaud, Laurent, Pouget, Julien, Chauvet, Frédéric, and Castaing, Ali
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INDUSTRIAL efficiency , *ENERGY storage , *ELECTRIC potential - Abstract
In France, most of the trains are electrical and some are fed by 1500 V DC voltage. When a train is traveling, the power consumption creates a voltage drop. Therefore, below a certain limit, the train has to slow down its speed. This limitation prevents the increase of traffic in some area that needs an electric reinforcement. This paper proposes to use embedded storage systems to support the voltage of the catenary. The main issue is how to size such an energy storage system? In this way, several aspects (e.g.: the energy management strategy) have to be taken into account. The paper deals with an optimization-based sizing method for the embedded energy storage systems. The proposed method takes into account the energy management strategy in the sizing by optimization. A comparison is made between the use of batteries or supercapacitors. [ABSTRACT FROM AUTHOR]
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- 2019
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5. Validation of the French version of the LEIPAD in community-dwelling people aged 80 years and above.
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Jalenques, Isabelle, Guiguet-Auclair, Candy, Gerbaud, Laurent, Rachez, Chloé, and Rondepierre, Fabien
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CRONBACH'S alpha ,OLDER people ,QUALITY of life - Abstract
Background: Few studies have addressed health-related quality of life in community-dwelling individuals aged 80 years and above and very few self-assessment quality of life questionnaires have been formally validated in these populations. This study aimed to validate a French version of the LEIPAD, a self-administered questionnaire assessing the health-related quality of life of people aged 80 years and over. Method: A cross-sectional study of people aged 80 years and over living at home in France was conducted. All subjects recruited were sent a letter explaining the study and requesting their consent to take part. Those who accepted then received the questionnaires, including the LEIPAD, which assesses health-related quality of life in the subjects aged 65 years and above. We assessed its psychometric properties: data completeness, score distribution, floor and ceiling effects, internal consistency, item-total correlations, inter-scale correlations, reliability and convergent validity with the Medical Outcome Study Short-Form 36 (SF-36). Results: The results obtained from 184 older people (mean age of 83.9 years, standard deviation 3.3) showed very good acceptability (missing data between 1.1% and 11.4% for LEIPAD scales) Factor analysis of the instrument confirmed the multi-dimensional structure in seven independent scales similar to the original version. Good internal consistency (Cronbach’s alpha ranging from 0.68 to 0.87) and strong test-retest reliability of the LEIPAD scales (intraclass correlation coefficients ranging from 0.77 to 0.95) were found. Convergent validity with the SF-36 showed moderate to strong correlations, consistent with the hypotheses stated. Conclusions: The validation of this specific questionnaire will make it possible to investigate individually the health-related quality of life of French older people living at home and will enable French-speaking investigators to contribute to national and international research projects. [ABSTRACT FROM AUTHOR]
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- 2019
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6. Occupational status as a determinant of mental health inequities in French young people: is fairness needed? Results of a cross-sectional multicentre observational survey.
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Blanquet, Marie, Labbe-Lobertreau, Emilie, Sass, Catherine, Berger, Dominique, and Gerbaud, Laurent
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MENTAL health ,AGE distribution ,EMPLOYMENT ,HEALTH services accessibility ,SCIENTIFIC observation ,QUESTIONNAIRES ,SELF-perception ,SEX distribution ,SOCIAL case work ,SURVEYS ,EDUCATIONAL attainment ,CROSS-sectional method ,DESCRIPTIVE statistics ,PSYCHOLOGY - Abstract
Background: Employment conditions are associated with health inequities. In 2013, French young people had the highest unemployment rate and among those who worked as salaried workers most of them had temporary job. The purpose of the study was to assess mental health state of French young people through the prism of their occupational status and to measure whether occupational status is a determinant of health inequities. Methods: A cross-sectional multicentre observational survey was performed in June and July 2010 in 115 French Local Social Centres and 74 Health Examination Centres, who were available to participate. The survey was based on an anonymous self-administrated questionnaire delivered by social workers or healthcare professionals to young people age from 16 to 25 years old. The questionnaire was composed of 54 items. Several health outcomes were measured: self-perceived health, mental health, addictions and to be victim of violence. The association of occupational status and mental health was assessed by adjusting results on age and gender and by introducing other explanatory variables such as social deprivation. Results: A total of 4282 young people completed the questionnaire, a response rate of 83%, 1866 men and 2378 women, sex-ratio 0.79. French young people having a non-working occupational status or a non-permanent working status were more exposed to poor self-perceived health, poor mental health, addictions and violence. To be at school particularly secondary school was a protective factor for addiction. Conclusions: Occupational status of French young people was a determinant of mental health inequities. Young people not at work and not studying reported greater vulnerability and should be targeted therefore by appropriate and specific social and medical services. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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7. Impact of age on care pathways of people living with HIV followed up in hospital.
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Jacomet, Christine, Berland, Pauline, Guiguet, Marguerite, Simon, Anne, Rey, David, Arvieux, Cédric, Pugliese, Pascal, and Gerbaud, Laurent
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HIV infections ,THERAPEUTICS ,AGE distribution ,CHI-squared test ,CONFIDENCE intervals ,FISHER exact test ,HIV-positive persons ,PATIENT aftercare ,OUTPATIENT services in hospitals ,INSURANCE ,MEDICAL cooperation ,MEDICAL protocols ,MEDICAL referrals ,MEDICAL specialties & specialists ,PROBABILITY theory ,QUESTIONNAIRES ,RESEARCH ,RESEARCH funding ,SELF-evaluation ,T-test (Statistics) ,COMORBIDITY ,DISCLOSURE ,SOCIOECONOMIC factors ,REFUSAL to treat ,CROSS-sectional method ,DATA analysis software ,DESCRIPTIVE statistics ,ODDS ratio ,MIXED infections - Abstract
The aging population of people living with human immunodeficiency virus (HIV) (PLWH) is exposed to a widening spectrum of non-AIDS-defining diseases. Thus, our objective was to compare the health care offered to PLWH according to age. We conducted a multicenter cross-sectional study on PLWH who consulted at one of 59 French HIV reference centers from 15th to 19th October 2012. Using our survey questionnaires, PLWH self-reported the medical care they received, whether or not tied to HIV infection monitoring, during the previous year. A total of 650 PLWH participated in the survey (median age 48 years, Interquartile range (IQR) 40–54), of which 95 were aged 60 years or over (14.5%). Compared to younger PLWH, 60-and-over PLWH were more often under complementary health insurance cover and less socially deprived based on the French EPICES (Evaluation of Precarity and Inequalities in Health Examination Centers) score. The elderly PLWH presented more comorbidities and less coinfections with hepatitis viruses. During health care, therapeutic education was less often offered to older PLWH (14% vs. 26%,p = .01), but this difference was mainly explained by sociodemographic factors and clinical status. Over the previous 6 months, 74% of PLWH who were followed up in hospital had also consulted another doctor, with a mean of 3.75 consultations (±4.18) without difference between age groups. After adjustment for sociodemographic factors and comorbidities, PLWH over 60 years were more likely to have consulted medical specialists as outpatients in the last 6 months (odds ratio [OR] = 2.63 [1.11–6.20]). Whatever their age, 13% of PLWH had been refused care on disclosure of their HIV status, and 27% of PLWH still did not disclose their HIV status to some caregivers. Coordinated health care throughout patients’ lives is crucial, as health-care pathways evolve toward outpatient care as the patients get older. [ABSTRACT FROM PUBLISHER]
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- 2017
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8. Metabolic syndrome and social deprivation: results of a French observational multicentre survey.
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Blanquet, Marie, Debost-Legrand, Anne, Gerbaud, Laurent, de La Celle, Catherine, Brigand, Alain, Mioche, Laurence, Sass, Catherine, Hazart, Juliette, and Aw, Alhassane
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SOCIAL psychology ,METABOLIC syndrome diagnosis ,FRENCH people ,DISEASE prevalence ,HEALTH surveys ,DATA extraction ,SCIENTIFIC observation ,DISEASES ,HYPERTENSION epidemiology ,COMPARATIVE studies ,HYPERLIPIDEMIA ,RESEARCH methodology ,MEDICAL cooperation ,OBESITY ,PRIMARY health care ,RESEARCH ,SOCIAL classes ,EVALUATION research ,METABOLIC syndrome ,HEALTH equity ,AT-risk people ,CROSS-sectional method ,WAIST circumference - Abstract
Background: Deprivation, a process that prevents people to assume their social responsibilities, is a main cause of inequalities in health. Metabolic syndrome has a growing prevalence in France.Objectives: To assess the association between deprivation and the metabolic syndrome and to identify the most relevant waist circumference cut-off point.Methods: A cross-sectional multicentre study was carried out of data extracted from health examination centres of two French areas in 2008. The harmonized definition of the metabolic syndrome contained five criteria with two thresholds for waist circumference. Deprivation was calculated by the Evaluation of Deprivation and Inequalities in Health Examination Centres score (EPICES). Eligible patients were at least 16 years old. The methodology of time to event analysis was used on patients having two criteria to identify the most relevant waist circumference threshold, taking waist circumference as event and computing it as a continuous variable. The median corresponded to the waist circumference threshold for which half of the patients switched from two to three criteria and so metabolic syndrome.Results: Of the 32374 persons included in the study, 39.4% were socially deprived. The prevalence of the metabolic syndrome varied from 16.3% to 22.2% in the overall sample depending on the published waist circumference thresholds chosen. Deprivation was an independent factor associated with the metabolic syndrome. The cut-off point for waist circumference was between 95 and 99 cm for men and 88 and 97 cm for women.Conclusion: Deprivation is associated with a higher prevalence of the metabolic syndrome. The most relevant threshold for waist circumference could be 94 cm for men and 88 cm for women. [ABSTRACT FROM AUTHOR]- Published
- 2016
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9. A quality indicator can be biased by intra-hospital heterogeneity: the case for quality of patient record keeping in France.
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Lelong, Audrey, Leger, Stéphanie, Vendittelli, Françoise, Blanquet, Marie, Cong-Tri Thuong, Belgacem, Bénédicte, and Gerbaud, Laurent
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ACADEMIC medical centers ,CLINICAL medicine ,CONFIDENCE intervals ,DATABASES ,HOSPITALS ,MEDICAL databases ,INFORMATION storage & retrieval systems ,MEDICAL records ,RESEARCH funding ,STATISTICAL sampling ,STATISTICS ,ORGANIZATIONAL structure ,KEY performance indicators (Management) ,INTER-observer reliability ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background: Since 2008, French health institutions providing medical, surgical and obstetrical care are assessed on the basis of a set of quality indicators. The French National Authority for Health developed a survey design in which 80 records are randomly selected from each institution. The main aim was to assess the effects of internal heterogeneity of a hospital that comprises several units. The survey method is based on the hypothesis of intra-institution homogeneity, which overlooks the fact that in wide hospitals homogeneity is related to departments and thus leads to overall intra-hospital heterogeneity. Methods: Simulated databases were created to modelise the heterogeneity of our hospital and computed to assess the reliance of indicator measurement. We used real data from a large teaching hospital having internal heterogeneity related to each department. Results: Variance under heterogeneity was greater than under homogeneity (3-to 18-fold) leading to an increased size of the confidence interval (CI) (at 95%) from 9 (given Haute Autorité de Santé sources) to 22 (for greatest internal heterogeneity). Conclusions: The variations in a quality indicator can be explained by intra-institution heterogeneity and are not related to changes in the quality policy of the hospitals and may lead to errors in terms of pay for performance. [ABSTRACT FROM AUTHOR]
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- 2015
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10. A new reliable index to measure individual deprivation: the EPICES score.
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Labbe, Emilie, Blanquet, Marie, Gerbaud, Laurent, Poirier, Gilles, Sass, Catherine, Vendittelli, Françoise, and Moulin, Jean-Jacques
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CONFIDENCE intervals ,STATISTICAL correlation ,EXPERIMENTAL design ,HEALTH services accessibility ,HEALTH status indicators ,RESEARCH methodology ,MORTALITY ,RESEARCH funding ,RESEARCH methodology evaluation ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background: Deprivation is associated with inequalities in health care and higher morbidity and mortality. To assess the reliability of a new individual deprivation score, the EPICES score and to analyse the association between the Townsend index, the Carstairs index and the EPICES score and causes of death in one French administrative region. Methods: Eligible patients were 16 years old or more who had come for consultation in Health Examination Centres of the French administrative region of Nord-Pas-de-Calais. An ecological study was performed between 2002 and 2007 in the 392 districts of this administrative region. The EPICES score was compared with the Townsend and the Carstairs indices. These three measurements of deprivation were compared with social characteristics, indicators of morbidity, health-care use and mortality and specific causes of death. The Pearson correlation coefficients were calculated to assess the reliability of the EPICES score. The association between deprivation and mortality was assessed by comparison of the standardized mortality ratio (SMR) between the most and least deprived districts. Results: The EPICES score was strongly correlated with the Townsend and Carstairs indices and with the health indicators measured. SMR increased with deprivation and the higher the deprivation the higher the SMR for all-cause mortality, premature and avoidable deaths and for most specific causes of death. Conclusion: The individual deprivation EPICES score is reliable. Deprivation was related to excess death rate, which clearly indicates that deprivation is a determinant factor that should be considered systematically by health policy makers and health-care providers. [ABSTRACT FROM AUTHOR]
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- 2015
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11. Perception of Antiretroviral Generic Medicines: One-Day Survey of HIV-Infected Patients and Their Physicians in France.
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Jacomet, Christine, Allavena, Clotilde, Peyrol, Fleur, Pereira, Bruno, Joubert, Laurence Morand, Bagheri, Haleh, Cotte, Laurent, Garaffo, Rodolphe, Gerbaud, Laurent, and Dellamonica, Pierre
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GENERIC drugs ,ANTIRETROVIRAL agents ,HIV-positive persons ,PHYSICIANS ,CROSS-sectional method - Abstract
Background: In the interest of cost effectiveness, switching antiretroviral brand name medications to generics is recommended in France since 2013. The study objective was to evaluate the perception of generics per se and antiretroviral generics in HIV-infected patients and their hospital physicians Methods and Findings: 556 out of 703 (79%) adult HIV+ outpatients and 116 physicians in 33 clinics were included in a multicentric cross-sectional survey performed in September 2013. Patients completed a self-questionnaire on their perception and acceptability of generics. Physicians completed a questionnaire on their acceptability of switching antiretroviral to generic. Socio-demographic data, medical history and HIV history were collected. Among the 556 patients with a median HIV duration of 13 years, 77% were France native, 59% in active employment, 100% covered by social insurance, 95% on antiretroviral therapy. Seventy-six percent of the patients accepted generics and 55% trusted them overall. Antiretroviral generics were accepted by 44% of them but only by 17% if the pill burden was going to increase. The factor significantly associated with acceptability of antiretroviral generics was acceptance of generics per se (p<0.001). Among the 116 physicians following a median of 100 HIV-patients/year, 75% would prescribe generics, dropping to 26% if the combo had to be broken. Factors significantly associated with willingness to prescribe antiretroviral generics were the absence of concern regarding the chemical entity (OR = 0.33), being aware that the patient would accept generics for other pathologies (OR = 2.04) and would accept antiretroviral generics (OR = 1.94). No factor related to sociodemographic conditions, HIV status or comorbidities was associated with the acceptability of antiretroviral generics. Conclusions: Acceptability of antiretroviral generics in this French population was mostly dictated by the patient’s and physician’s knowledge and use of generics overall. It should be improved with an efficient information of both patients and physicians. [ABSTRACT FROM AUTHOR]
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- 2015
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12. Measuring preventive procedures by French GPs: an observational survey.
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Blanquet, Marie, Gerbaud, Laurent, Noirfalise, Chantal, Llorca, Pierre Michel, Campagne, Claude, and Malaval, Jacques
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FAMILY medicine ,GENERAL practitioners ,PROFESSIONAL orientations ,MEDICAL software - Abstract
Background Prevention has become a legal obligation for French GPs, since a law was passed in March 2002. Aim Measurement and analysis of preventive procedures performed by French GPs. Design of study Observational survey. Setting GP surgeries in Puy-de-Dôme, France. Method Doctors completed a questionnaire about their socioprofessional characteristics, and a researcher completed another questionnaire about preventive procedures performed on the last 15 patients seen by each GP. Twenty preventive services were evaluated and, for each service, medical records, targets, and objectives were defined according to the national preventive care guidelines. The gap between guidelines and practice was explained by doctor characteristics. Statistical analyses were performed using Χ² and logistic regression. Results Representative samples of 179 doctors and 2453 medical records were randomised. Four preventive services were performed in more than 75% of cases, and the gap was explained by the salaried job the doctors had. Ten preventive services were performed in 25% to 75% of cases and the gap was explained by the medical software used. The six remaining services were performed in less than 25% of cases and no explanatory variable was identified. Conclusion Sixteen preventive procedures were insufficiently performed. The more a preventive service is performed the more the gap will be explained by GPs' socioprofessional characteristics. The gap for a preventive procedure performed in 25% to 75% of cases was mainly explained by management of the medical records. A nationwide policy to improve prevention performance in general practice seems to be essential. [ABSTRACT FROM AUTHOR]
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- 2011
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13. Risk Factors for Ectopic Pregnancy: A Comprehensive Analysis Based on a Large Case-Control, Population-based Study in France.
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Bouyer, Jean, Coste, Joël, Shojaei, Taraneh, Pouly, Jean-Luc, Fernandez, Hervé, Gerbaud, Laurent, and Job-Spira, Nadine
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ECTOPIC pregnancy ,DISEASE risk factors ,SMOKING ,INFERTILITY ,INTRAUTERINE contraceptives ,ABORTION - Abstract
This case-control study was associated with a regional register of ectopic pregnancy between 1993 and 2000 in France. It included 803 cases of ectopic pregnancy and 1,683 deliveries and was powerful enough to investigate all ectopic pregnancy risk factors. The main risk factors were infectious history (adjusted attributable risk = 0.33; adjusted odds ratio for previous pelvic infectious disease = 3.4, 95% percent confidence interval (CI): 2.4, 5.0) and smoking (adjusted attributable risk = 0.35; adjusted odds ratio = 3.9, 95% CI: 2.6, 5.9 for >20 cigarettes/day vs. women who had never smoked). The other risk factors were age (associated per se with a risk of ectopic pregnancy), prior spontaneous abortions, history of infertility, and previous use of an intrauterine device. Prior medical induced abortion was associated with a risk of ectopic pregnancy (adjusted odds ratio = 2.8, 95% CI: 1.1, 7.2); no such association was observed for surgical abortion (adjusted odds ratio = 1.1, 95% CI: 0.8, 1.6). The total attributable risk of all the factors investigated was 0.76. As close associations were found between ectopic pregnancy and infertility and between ectopic pregnancy and spontaneous abortion, further research into ectopic pregnancy should focus on risk factors common to these conditions. In terms of public health, increasing awareness of the effects of smoking may be useful for ectopic pregnancy prevention. [ABSTRACT FROM PUBLISHER]
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- 2003
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14. Acceptability and confidence in antiretroviral generics of physicians and HIV-infected patients in France.
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Allavena, Clotilde, Jacomet, Christine, Pereira, Bruno, Morand-Joubert, Laurence, Bagheri, Haleh, Cotte, Laurent, Garaffo, Rodolphe, Gerbaud, Laurent, and Dellamonica, Pierre
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HIV infections ,THERAPEUTICS ,ANTIRETROVIRAL agents ,SOCIODEMOGRAPHIC factors ,SYMPTOMS ,PUBLIC health - Abstract
Introduction Switching brand name medications to generics is recommended in France in the interest of cost effectiveness but patients and physicians are sometimes not convinced that switching is appropriate. Some antiretroviral (ARV) generics (ZDV, 3TC, NVP) have been marketed in France since 2013. Materials and Methods A multicentric cross-sectional survey was performed in September 2013 to evaluate the perception of generics overall and ARV generics in physicians and HIV-infected patients and factors associated to their acceptability. Adult HIV outpatients were asked to complete a self-questionnaire on their perception of generics. Physicians completed a questionnaire on the acceptability of generics and ARV generics. Socio-demographic data, medical history and HIV history were collected. Results 116 physicians in 33 clinics (68% in University Hospital) included 556 patients (France-native 77%, active employment 59%, covered by social Insurance 100%, homosexual/bisexual contamination 47%, median HIV duration 13 years, hepatitis coinfection 16%, on ARV therapy 95%). Overall, patients accepted and had confidence in generics in 76% and 55% of the cases, respectively. Switching ARVs for generics was accepted by 44% of the patients but only by 17% if the pill burden was going to increase. 75% of the physicians would prescribe generics, but this decreased to only 26% if the combo had to be broken. The main reasons for non-prescription of generics were previous brand name ARV-induced side effects (35%), refusal of generics overall (37%), lack of understanding of generics (26%), risk of non-observance of treatment (44%), anxiety (47%) and depressive symptoms (25%). In multivariate analysis, factors associated with the acceptability of ARV generics in patients were the use of generics overall (p<0.001) and in physicians, the absence of concern regarding the drug efficacy (p<0.001) and being aware that the patient would accept generics overall (p=0.03) and ARV generics (p=0.04). No factors related to sociodemographic conditions, HIV status or comorbidities had a constrictive influence on the use of ARV generics. Conclusion Acceptability of ARV generics in this French population is mostly dictated by the patient's and physician's knowledge and use of generics overall. Switching ARV brand name to a generic would be better accepted if the pill burden remained unchanged. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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15. Tackling the alcohol issue in France.
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Blanquet, Marie, Peyrol, M. M. E. Fleur, Gerbaud, Laurent, Morel, Florence, Maradeix, Bernard, Llorca, Pierre-Michel, and Morge, André
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ALCOHOLISM ,WOUNDS & injuries - Abstract
A letter to the editor is presented in response to the article "Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders" in the previous issue.
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- 2014
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16. Limited effect of a self-management exercise program added to spa therapy for increasing physical activity in patients with knee osteoarthritis: A quasi-randomized controlled trial.
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Gay, Chloé, Guiguet-Auclair, Candy, Coste, Nicolas, Boisseau, Nathalie, Gerbaud, Laurent, Pereira, Bruno, and Coudeyre, Emmanuel
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PHYSICAL activity , *BALNEOLOGY , *OSTEOARTHRITIS , *CLUSTER randomized controlled trials , *PHYSICAL therapy , *EXERCISE , *HEALTH resorts , *KNEE - Abstract
• We confirm the efficacy of spa therapy in knee osteoarthritis (KOA) for pain and disability. • We show for the first time that spa therapy may help increase physical activity in patients with KOA, with limited effect of an additional self-management exercise program. • The benefits of a self-management education program were a significant alleviation of fears and beliefs about KOA and physicians (KOFBeQ) and anxiety (HAD) at 3 months after treatment. The efficacy of spa therapy in osteoarthritis (OA) has ever been demonstrated, with a good level of evidence for pain and disability. The effect of a self-management program with spa therapy on physical activity (PA) level has never been demonstrated. This study aimed to assess, at 3 months, the effectiveness of 5 sessions of a self-management exercise program in patients with knee OA (KOA) who benefit from 18 days of spa therapy and received an information booklet (on proposed physical exercises) on improvement in at least one PA level. This was an interventional, multicentre, quasi-randomized controlled trial with a cluster randomized design (1-month period). People 50 to 75 years old with symptomatic knee OA were included in 3 spa therapy centres in France (Bourbon Lancy, Le Mont Dore, Royat). Both groups received conventional spa therapy sessions during 18 days and an information booklet on the benefits of PA practice for KOA. The intervention group additionally received 5 self-management exercise sessions. The main outcome was improvement in at least one PA level according to the International Physical Activity Questionnaire (IPAQ) short-form categorical score (low to moderate or high, or moderate to high) at 3 months. Secondary outcomes were the evolution of PA (MET-min/week), disability, pain, anxiety, depression, self-efficacy, fears and beliefs concerning KOA, barriers to and facilitators of regular PA practice, consumption of painkillers and adherence to physical exercise program at 3 months. Assessors but not participants or caregivers were blinded. In total, 123 patients were randomized, 54 to the intervention group and 69 to the control group. Considering the main outcome, at 3 months, 37% of patients in the intervention group showed improvement in at least one PA level according to the IPAQ categorical score versus 30.4% in the control group (P = 0.44). In the intervention group, 13 (24.1%) patients showed improvement from low to moderate PA level (vs. 8 [11.6%] in the control group), 2 (3.7%) from low to high (vs. 2 [2.9%]) and 5 (9.3%) from moderate to highvs. 11 [15.9%]). Both intervention and control groups showed increased IPAQ continuous scores (MET-min/week) at 3 months, although not significantly. HAD anxiety and depression scores were significantly reduced in the intervention group (P = 0.001 and P = 0.049, respectively) and the perception of PA was better in the intervention than control group for motivation and barriers scores (P = 0.019 and P = 0.002, respectively). This study showed the lack of impact of a short self-management program on PA level in addition to 18-day spa therapy for KOA, but both intervention and control groups showed improved PA level. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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17. Deprescribing in older adults in a French community: a questionnaire study on patients' beliefs and attitudes.
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Geremie T, Guiguet-Auclair C, Laroche ML, Mely P, Gerbaud L, and Blanquet M
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- Humans, Female, Male, Aged, France, Surveys and Questionnaires, Aged, 80 and over, Polypharmacy, Health Knowledge, Attitudes, Practice, Patient Satisfaction, Deprescriptions
- Abstract
Background: General practitioners (GPs) have a central role to play on reduction of polypharmacy and deprescribing. This study aimed to assess beliefs and attitudes towards deprescribing in patients, aged 65 years or older in primary care, and to identify factors associated with deprescribing and their willingness to stop medication., Methods: A questionnaire study was performed between 23 May and 29 July 2022 on patients aged 65 years or older attending a GP's surgery in a French area. We used the French version of the revised Patients' Attitudes Towards Deprescribing self-report questionnaire (rPATD), which measures four subscales ("Burden", "Appropriateness", "Concerns about stopping" and, "Involvement"), patients' willingness to stop one of their regular medicines, and patients' satisfaction with their current medicines., Results: The study enrolled 200 patients. Median age was 76 years old (IQR 71-81), 55% were women, and 42.5% took 5 or more medications per day. Although most patients (92.5%) were satisfied with their current medicines, 35% were reluctant to stop medications they had been taking for a long time, and 89.5% were willing to stop medication if asked to by their GP. Patients aged less than 75 years old reported more concerns about stopping. Women and patients with higher educational attainment showed significantly higher involvement in medication management., Conclusions: The majority of older adults were willing to stop one or more of their regular medicines if asked to do so by their GP. GPs should address deprescribing into their current practice., (© 2024. The Author(s).)
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- 2024
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18. Selflife : A Life Skills Development Tool to Prevent Sexual Violence among Healthcare Students.
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Pires S, Denizot H, Boudoukha AH, Mennuti J, Miele C, Potard C, Riquoir G, Llorca PM, Flaudias V, and Gerbaud L
- Subjects
- Female, Humans, Male, France, Self Report, Students psychology, Surveys and Questionnaires, Sex Offenses prevention & control
- Abstract
Background: in France, 14.5% of women and 3.9% of men aged 20-69 years have experienced sexual violence. Of these, 40% will go on to develop posttraumatic stress disorder. Sexual violence is therefore a major public health issue. In the present study, we tested a life skills development tool ( Selflife ) designed to prevent sexual violence in a population of healthcare students., Methods: a total of 225 French healthcare students were randomly divided into a control group using case studies ( n = 114) and a group using Selflife ( n = 111) to discuss the topic of sexual violence. After the session, they completed self-report questionnaires collecting sociodemographic data and probing their feelings about their participation, their life skills, and their verdict on the intervention., Results: compared with controls, participants in the Selflife group reported gaining more knowledge about sexual violence, a greater sense of improving their life skills, and greater satisfaction with the intervention., Conclusions: these results suggest that, in addition to providing information about sexual violence, Selflife helped students develop their life skills, thereby empowering them to act when confronted with sexual violence. Its impact on prevalence and on the psychological and psychiatric consequences remains to be assessed., Competing Interests: The authors declare no conflict of interest.
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- 2023
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19. Modelling the determinants of health and cancers as perceived by children: using imagery as a mediator of expression and narration.
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Gay C, Deyra M, Berland P, Gerbaud L, and Pizon F
- Subjects
- Child, Female, France epidemiology, Health Behavior physiology, Health Services Accessibility statistics & numerical data, Humans, Imagery, Psychotherapy statistics & numerical data, Male, Narration, Needs Assessment, Neoplasms prevention & control, Qualitative Research, Social Work statistics & numerical data, Imagery, Psychotherapy methods, Neoplasms psychology, Perception physiology, Schools statistics & numerical data
- Abstract
Objectives: To model and analyse conceptions of determinants of health and cancer that are expressed and perceived by school children aged 6-11 based on a multiphase qualitative protocol., Methodology: This is a multicentric, qualitative study of human and social sciences conducted among school children aged 6-11 years old. Two different tools were used, e.Photoexpression and Photonarration, in four French schools. This innovative and exploratory method addresses global health during the first phase (e.Photoexpression) and the theme of cancer during the second phase (Photonarration). The children express themselves through photography and narration., Results: 1498 qualitative productions were made by 381 children aged 6-11 years old. The analysis of these productions of expression and narration through images allowed modelling of determinants of health and cancer as perceived by children through 7 fields and 28 categories. The conceptions of determinants of health and child cancer refer to rationalities that are centred on individual determinants (76%), minimise environmental determinants (20%) and conceal the parameters of access to healthcare and social services (3%)., Discussion: These findings provide new data to the international literature on children's perceptions of determinants of health and cancer. These research findings, which can be applied to interventions and current practices, will enable prevention workers to act more effectively, closer to children's perceptions and needs., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2021
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20. Nasopharyngeal swab-induced pain for SARS-CoV-2 screening: A randomised controlled trial of conventional and self-swabbing.
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Moisset X, Gautier N, Godet T, Parabère S, Pereira B, Meunier E, Gerbaud L, Lesens O, Henquell C, Beytout J, and Clavelou P
- Subjects
- Female, France, Health Personnel, Humans, Pain diagnosis, COVID-19, SARS-CoV-2
- Abstract
Background: Massive screening campaigns for SARS-CoV-2 are currently carried out throughout the world, relying on reverse-transcriptase-polymerase chain reaction (RT-PCR) following nasopharyngeal swabbing performed by a healthcare professional. Yet, due to the apprehension of pain induced by nasopharyngeal probing, poor adhesion to those screening campaigns can be observed. To enhance voluntary participation and to avoid unnecessary exposition to SARS-CoV-2, self-swabbing could be proposed. To date, no data have been published concerning pain induced by conventional- or self-swabbing. Thus, the primary objective of the present study was to evaluate pain induced with the conventional swabbing method and compare it to self-swabbing. Secondary objectives focused on swabbing-induced discomfort and acceptability of the two methods., Methods: The study was conducted in Clermont-Ferrand medical school (France). Overall, 190 students were randomised into two groups and experienced either self- or conventional-swabbing. Each subject had to rate pain, discomfort and acceptability of such swabbing on a 0-10 numeric rating scale., Results: No significant difference was found between the two methods. The mean pain level was 2.5 ± 1.9, 28% rating pain as ≥4/10. Discomfort was 4.8 ± 2.2, 66% indicating significant (≥4/10) discomfort. Higher pain and discomfort were associated with female sex. Acceptability was ≥8/10 for 89.0% of the subjects and all would have accepted to undergo a new test with the same technique if necessary., Conclusion: Both conventional and self-swabbing induce low levels of pain for most young healthy volunteers whereas discomfort is very frequent. Nonetheless, both methods are indifferently well-accepted in medical students. Future studies amongst symptomatic subjects are awaited., Significance: Using the thinnest available swabs, procedural pain induced by nasopharyngeal swabbing for SARS-CoV-2 screening is very low for most subjects and should not limit voluntary participation in screening campaigns. Self-swabbing does not lead to more pain or discomfort compared to conventional swabbing, is well-accepted, and could be proposed to optimize screening campaigns, at least in healthcare professionals., (© 2021 European Pain Federation - EFIC®.)
- Published
- 2021
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21. Analysis of the cost effectiveness of different strategies for the antenatal diagnosis of chromosomal aberrations in cases of ultrasound-identified fetal abnormalities.
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Mourgues C, Eymard-Pierre E, Laurichesse-Delmas H, Gerbaud L, Gouas L, Pébrel-Richard C, Vago P, Debost-Legrand A, and Goumy C
- Subjects
- Adult, Algorithms, Cost-Benefit Analysis, Cytogenetic Analysis economics, Cytogenetic Analysis methods, Decision Trees, Female, Fetal Diseases genetics, Fetus diagnostic imaging, France, Humans, Karyotyping economics, Karyotyping methods, Predictive Value of Tests, Pregnancy, Retrospective Studies, Chromosome Aberrations, Fetal Diseases diagnosis, Fetus abnormalities, Prenatal Diagnosis economics, Prenatal Diagnosis methods, Ultrasonography, Prenatal economics
- Abstract
Objective: Principal objective of this work was to analyse the cost effectiveness of different sequences of cytogenetic techniques from the hospital's point of view, after prenatal ultrasound has identified fetal malformations., Methods: Cytogenetic tests were performed for each case in 3 strategies, and their results are reported and compared to one reference strategy. Two new simulated strategies were considered: chromosomal microarrays alone and a direct test + CMA., Main Outcomes Measures: cost-effectiveness ratio., Results: A single test result was positive in 234 of the 835 pregnancies studied (28%). CMA alone would have identified 239 abnormalities. In the simulated direct test + CMA sequence, the direct test alone would have been positive for 66.1% of the abnormalities identified. When testing was indicated for NT, reference strategy (Direct + karyotyping) costs 1 084.8 euros by positive test results. Strategies Direct + CMA and CMA alone cost respectively 992.7 and 550.0 euros by positive test results. For OUM indications, reference strategy costs 2 937.8 euros by positive test results. Strategies Direct + CMA and CMA alone cost respectively, 2 118.4 and 1 304.7 euros by positive test results., Conclusions: CMA appears to be the most effective test for prenatal cytogenetic diagnosis of fetal abnormalities identified by ultrasound.
- Published
- 2020
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22. Hospital and Population-Based Evidence for COVID-19 Early Circulation in the East of France.
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Gerbaud L, Guiguet-Auclair C, Breysse F, Odoul J, Ouchchane L, Peterschmitt J, Dezfouli-Desfer C, and Breton V
- Subjects
- Betacoronavirus, COVID-19, Epidemiological Monitoring, France epidemiology, Humans, Mass Behavior, Pandemics, Retrospective Studies, SARS-CoV-2, Coronavirus Infections epidemiology, Coronavirus Infections transmission, Pneumonia, Viral epidemiology, Pneumonia, Viral transmission
- Abstract
Background: Understanding SARS-CoV-2 dynamics and transmission is a serious issue. Its propagation needs to be modeled and controlled. The Alsace region in the East of France has been among the first French COVID-19 clusters in 2020., Methods: We confront evidence from three independent and retrospective sources: a population-based survey through internet, an analysis of the medical records from hospital emergency care services, and a review of medical biology laboratory data. We also check the role played in virus propagation by a large religious meeting that gathered over 2000 participants from all over France mid-February in Mulhouse., Results: Our results suggest that SARS-CoV-2 was circulating several weeks before the first officially recognized case in Alsace on 26 February 2020 and the sanitary alert on 3 March 2020. The religious gathering seems to have played a role for secondary dissemination of the epidemic in France, but not in creating the local outbreak., Conclusions: Our results illustrate how the integration of data coming from multiple sources could help trigger an early alarm in the context of an emerging disease. Good information data systems, able to produce earlier alerts, could have avoided a general lockdown in France., Competing Interests: The authors declare that there is no conflict of interest.
- Published
- 2020
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23. French survey on the crossed needs on sexual health for chronic inflammatory rheumatism patients and healthcare professionals.
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Savel C, Cherillat MS, Berland P, Tronche AM, Soubrier M, Gerbaud L, Guiguet-Auclair C, and Malochet Guinamand S
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- Adult, Arthritis, Psoriatic psychology, Arthritis, Rheumatoid psychology, Cross-Sectional Studies, Female, France, Humans, Male, Middle Aged, Needs Assessment, Physician-Patient Relations, Sexual Dysfunction, Physiological psychology, Sexual Health education, Spondylarthritis psychology, Surveys and Questionnaires, Arthritis, Psoriatic complications, Arthritis, Rheumatoid complications, Attitude of Health Personnel, Sexual Dysfunction, Physiological complications, Spondylarthritis complications
- Abstract
Patients with Inflammatory Chronic Rheumatic disease have approximately three times more sexual dysfunction than the healthy population. However, health professionals do not dare to discuss the subject with them, largely because they do not feel educated on the subject. To define the educational needs in the sexual health of health professionals involved in patient education and those of patients with Inflammatory Chronic Rheumatic disease. This French multicenter cross-sectional online study included health professionals involved in patient education and patients with Inflammatory Chronic Rheumatic disease. Two surveys were designed to assess, both of them the specific needs. They were filled out anonymously online with a secured server. The influence of professionals and patients' characteristics on their sexual health needs were tested. 57 health professionals and 239 patients answered. 71,6% of the patients reported sexual difficulties and 79,9% had never discussed them with health professionals. To facilitate discussion, the health professionals most often wanted a colleague specialized in sexual health in their team (59,7%) and access to tools (52,6%). The patients' primary expectations were psychological support (65.7%), information (51.9%), and referral to specialists if needed (43.1%). The topics the health professionals and patients considered most useful were adverse effects of treatment and impact of rheumatism on sexuality and body image. 70,2% of the health professionals felt they needed training. This survey demonstrates the need to offer educational training to health professionals designed to enable them to address and discuss sexual health issues and give their patients appropriate advice.
- Published
- 2020
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24. Level of obesity is directly associated with the clinical and functional consequences of knee osteoarthritis.
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Raud B, Gay C, Guiguet-Auclair C, Bonnin A, Gerbaud L, Pereira B, Duclos M, Boirie Y, and Coudeyre E
- Subjects
- Aged, Body Mass Index, Cross-Sectional Studies, Disease Progression, Exercise, Female, France epidemiology, Humans, Male, Middle Aged, Obesity complications, Osteoarthritis, Knee complications, Quality of Life, Risk Factors, Surveys and Questionnaires, Obesity epidemiology, Osteoarthritis, Knee epidemiology
- Abstract
Obesity is one of the most important risk factors of knee osteoarthritis (KOA), but its impact on clinical and functional consequences is less clear. The main objective of this cross-sectional study was to describe the relation between body mass index (BMI) and clinical expression of KOA. Participants with BMI ≥ 25 kg/m
2 and KOA completed anonymous self-administered questionnaires. They were classified according to BMI in three groups: overweight (BMI 25-30 kg/m2 ), stage I obesity (BMI 30-35 kg/m2 ) and stage II/III obesity (BMI ≥ 35 kg/m2 ). The groups were compared in terms of pain, physical disability, level of physical activity (PA) and fears and beliefs concerning KOA. Among the 391 individuals included, 57.0% were overweight, 28.4% had stage I obesity and 14.6% had stage II/III obesity. Mean pain score on a 10-point visual analog scale was 4.3 (SD 2.4), 5.0 (SD 2.6) and 5.2 (SD 2.3) with overweight, stage I and stage II/III obesity, respectively (p = 0.0367). The mean WOMAC function score (out of 100) was 36.2 (SD 20.1), 39.5 (SD 21.4) and 45.6 (SD 18.4), respectively (p = 0.0409). The Knee Osteoarthritis Fears and Beliefs Questionnaire total score (KOFBEQ), daily activity score and physician score significantly differed among BMI groups (p = 0.0204, p = 0.0389 and p = 0.0413, respectively), and the PA level significantly differed (p = 0.0219). We found a dose-response relation between BMI and the clinical consequences of KOA. Strategies to treat KOA should differ by obesity severity. High PA level was associated with low BMI and contributes to preventing the clinical consequences of KOA.- Published
- 2020
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25. Economic analysis of a nurse-led programme for comorbidities management of rheumatoid arthritis patients.
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Mourgues C, Blanquet M, Gerbaud L, Soubrier M, and Dougados M
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- Arthritis, Rheumatoid nursing, Disease Management, Female, France, Humans, Male, Middle Aged, Nurse's Role, Practice Patterns, Nurses' economics, Program Evaluation, Severity of Illness Index, Arthritis, Rheumatoid economics, Arthritis, Rheumatoid therapy, Comorbidity, Cost-Benefit Analysis, Practice Patterns, Nurses' organization & administration
- Abstract
Objectives: Rheumatoid arthritis (RA) cause major functional, psychological, social and occupational repercussions for patients and has important economic consequences for society. The principal objective of this work was to determine the economic pertinence of a staff nurse specialised in preventive management for these patients., Methods: The COMEDRA multicentre randomised controlled clinical trial, conducted from March 2011 to June 2012, showed the effectiveness of a nurse-led programme dedicated to the management of comorbidities trough the promotion of 11 preventive procedures. A cost-benefit analysis, from a societal perspective and based on direct medical cost, was conducted to assess the equivalence of the cost of the nurse-led programme and the cost of the additional preventive procedures performed, engendered by the programme. The programme was considered effective if its cost was less than or equal to the costs of the additional preventive procedures. The costs were calculated from the approved health insurance charges. From the total costs induced, a contributive share was measured, corresponding to the ratio of the total costs of each type of procedure to the overall total cost., Results: The cost of the intervention was assessed at €16,804.2. This intervention contributed to the performance of 747 additional preventive procedures, at a cost of €30,184.8. This intervention with these patients is financially balanced when at least 37 patients follow the recommendations for every preventive procedure., Conclusions: From the hospital's perspective and from both a medical and economic point of view, a nurse-led programme to manage the comorbidities of RA is useful., (Copyright © 2017 Société française de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.)
- Published
- 2018
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26. Positive and cost-effectiveness effect of spa therapy on the resumption of occupational and non-occupational activities in women in breast cancer remission: a French multicentre randomised controlled trial.
- Author
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Mourgues C, Gerbaud L, Leger S, Auclair C, Peyrol F, Blanquet M, Kwiatkowski F, Leger-Enreille A, and Bignon YJ
- Subjects
- Adult, Aged, Cost-Benefit Analysis, Diet Therapy economics, Diet Therapy methods, Diet Therapy psychology, Female, France, Humans, Massage, Middle Aged, Occupational Therapy methods, Relaxation Therapy methods, Remission Induction, Steam Bath, Survivors psychology, Activities of Daily Living psychology, Breast Neoplasms rehabilitation, Occupational Therapy economics, Occupational Therapy psychology, Relaxation Therapy economics, Relaxation Therapy psychology
- Abstract
Purpose of the Research: The main aim was to assess the effects of a spa treatment on the resumption of occupational and non-occupational activities and the abilities of women in breast cancer remission. A cost-effectiveness analysis (CEA) was also performed., Methods and Sample: A multicentre randomised controlled trial was carried out between 2008 and 2010 in the University Hospital of Auvergne and two private hospitals in Clermont-Ferrand, France. Eligible patients were women in complete breast cancer remission without contraindication for physical activities or cognitive disorders and a body mass index between 18.5 and 40 kg/m(2). The intervention group underwent spa treatment combined with consultation with dietician whereas the control underwent consultations with the dietician only. Of the 181 patients randomised, 92 and 89 were included in the intervention and the control groups, respectively. The CEA involved 90 patients, 42 from the intervention group and 48 from the control group., Key Results: The main results showed a higher rate of resumption of occupational activities in the intervention group (p = 0.0025) and a positive effect of the intervention on the women's ability to perform occupational activities 12 months after the beginning of the study (p = 0.0014), and on their ability to perform family activities (p = 0.033). The stay in a thermal centre was cost-effective at 12 months., Conclusions: Spa treatment is a cost-effective strategy to improve resumption of occupational and non-occupational activities and the abilities of women in breast cancer remission., (Copyright © 2014 Elsevier Ltd. All rights reserved.)
- Published
- 2014
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27. Appropriateness of elective caesarean deliveries in a perinatal network: a cross-sectional study.
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Vendittelli F, Tassié MC, Gerbaud L, and Lémery D
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- Adult, Cesarean Section statistics & numerical data, Cross-Sectional Studies, Female, Follow-Up Studies, France, Humans, Infant, Newborn, Pregnancy, Retrospective Studies, Risk Factors, Cesarean Section methods, Elective Surgical Procedures, Perinatal Care methods
- Abstract
Background: The overall caesarean rate in France has increased from 14.3% in 1994-1996 to 21.0% in 2010. This increased rate is a concern in all developed countries: delivery by caesarean induces both short- and long-term maternal complications, and its use requires careful reflection. The principal objective of this work was to describe the global appropriateness of indications for caesareans among a selected sample of planned caesareans performed within the Auvergne perinatal health network. The secondary objectives were to describe the inappropriate planned caesarean risk according to the maternity unit level and the impact of this medical assessment on the global caesarean rate in this network., Methods: This audit among maternity units belonging to the Auvergne perinatal network in France included women who had a planned caesarean at term, were nulliparous or primiparous, and had a singleton pregnancy in cephalic presentation or a twin pregnancy with twin 1 in cephalic presentation. We used the French guidelines issued from 1998 through 2010 as our benchmark for appropriateness., Result: We analysed 192 cases (100% of the records eligible for the audit). The rate of appropriate caesareans among these planned caesareans was 65.6%. Among the inappropriate caesareans, the rate of "maternal-preference" caesareans was 12.0% and the rate of "provider-preference" caesareans 22.4%. The risk of an inappropriate caesarean did not differ statistically between the level I and level II maternity wards, each compared to the level III hospital. The overall caesarean rate in our entire network decreased from 20.5% to 18.5% (p < 0.001) in the year after the audit. It also decreased in 8 of the network's 10 maternity units, although the difference was statistically significant only in 2., Conclusions: About one third of planned caesareans were inappropriate in our sample and our audit appeared to have some effect on medical practice in the short run.
- Published
- 2014
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28. A caregiver educational program improves quality of life and burden for cancer patients and their caregivers: a randomised clinical trial.
- Author
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Belgacem B, Auclair C, Fedor MC, Brugnon D, Blanquet M, Tournilhac O, and Gerbaud L
- Subjects
- Adaptation, Psychological, Adult, Aged, Caregivers psychology, Curriculum, Female, France, Humans, Male, Middle Aged, Neoplasms diagnosis, Neoplasms economics, Program Evaluation, Reference Values, Social Support, Statistics, Nonparametric, Caregivers education, Cost of Illness, Health Education methods, Neoplasms therapy, Quality of Life
- Abstract
Purpose of the Research: The French setting, including laws and guidelines, advocates greater involvement of informal caregivers in the care of cancer patients to protect the caregivers from depression, distress, and a decrease in their quality of life. This study aimed to assess the efficacy of a caregiver educational programme by measuring two outcomes: patients' and caregivers' quality of life and caregivers' burden., Methods and Sample: A multicentre randomised controlled trial was performed in six oncology wards in French hospitals. Eligible patients had a cancer, a main caregiver, allowed their caregivers' involvement, and received an inclusion agreement by a doctor/psychologist dyad. The experimental group participated in an educational programme performed by nurses to improve their skills in meal support, nursing care, welfare care, or symptom management. The SF36 and the Zarit burden scales were used to measure quality of life and caregivers' burden at the beginning and at the end of the study., Key Results: 67 patients were randomised and 33 were included in the experimental group. Evolution scores, which measured the difference between baseline and final scores, showed an improvement in patients' and caregivers' quality of life and an alleviated burden for experimental group caregivers., Conclusions: An educational programme for caregivers encourages the involvement of patients, informal caregivers and health-care providers in a triangular relationship which enhances the quality of life of patients and caregivers alike and decreases caregivers' burden. Care organisation should therefore be rethought as a triangular relationship between patients, caregivers and health-care providers, with nurses as the mainstay., (Copyright © 2013 Elsevier Ltd. All rights reserved.)
- Published
- 2013
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29. Relationship between inpatient satisfaction and nurse absenteeism: an exploratory study using WHO-PATH performance indicators in France.
- Author
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Moret L, Anthoine E, Paillé C, Tricaud-Vialle S, Gerbaud L, Giraud-Roufast A, Michel P, and Lombrail P
- Subjects
- Aged, Female, France, Hospitals, Humans, Inpatients psychology, Male, Middle Aged, Nurses organization & administration, Quality Assurance, Health Care, Sick Leave statistics & numerical data, Surveys and Questionnaires, Absenteeism, Employee Performance Appraisal, Inpatients statistics & numerical data, Patient Satisfaction statistics & numerical data, Quality of Health Care
- Abstract
Background: Indicators describing results of care are widely explored in term of patient satisfaction (PS). Among factors explaining PS, human resources indicators have been studied in terms of burnout or job satisfaction among healthcare professionals. No research work has set out to explore the effect of absenteeism on PS scores. The objective of this study was to explore interaction between rate of absenteeism among nurses and PS results., Methods: France has taken part in a project named PATH (Performance Assessment Tool for Hospitals) of the World Health Organization, aiming to develop a tool for the assessment of hospital performance. In the first semester 2008, 25 volunteering short-stay hospitals (teaching, general and private) provide complete data on nurse short-absenteeism (periods of up to 7 consecutive days of sick leave) and on PS (a cross-sectional postal survey using a standardized validated French-language scale EQS-H exploring "quality of medical information" (MI) and "relationships with staff and daily routine" (RS)). A multi-level model was used to take into account of the hierarchical nature of the data., Results: Two thousand and sixty-five patients responded to the satisfaction questionnaire (participation rate: 40.9%). The mean age of respondents was 58 yrs (± 19), 41% were men. The mean duration of hospitalisation was 7.5 days (± 11.1). The mean absenteeism rate for nurses was 0.24% (± 0.14).All the PS scores were significantly and negatively correlated with rate of short-absenteeism among nurses (MI score: ρ = -0.55, p < 0.01), RS score ρ = -0.47, p = 0.02). The mixed model found a significant relationship between rate of absenteeism among nurses and PS scores (MI: p = 0.027; RS: p = 0.017)., Conclusion: Results obtained in this study show that short-term absenteeism among nurses seems to be significantly and negatively correlated with PS. Our findings are an invitation to deepen our understanding of the impact of human resources on PS and to develop more specific projects.
- Published
- 2012
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30. Validation of a French hospitalized patients' satisfaction questionnaire: the QSH-45.
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Antoniotti S, Baumstarck-Barrau K, Siméoni MC, Sapin C, Labarère J, Gerbaud L, Boyer L, Colin C, François P, and Auquier P
- Subjects
- Adult, Aged, Female, France, Hospital Departments, Humans, Male, Middle Aged, Psychometrics, Quality Assurance, Health Care, Reproducibility of Results, Socioeconomic Factors, Hospitalization, Patient Satisfaction, Surveys and Questionnaires
- Abstract
Objective: To develop a generic French self-administered instrument for measuring hospitalized patients' satisfaction based on the patient's point of view: the questionnaire for satisfaction of hospitalized (QSH) patients., Design: The development was supervised by a steering committee and undertaken through three standard steps. Item generation was derived from 95 face-to-face interviews, performed in hospitalized patients and in patients scheduled to be admitted. The item reduction led to a 69-item questionnaire. The validation process was based on validity, reliability and some aspects of external validity., Setting: Medical, surgical and obstetrical departments (n = 187) of public hospitals (n = 11) from different French regions (n = 3)., Participants: Eligible patients were adult subjects hospitalized for at least 24 h., Main Outcome Measures: QSH, sociodemographic data, hospitalization department, visual analogue scales of satisfaction., Results: The final version of QSH contained 45 items describing 9 dimensions, leading to 2 composite scores (staff and structure index). The factor structure accounted for 71% of the total variance. Internal consistency was satisfactory (item-internal consistency over 0.40; Cronbach's alpha coefficients ranged from 0.76 to 0.96). The scalability was satisfactory with inlier-sensitive fit (INFIT) statistics inside an acceptable range. Scores of dimensions were strongly positively correlated with visual analogue scale scores (all P < 0.001). External validity showed statistical associations between QSH scores and age or department. Participation rate was 91%., Conclusions: The availability of a reliable and valid French questionnaire concerning hospitalized patients' satisfaction, exclusively generated from patients' interviews, enables patient feedback to be incorporated in a continuous quality health-care improvement strategy.
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- 2009
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31. Prevalence of iron deficiency and health-related quality of life among female students.
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Grondin MA, Ruivard M, Perrève A, Derumeaux-Burel H, Perthus I, Roblin J, Thiollières F, and Gerbaud L
- Subjects
- Adolescent, Adult, Cross-Sectional Studies, Female, France epidemiology, Humans, Quality of Life, Statistics, Nonparametric, Surveys and Questionnaires, Ferritins blood, Iron Metabolism Disorders blood, Iron Metabolism Disorders epidemiology, Students
- Abstract
Objective: To investigate prevalence of iron deficiency and examine the relationship between iron status and Health-related Quality of Life among female students., Design: Cross-sectional study., Subjects and Setting: Data were collected from 543 female students, aged 17 to 38 years, attending University or secondary schools in Clermont-Ferrand (France) and its metropolitan area. Three groups were defined, according to the rate of serum ferritin: iron deficient (serum ferritin < 15 microg/L), iron depletion borderline (serum ferritin 15-20 microg/L), and iron replete (serum ferritin > 20 microg/L). Those 3 groups of menstruating female students were compared in terms of health-related quality of life using univariate analysis., Measures of Outcome: Health-related Quality of Life based on SF-36 questionnaire, and iron status measured by serum ferritin., Results: The prevalence of iron deficiency was 19.3%, the prevalence of borderline iron status was 11.4%. Regarding the SF-36 questionnaire, the only significant difference between iron deficient and iron replete female students concerned the dimension reflecting 'general health', which was significantly lower in iron deficient group (p = 0.015)., Conclusion: Iron deficiency seems to impair the perceived general health in female students. Further research should be conducted on this little known subject.
- Published
- 2008
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32. Psychopathological features of a patient population of targets of workplace bullying.
- Author
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Brousse G, Fontana L, Ouchchane L, Boisson C, Gerbaud L, Bourguet D, Perrier A, Schmitt A, Llorca PM, and Chamoux A
- Subjects
- Adult, Anxiety Disorders psychology, Depressive Disorder psychology, Female, France, Humans, Male, Middle Aged, Occupational Diseases psychology, Pilot Projects, Prospective Studies, Stress, Psychological psychology, Workplace psychology, Anxiety Disorders diagnosis, Depressive Disorder diagnosis, Occupational Diseases diagnosis, Social Behavior, Stress, Psychological diagnosis
- Abstract
Background: A strong association between workplace bullying and subsequent anxiety and depression, indicated by empirical research, suggests that bullying is an aetiological factor for mental health problems., Aims: To evaluate levels of stress and anxiety-depression disorder developed by targets of workplace bullying together with outcome at 12 months and to characterize this population in terms of psychopathology and sociodemographic features., Methods: Forty-eight patients (36 women and 12 men) meeting Leymann Inventory of Psychological Terror criteria for bullying were included in a prospective study. Evaluations were performed at first consultation and at 12 months using a standard clinical interview, a visual analogue scale of stress, the Hospital Anxiety and Depression (HAD) scale, the Beech scale of stress in the workplace and a projective test (Picture-Frustration Study)., Results: At first consultation, 81% of patients showed high levels of perceived stress at work and 83 and 52% presented with anxiety or depression, respectively. At 12 months, only 19% of working patients expressed a feeling of stress at work. There was a significant change in symptoms of anxiety while there was no change in symptoms of depression. Stress at work and depression influenced significatively capacity to go back to work. At 12-month assessments, workers showed a significantly better score on the HAD scale than non-workers. Over half the targets presented a neuroticism-related predominant personality trait., Conclusion: Workplace bullying can have severe mental health repercussions, triggering serious and persistent underlying disorders.
- Published
- 2008
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33. [Medical guidelines and medical practices: The example of lipid lowering therapy].
- Author
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Grondin MA, Ouchchane L, Ferrières J, and Gerbaud L
- Subjects
- Attitude of Health Personnel, Cholesterol, LDL blood, France, Humans, Guideline Adherence, Hyperlipidemias prevention & control, Practice Guidelines as Topic, Practice Patterns, Physicians'
- Abstract
Introduction: The SPOT epidemiologic survey assessed the results of long-term cholesterol-lowering therapy in France and the reasons why patients do or do not meet their therapeutic objectives., Objective: To assess the guidelines on which doctors base their practices for cholesterol-lowering therapy and make suggestions to improve the match between recommendations and practices., Methods: LDL cholesterol was measured in 2479 French outpatients in 2003 and classified according to whether it met therapeutic objectives of 3 different scales: the official French (AFSSAPS) recommendations issued in 2000, the physician's opinion of the ideal level for the patient, and the physician's goal level for the patient. Agreement between these 3 criteria was analyzed., Results: French doctors used guidelines stricter than the official recommendations to assess the achievement of lipid-lowering objectives., Discussion: Physicians rely more on American than French guidelines. They also considered the patient's history and clinical condition in setting individual goals.
- Published
- 2006
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34. Ectopic pregnancy is again on the increase. Recent trends in the incidence of ectopic pregnancies in France (1992-2002).
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Coste J, Bouyer J, Ughetto S, Gerbaud L, Fernandez H, Pouly JL, and Job-Spira N
- Subjects
- Adolescent, Adult, Age Distribution, Chlamydia Infections complications, Contraception adverse effects, Female, France epidemiology, Humans, Incidence, Intrauterine Devices adverse effects, Pregnancy, Pregnancy, Ectopic etiology, Pregnancy, Ectopic microbiology, Smoking adverse effects, Pregnancy, Ectopic epidemiology
- Abstract
Background: We aimed to assess the recent incidence trends of ectopic pregnancies (EP) in France (1992-2002)., Methods: A population-based register of all women aged 15-44 years with EP was set up in Auvergne (central France). We calculated rates of EP as a 'reproductive failure' or as a 'contraceptive failure', frequencies of exposure to the two main risk factors for EP (cigarette smoking and chlamydial infection) and contraceptive methods between 1992 and 2002., Results: The overall EP rate decreased by 2%, from 96.4 per 100 000 women aged 15-44 in 1992 to 95.3 per 100 000 in 2002. However, the rate of 'reproductive failure' EP increased by 17%, while the rate of 'contraceptive failure' EP, mostly intrauterine device failure, decreased by 29%., Conclusion: Appropriate analysis reveals that the rate of EP as reproductive failure is increasing again in France. This result is of interest for many European and North America countries where chlamydial infections or smoking or both are increasing in women of reproductive age. The rates of EP as contraceptive failure and of that as reproductive failure evolve differently in the population and should not be confused in epidemiological studies.
- Published
- 2004
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