1. In situ revascularization with rifampicin-soaked silver polyester graft for aortic infection: Results of a retrospective monocentric series of 18 cases.
- Author
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Vanbrugghe C, Bartoli MA, Ouaissi M, Sarlon G, Amabile P, Magnan PÉ, and Soler RJ
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Aneurysm, Infected diagnostic imaging, Aneurysm, Infected microbiology, Aneurysm, Infected mortality, Anti-Bacterial Agents adverse effects, Aortic Aneurysm diagnostic imaging, Aortic Aneurysm microbiology, Aortic Aneurysm mortality, Blood Vessel Prosthesis Implantation adverse effects, Blood Vessel Prosthesis Implantation mortality, Female, France, Hospital Mortality, Humans, Male, Middle Aged, Prosthesis Design, Prosthesis-Related Infections diagnostic imaging, Prosthesis-Related Infections microbiology, Prosthesis-Related Infections mortality, Retrospective Studies, Rifampin adverse effects, Risk Factors, Time Factors, Treatment Outcome, Young Adult, Aneurysm, Infected surgery, Anti-Bacterial Agents administration & dosage, Aortic Aneurysm surgery, Blood Vessel Prosthesis adverse effects, Blood Vessel Prosthesis Implantation instrumentation, Polyesters adverse effects, Prosthesis-Related Infections surgery, Rifampin administration & dosage, Silver adverse effects
- Abstract
Objective: To evaluate the short and long-term results of in situ prosthetic graft treatment using rifampicin-soaked silver polyester graft in patients with aortic infection., Material and Method: All the patients surgically managed in our center for an aortic infection were retrospectively analyzed. The primary endpoint was the intra-hospital mortality, secondary outcomes were limb salvage, persistent or recurrent infection, prosthetic graft patency, and long-term survival., Results: From January 2004 to December 2015, 18 consecutive patients (12 men and 6 women) were operated on for aortic infection. Six mycotic aneurysms and 12 prosthetic infections, including 8 para-entero-prosthetic fistulas, were treated. In 5 cases, surgery was performed in emergency. During the early postoperative period, we performed one major amputation and two aortic infections were persistent. Intra-hospital mortality was 27.7%. The median follow-up among the 13 surviving patients was 26 months. During follow-up, none of the 13 patients presented reinfection or bypass thrombosis., Conclusion: This series shows that in situ revascularization with rifampicin-soaked silver polyester graft for aortic infection have results in agreement with the literature in terms of intra-hospital mortality with a low reinfection rate., (Copyright © 2020 Elsevier Masson SAS. All rights reserved.)
- Published
- 2020
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