1. Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, China.
- Author
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Jiankui Liu, Chunhua Wei, Zhifeng Lin, Wei Xia, Ying Ma, Ailing Dai, and Xiaoyan Yang
- Subjects
ANIMAL herds ,NUCLEOTIDE sequencing ,RESTRICTION fragment length polymorphisms ,SEQUENCE analysis ,MOLECULAR epidemiology - Abstract
PRRS virus (PRRSV) has undergone rapid evolution and resulted in immense economic losses worldwide. In the present study, a PRRSV strain named FJ0908 causing high abortion rate (25%) and mortality (40%) was detected in a swine herd in China. To determine if a new PRRSV genotype had emerged, we characterized the genetic characteristics of FJ0908. Phylogenetic analysis indicated that FJ0908 was related to 1-7-4-like strains circulating in the United States since 2014. Furthermore, the ORF5 sequence restriction fragment length polymorphism (RFLP) pattern of FJ0908 was 1-7-4. Additionally, FJ0908 had a 100 aa deletion (aa329–428) within nsp2, as compared to VR-2332, and the deletion pattern was consistent with most of 1-7-4 PRRSVs. Collectively, the data of this study contribute to the understanding of 1-7-4-like PRRSV molecular epidemiology in China. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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