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Cotton offers next-to-skin comfort and hence is a preferred fiber for undergarments. There have been a number of studies on the effect of different fiber types, fabric structure, fabric finishes, etc. on the moisture vapor transport properties. However, there has been no report in the public domain on the relationship between cotton varieties on the moisture vapor transport characteristics of fabrics produced from them. The study reported in this paper focuses on the moisture vapor transport properties (MVTR) of cotton fabrics knitted from 31 different cotton fibers with different pedigrees grown over a three-year period in three major cotton growing regions of US, Southwest (Texas), Mid-South (Mississippi) and Southeast (Georgia). Results indicate that cotton varieties influence the MVTR of knitted fabrics produced from them. This study, for the first time has attempted to link varietal effects on the most important property of cotton--breathability quantified using MVTR. Preliminary analysis indicates a relationship between the basic sugar content such as verbascose of cotton and its moisture vapor transport. However this result has to be followed up with a thorough study. [ABSTRACT FROM AUTHOR]