1. Long-Term Facial Nerve Outcome in Primary Parotid Cancer Surgery: A Population-Based Analysis.
- Author
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Thielker J, Wahdan A, Buentzel J, Kaftan H, Boeger D, Mueller AH, Wittig A, Schultze-Mosgau S, Ernst T, and Guntinas-Lichius O
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Facial Muscles innervation, Facial Muscles surgery, Facial Nerve surgery, Facial Nerve Injuries etiology, Facial Nerve Injuries surgery, Facial Paralysis etiology, Facial Paralysis surgery, Female, Follow-Up Studies, Germany epidemiology, Humans, Male, Middle Aged, Neoplasm Staging, Parotid Gland innervation, Parotid Gland pathology, Parotid Gland surgery, Parotid Neoplasms diagnosis, Parotid Neoplasms pathology, Postoperative Complications etiology, Postoperative Complications surgery, Retrospective Studies, Risk Factors, Treatment Outcome, Young Adult, Facial Nerve Injuries epidemiology, Facial Paralysis epidemiology, Parotid Neoplasms surgery, Postoperative Complications epidemiology
- Abstract
Objectives/hypothesis: To determine immediate postoperative and long-term facial nerve dysfunction after parotid cancer surgery, risk factors, and the role of facial reanimation surgery., Study Design: Population-based long-term analysis for all new primary parotid carcinoma cases in Thuringia from 1996 to 2019., Methods: Data of the cancer registries of Thuringia, a federal state in Germany, were analyzed in combination with hospital-based data on facial function., Results: About 477 patients (42.3% women; median age: 68 years) were included. It was observed that 6.7% had a preoperative facial nerve dysfunction, 11.7% received a radical parotidectomy, that is, that 5% had a normal preoperative facial function but needed radical surgery because of intraoperative detection of tumor infiltration into the facial nerve. About 10.2% received facial nerve reconstruction surgery. Immediate postoperative facial nerve dysfunction in the other patients was observed in 34.4% of the patients. Advanced T classification (odds ratio [OR] = 2.140; confidence interval [CI] = 1.268-3.611; P = .004) and neck dissection (OR = 2.012; CI = 1.027-3.940; P = .041) were independent risk factors for immediate postoperative facial nerve dysfunction. In addition, 22.0% showed no recovery during follow-up. Advanced T classification (OR = 2.177; CI = 1.147-4.133; P = .017) and postoperative radiotherapy (OR = 2.695; CI = 1.244-5.841; P = .012) were independent risk factors for permanent postoperative facial nerve dysfunction., Conclusion: Patients with primary parotid cancer are at high risk for long-term facial nerve dysfunction. It seems that the possibilities of facial reanimation surgery needs to be utilized even more effectively., Level of Evidence: 3 Laryngoscope, 131:2694-2700, 2021., (© 2021 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc.)
- Published
- 2021
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