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The interruption of the publication of the Deutsche Zeitschrift für die gesamte gerichtliche Medizin due to the war ended with volume 39 for the years 1948/1949. Until volume 66/1969, the journal appeared unchanged under the historical title. The 912 publications contained in the 28 volumes of these two decades cover topics from the main fields of forensic medicine, but also from related and unrelated disciplines. The topic-specific analysis of the publications shows a shift of the research focus in the German institutes since the post-war period. This is most evident in the decline in the number of publications from the fields of scientific and technical criminalistics as well as forensic psychiatry and psychology. An opposite trend with a significant increase in scientific papers was observed in alcohology, forensic genetics and traffic medicine. While the evaluated publications on most topics contain new findings that are still valid today, the use of blood group characteristics for forensic purposes came to an end as a result of the introduction of DNA analysis., (© 2022. The Author(s).)

From its launc h in 1922 to the end of the Second World War, the Deutsche Zeitschrift für die gesamte gerichtliche Medizin spanned 38 volumes. The 1762 papers contained in those volumes reflect contemporary interests and include many papers from peripheral fields and non-medico-legal disciplines. Publications concerned with issues outside core legal medicine fields in particular allow two distinct tendencies in the development of German institutes of legal medicine to be discerned. Firstly, there is a focus on the psychological and psychiatric aspects of the discipline. Secondly, there is tendency towards a scientific-criminalistic outlook. The fatal consequences of the Nazi seizure of power in 1933 did not spare the sciences. For legal medicine, a discipline with close links to the state, it is unsurprising that fundamental changes to the political system had a significant impact on subject matter. Leaving aside articles notable principally for their ideological content, our analysis of the 38 volumes shows that the papers examined contain new insights into many subjects, some of which are still valid today., (© 2022. The Author(s).)

Background: It has been hypothesised that inflammatory reactions could play an important role in the pathway(s) leading to sudden and unexpected death in infancy. On a molecular level, these reactions are regulated by various cytokines., Methods: To characterise the role of IL-1ß, IL-6 and TNFα more precisely, the concentrations of these cytokines were determined quantitatively using specific ELISA techniques in serum and cerebrospinal fluid (CSF) in 119 cases of sudden infant death. The infants were grouped into four categories (SIDS, SIDS with infection, natural death due to infection and unnatural death)., Results: A good correlation was found between CSF and serum for IL-6 (Spearman correlation coefficients (SCC), 0.73) and also for TNFα (SCC, 0.57), although the CSF concentrations were lower than that from the serum. There were no significant differences between the categories of death for any of the serum or CSF cytokines. Compared with normal values, increased serum concentrations of IL-1ß, IL-6 and TNFα were found in 70%, 69% and 38% of the cases respectively, indicating possible agonal or post-mortem changes of cytokine concentrations. In three cases very high cytokine concentrations were found (mainly for IL-6). This may have contributed to the mechanism of death (cytokine storm) in two of the cases., Conclusions: In a small group of patients, very high cytokine concentrations are a possible explanation for the cause of death ("cytokine storm").

Despite its decreasing incidence, sudden infant death syndrome (SIDS) still remains an important cause of death in infancy. Since Felix Platter described the case of a child suffocated because of a massive goiter (Platter E. Suffocatio a struma interna abscondita, circa iugulum. Observationum in hominis affectibus plerisque corpori et animo, functionum lesione, dolore, aliave molestia et vitio incommodantibus. Libris tres, Part IX. Basel: König and Brandmylieri; 1614), many authors have attempted to verify the existence of a correlation between the dimensions of organs of infants and SIDS. The lack of recent published norms and the difficulty in finding a suitable control group by which to compare the cases of SIDS shows the importance of this study.This article presents the organ weights of 209 male and 132 female babies whose cause of death was SIDS. The data have been collected from 2 different studies: the Westphalian Cot Death Study from 1990 to 1994 and the German National Study on SIDS from 1998 to 2001. The organ weights increased from month to month during the first year of life showing a tendency towards higher weights in males compared with females (these are, however, not statistically significant). No significant differences compared with the recently published data of Thompson and Cohle, J Forensic Sci. 2004;49:575-585 were found.The heart weights were compared with a control group of 47 babies (21 females, 26 males) died because of both natural and unnatural causes. The weight of the organs that presented macro-microscopical pathologic changes was excluded.The weights of the heart were also compared with those published by Schulz and Giordano, Arch Pathol. 1962;74:464-471 and Kelmanson, Eur J Pediatr. 1996;155:440-444. This comparison showed minor differences which are discussed in the article. We suggest that organ weights obtained in SIDS cases can be used as norms in the first year of life.