1. Diabetes mellitus is a multivariate independent prognostic factor in endometrial carcinoma: a clinicopathologic study on 313 patients.
- Author
-
Steiner E, Plata K, Interthal C, Schmidt M, Faldum A, Hengstler JG, Sakuragi N, Watari H, Yamamoto R, and Kölbl H
- Subjects
- Adult, Aged, Comorbidity, Female, Germany epidemiology, Humans, Middle Aged, Multivariate Analysis, Neoplasm Invasiveness, Neoplasm Staging, Prognosis, Proportional Hazards Models, Retrospective Studies, Survival Analysis, Diabetes Mellitus epidemiology, Endometrial Neoplasms epidemiology, Endometrial Neoplasms pathology, Women's Health
- Abstract
Objective: The aim of this study was to analyse the influence of diabetes mellitus as a prognostic factor for overall survival in endometrial cancer., Materials and Methods: Charts were reviewed from patients with endometrial carcinoma from 1985 to 2003. Data on clinicopathologic variables, adjuvant treatment, site of recurrence and survival were collected. The chi-square test was used to examine associations between variables. The Kaplan-Meier method was used for survival analysis and Cox's proportional hazards model for multiple regression analysis., Results: Multivariate analysis revealed that diabetes mellitus, FIGO stage and depth of myometrial invasion were significantly associated with overall survival.
- Published
- 2007