8 results on '"Johnson, Elizabeth"'
Search Results
2. CYP8A1 Gene Polymorphisms and Left Main Coronary Artery Disease.
- Author
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Bousoula, Eleni, Kolovou, Vana, Vasiliadis, Ioannis, Karakosta, Agathi, Xanthos, Theodoros, Johnson, Elizabeth O., Skandalakis, Panagiotis, and Kolovou, Genovefa D.
- Subjects
CORONARY heart disease risk factors ,DNA analysis ,CHI-squared test ,CORONARY disease ,STATISTICAL correlation ,GENES ,GENETIC polymorphisms ,LIPIDS ,POLYMERASE chain reaction ,PROSTAGLANDINS ,STATISTICS ,U-statistics ,DATA analysis software ,GENETICS - Abstract
Background: Left main (LM) disease is rare but the most hazardous phenotype of coronary artery disease (CAD). Thus, early detection of participants at high risk of developing left main coronary heart disease (LM-CAD) is crucial. The aim of this study was to identify gene polymorphisms which could distinguish participants who are at high risk of developing LM-CAD. Such a candidate can be the prostaglandin I2 or prostacyclin (PGI2) gene. Methods: The DNA of 254 participants (151 participants with angiographically documented LM-CAD and 103 healthy controls) was analyzed for the frequency of C1117A polymorphism in the gene coding CYP8A1. Results: The genotype distribution was different between the LM-CAD and the control group. Particularly, the CC genotype of CYP8A1 was commoner in the LM-CAD than in the healthy group (P < .001). Allele frequencies were also differently distributed between the 2 groups. C allele frequency was higher in LM-CAD group (P = .016). Conclusions: The CC genotype of C1117A polymorphism is associated with higher risk of LM-CAD, which prospectively may have potential importance in screening high-risk populations. However, further investigations in larger populations are required to confirm these findings. [ABSTRACT FROM AUTHOR]
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- 2012
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3. Factors influencing nurses' decisions to activate medical emergency teams.
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Pantazopoulos, Ioannis, Tsoni, Aikaterini, Kouskouni, Evangelia, Papadimitriou, Lila, Johnson, Elizabeth O, and Xanthos, Theodoros
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CHI-squared test ,COMA ,STATISTICAL correlation ,CARDIOPULMONARY resuscitation ,CRITICAL care medicine ,EMPLOYEES ,EMPLOYMENT ,EXPERIENCE ,FISHER exact test ,HOSPITAL wards ,RESEARCH methodology ,MEDICAL emergencies ,NURSING practice ,NURSING assessment ,NURSING specialties ,QUESTIONNAIRES ,RESEARCH evaluation ,STATISTICAL sampling ,SCALE analysis (Psychology) ,SCALES (Weighing instruments) ,SURVEYS ,U-statistics ,DECISION making in clinical medicine ,QUANTITATIVE research ,EDUCATIONAL attainment ,SEVERITY of illness index ,RESEARCH methodology evaluation ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Aims and objectives. To evaluate the relationship between nurse demographics and correct identification of clinical situations warranting specific nursing actions, including activation of the medical emergency team. Background. If abnormal physiology is left untreated, the patient may develop cardiac arrest. Nurses in general wards are those who perceive any clinical deterioration in patients. Design. A descriptive, quantitative design was selected. Methods. An anonymous survey with 13 multiple choice questions was distributed to 150 randomly selected nurses working in general medical and surgical wards of a large tertiary hospital in Athens, Greece. After explanation of the purposes of the study, 94 nurses (response ratio: 62%) agreed to respond to the questionnaire. Results. Categories with the greatest nursing concern were patients with heart rate < 40/minute, an atypical thoracic pain, foreign body airway obstruction and bronchial secretions, respiratory rate < 5/minute and heart rate = 100/minute. However, almost 50% of nurses were able to accurately identify the critical nursing action for patients with respiratory rate < 4/minute, 72% for patients with airway obstruction and 73% for patients with chest pain. Nurses who had graduated from a four-year educational programme identified clinical situations that necessitated medical emergency team activation in a significantly higher rate and also scored significantly higher in questions concerning clinical evaluation than nurses who had graduated from a two-year educational programme. Conclusion. Activation of the medical emergency team is influenced by factors such as level of education and cardiopulmonary resuscitation courses attendance. Relevance to clinical practice. Graduating from a four-year educational programme helps nurses identify emergencies. However, irrespective of the educational programme they have followed, undertaking a basic life support or advanced life support provider course is critical as it helps them identify cardiac or respiratory emergencies. [ABSTRACT FROM AUTHOR]
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- 2012
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4. Anatomical variation and morphology in the position of the palatine foramina in adult human skulls from Greece.
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Piagkou, Maria, Xanthos, Theodore, Anagnostopoulou, Sophia, Demesticha, Theano, Kotsiomitis, Evangelos, Piagkos, Giannoulis, Protogerou, Vassilis, Lappas, Dimitrios, Skandalakis, Panayiotis, and Johnson, Elizabeth O.
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ANATOMICAL variation ,SKULL morphology ,OPERATIVE surgery ,PALATE surgery ,MAXILLA - Abstract
Abstract: Objective: To investigate the anatomical variability of the palatine structures in Greek population. Material and methods: 71 Greek adult dry human skulls were examined to detect the position of the greater palatine (GPF) and lesser palatine foramina (LPF) related to adjacent anatomical landmarks. Results: The perpendicular distance of the GPF to the midline sagittal suture was 1.53cm and 0.3cm from the inner border of the alveolar ridge. The mean distance from the posterior palatal border was consistent 0.46cm on the right and 0.47cm on the left side of the skulls. In the greater majority of the skulls (76.2%), the GPF were between proximal–distal surfaces of the 3rd maxillary molar. A single LPF was observed in 53.45% of the skulls, two LPF were observed in 31% of the skulls bilaterally and five LPF were rare (2.1%). The commonest position of LPF was at the junction of the palatine bone and the inner lamella of the pterygoid plate (71.9%). Conclusion: Our results can help clinicians localize the palatine foramina in patients with and without maxillary molars and to predict the depth of a needle to anaesthetise the maxillary nerve with greater success when performing surgical procedures in the hard and soft palate. [Copyright &y& Elsevier]
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- 2012
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5. Implementing Change in Neuroanatomy Education: Organization, Evolution, and Assessment of a Near-Peer Teaching Program in an Undergraduate Medical School in Greece.
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Karamaroudis S, Poulogiannopoulou E, Sotiropoulos MG, Kalantzis T, and Johnson EO
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- Cross-Sectional Studies, Curriculum, Education, Medical, Undergraduate methods, Educational Measurement statistics & numerical data, Greece, Humans, Learning, Students, Medical statistics & numerical data, Surveys and Questionnaires statistics & numerical data, Education, Medical, Undergraduate organization & administration, Neuroanatomy education, Peer Group, Schools, Medical organization & administration, Teaching organization & administration
- Abstract
In light of the current shifts in medical education from traditional lectures to more active teaching modalities, a peer-teaching program was introduced to a compulsory, second-year neuroanatomy course. A cross-sectional survey of 527 medical students in the six-year medical program of the National and Kapodistrian University of Athens was administered. The primary aim of the survey, which was distributed to second- through sixth-year medical students, who had completed the neuroanatomy course, was to assess student perception of peer teachers (PTs). Across the five years assessed, students increasingly acknowledged the contribution of PTs to their learning (P < 0.001). Attributes of PTs (e.g., contribution to learning, motivation, effective usage of material, and team environment) were significantly related to the student's opinion of the importance of laboratory activities (P < 0.001). Students who received "average" final grades scored the importance of laboratory exercises, and by inference PTs, significantly lower than students who received "excellent" final grades (P < 0.05). The amount of training that PTs had received was also significantly related to student perceptions of a PT's contribution. Better trained PTs were associated with significantly higher scores regarding learning, motivation, and positive environment compared to less trained PTs (P < 0.05). The results of the present study show that peer-teaching was well received by students attending the neuroanatomy course. While the results express the evolution of the program across the years, the findings also show that learners believed that PTs and the laboratory program contributed significantly to their understanding of neuroanatomy., (© 2020 American Association of Anatomists.)
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- 2020
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6. Vesalius criticism on Galen's musculoskeletal anatomy.
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Markatos K, Chytas D, Tsakotos G, Karamanou M, Piagkou M, and Johnson E
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- Belgium, Greece, History, 16th Century, History, Ancient, Anatomy history, Musculoskeletal System anatomy & histology
- Abstract
Galen of Pergamum (129-216/217 AD), an important Greek physician, influenced the history of medicine for more than 1400 years. However, Andreas Vesalius (1514-1564), after performing dissections of human cadavers, remarked that Galen made several mistakes due to the fact that his dissections were on animals, particularly on apes. The current study summarizes the main points in which Vesalius criticized Galen in terms of the musculoskeletal anatomy.
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- 2019
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7. Incidence and morphometry of caroticoclinoid foramina in Greek dry human skulls.
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Efthymiou E, Thanopoulou V, Kozompoli D, Kanellopoulou V, Fratzoglou M, Mytilinaios D, Piagkou M, and Johnson EO
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- Adult, Carotid Artery, Internal surgery, Greece, Humans, Ossification, Heterotopic classification, Ossification, Heterotopic epidemiology, Sphenoid Bone surgery, Carotid Artery, Internal pathology, Ligaments pathology, Ossification, Heterotopic pathology, Sphenoid Bone pathology
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Background: Ossification of the caroticoclinoid ligament (CCL) and formation of a caroticoclinoid foramen (CCF) may impose significant risk to neurosurgeons by impeding mobilization of the cavernous segment of the internal carotid artery. Although safe surgical access to the clinoidal space is related to understanding the CCF anatomical and ethnic variants, there remains a paucity of studies of the morphology and bony relationships. The current study provides a systematic morphological and morphometric analysis of the CCF, the ossification of the CCL extending between the anterior and middle clinoid processes, and their relations in a Greek population., Materials and Methods: The incidence of unilateral and bilateral CCF, types (complete, incomplete, and contact) of ossified CCLs, and foramina diameter according to side and gender were determined in 76 Greek adult dry skulls. Findings were correlated with the morphology of optic strut (OS) (presulcal, sulcal, postsulcal, and asymmetric)., Results: A CCF was detected in 74% of the specimens. The majority of skulls (51.4%) had bilateral CCF, whereas 22.3% of the skulls had unilateral foramina. Incomplete CCF were observed in 69.3%, complete in 19.8%, and contact type in 10.9%. The mean CCF diameter was 0.55 ± 0.07 cm on the left and 0.54 ± 0.08 cm on the right side. Side symmetry existed, although there were no significant differences according to gender. The CCF were more prominent in skulls with a sulcal type of OS., Conclusions: The results of the present study augment the current knowledge on the morphology of key anatomical landmarks, CCF, and CCL ossification in the sellar area, indicating population differences. A significant side asymmetry in caroticoclinoid osseous bridging and foramina is highlighted. These findings are necessary for a safe surgical access to the clinoidal area.
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- 2018
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8. Modernization of an anatomy class: From conceptualization to implementation. A case for integrated multimodal-multidisciplinary teaching.
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Johnson EO, Charchanti AV, and Troupis TG
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- Computer-Assisted Instruction, Curriculum, Dissection, Education, Medical, Undergraduate organization & administration, Educational Measurement, Greece, Humans, Learning, Models, Organizational, Organizational Objectives, Problem-Based Learning, Program Development, Program Evaluation, Students, Medical, Teaching organization & administration, Anatomy education, Cooperative Behavior, Education, Medical, Undergraduate methods, Interdisciplinary Communication, Social Change, Teaching methods
- Abstract
It has become increasingly apparent that no single method for teaching anatomy is able to provide supremacy over another. In an effort to consolidate and enhance learning, a modernized anatomy curriculum was devised by attempting to take advantage of and maximize the benefits from different teaching methods. Both the more traditional approaches to anatomy teaching, as well as modern, innovative educational programs were embraced in a multimodal system implemented over a decade. In this effort, traditional teaching with lectures and dissection was supplemented with models, imaging, computer-assisted learning, problem-based learning through clinical cases, surface anatomy, clinical correlation lectures, peer teaching and team-based learning. Here, we review current thinking in medical education and present our transition from a passive, didactic, highly detailed anatomy course of the past, to a more interactive, as well as functionally and clinically relevant anatomy curriculum over the course of a decade., (Copyright © 2012 American Association of Anatomists.)
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- 2012
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