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In this study, the profile of etoxazole in whole citrus, peel and pulp samples collected from Chongqing, Guangdong and Anhui provinces was monitored and their dietary risk to human had also been assessed. The final residual levels and distributions of etoxazole in citrus samples were detected by using an ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS). The results showed that final concentrations of etoxazole in whole citrus, peel, and pulp were ranged at 0.012–0.174, 0.010–0.637, and 0.010–0.011 mg kg−1, respectively. The assessment of dietary risk suggested that chronic dietary risk of etoxazole in whole fruit and peel were 0.010–0.197% and 0.035–0.951%, respectively. Our findings indicated that the chronic risk of daily consumption of citrus fruit is acceptable at recommended dosage. • The profile of etoxazole in whole citrus, peel and pulp samples was monitored. • The dietary risk of etoxazole in citrus samples to human had been assessed. • Etoxazole residue distributions were peel > whole citrus > pulp. • The chronic risk of daily consumption of citrus is acceptable at recommended dosage. [ABSTRACT FROM AUTHOR]