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This study aimed to evaluate the association between occupational radiation exposure and changes in thyroid hormone levels among medical radiation workers. This retrospective cohort study included 2,946 radiation workers from 20 Guangzhou hospitals. Data on general characteristics, participant radiation dosimetry, and thyroid function test results [thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroid hormone (T4)] were extracted from dosimetry and medical records. The generalized estimating equation was used to evaluate the trend of changes in thyroid hormone levels over time and was adjusted for age, gender, and occupation. The average annual effective dose was very low and showed a general downward trend. During the follow-up period, changes in T3 and T4 levels among radiation workers were –0.015 [95% confidence interval (CI) −0.018 to −0.012] nmol/L per year and −2.294 (95% CI −2.426 to −2.162) nmol/L per year, respectively. Thyroid hormone levels were significantly different between males and females. T3 levels in the group of upper quartile of dose were significantly higher than in the lower quartile group (P = 0.006). No significant decreased trend in thyroid hormone levels was observed with increasing average effective doses. Thyroid hormone secretion might be affected even in low-dose radiation exposure environments. [ABSTRACT FROM AUTHOR]

Invited for this month's cover is the group of Dr. Mihail Barboiu from the Institut Europeen des Membranes of Montpellier, France and the Lehn Institute of Functional Materials at Sun‐yat Sen University in Guangzhou, China. The cover picture shows the molecular recognition of folded 1,ω‐amino‐acids guests withinp‐sulfonatocalix[4]arene host anions stabilized with alternating hydrated cations and water molecules. Read the full text of the article at 10.1002/cplu.202000232. [ABSTRACT FROM AUTHOR]