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BACKGROUND: Leprosy, Hansen's disease, is a chronic granulomatous infectious disease caused by Mycobacterium leprae. It is a slowly progressive, chronic infectious disease which mainly affects peripheral nerve and skin. AIMS AND OBJECTIVES: This article aims to study the various histological types of leprosy in a tertiary care hospital. MATERIALS AND METHODS: It was a retrospective study carried out from January 2021 to September 2023. A series of 109 clinically suspected skin lesions of leprosy were examined histopathologically. RESULTS: In our study, out of the 109 cases the most common histopathological type of leprosy was borderline tuberculoid i.e. 43 cases (39.4%). 2nd most common type in our study was tuberculoid type which included 16 cases (14.6%). Borderline borderline type had 11 cases (10.0%), lepromatous type 14 cases (12.8%), indeterminate 14 cases (12.8%) and histoid type 2 cases (1.8%). CONCLUSION: The spectrum of leprosy presentation is very wide. The findings in our study were more common in males and present mostly in the 21 to 40 years of life. Most common histopathological finding was borderline tuberculoid type. [ABSTRACT FROM AUTHOR]