1. Uncommon Bis‐quinolizidine Alkaloids from the Hainan Sponge Neopetrosia chaliniformis.
- Author
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Chen, Bao Please confirm that given names (blue) and surnames/family names (vermilion) have been identified correctly. -->, Huan, Xia‐Juan, Miao, Ze‐Hong, Voogd, Nicole J., Gu, Yu‐Cheng, Wang, Chang‐Yun, Guo, Yue‐Wei, and Li, Xu‐Wen
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SPONGES (Invertebrates) ,BIOLOGICAL assay - Abstract
Main observation and conclusion: Two new bis‐quinolizidine alkaloids, neopetrosiasins A (1) and B (2), possessing cis‐ and trans‐quinolizidine nuclei, one known related analogue petrosin (3) and three known xestospongins (4—6), were isolated from the South China Sea sponge Neopetrosia chaliniformis. The structures of new compounds were unambiguously determined by extensive spectroscopic and single‐crystal X‐ray analyses. In bioassay, compounds 4—6 exhibited moderate cytotoxicity against several human cancer cells. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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