1. Corneal endothelial cell density and morphology in healthy Chinese eyes.
- Author
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Yunliang S, Yuqiang H, Ying-Peng L, Ming-Zhi Z, Lam DS, and Rao SK
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Cell Count, Child, Female, Hong Kong, Humans, Male, Middle Aged, Prospective Studies, Reference Values, Sex Distribution, Sex Factors, Asian People, Endothelium, Corneal cytology
- Abstract
Purpose: To describe corneal endothelial cell density and morphology in healthy Chinese eyes., Methods: Specular microscopy was performed in 1329 eyes of 700 healthy volunteers (M:F, 311:389), 10 to 98 years of age. Parameters studied included endothelial cell density (CD), cell area (CA), coefficient of variation (CV) in cell area, and percent hexagonality., Results: Mean endothelial CD in the study population was 2932 +/- 363 cells/mm2. There was a statistically significant decrease in endothelial CD (P < 0.001; correlation, -0.435) and percentage of hexagonal cells (P < 0.001; correlation, -0.241) with age. Mean CA, CV, and percentage of hexagonal cells were 347 +/- 46 microm2, 33 +/- 5, and 59% +/- 9%, respectively. There was also a statistically significant increase in CA (P < 0.001; correlation, 0.410) and CV (P < 0.001; correlation, 0.251) with increasing age., Conclusions: Normative data for the endothelium in the Chinese population are reported. Our data add to the knowledge about endothelial cell parameters in Chinese eyes and serve as a baseline for comparative studies with other populations.
- Published
- 2007
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