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Reports on the successful use of the p53 gene in the suppression of tumors in head and neck cancers of patients at the M.D. Anderson Cancer Center in Houston, Texas. Injection of viruses carrying copies of p53 into patient's tumors; Plan for bigger trials.

Reports that the U.S. Patent and Trademark Office has issued a patent to the Board of Regents of the University of Texas System for '1-Methoxyestradiol-induced apoptosis in cancer cells,' according to Introgen Therapeutics Inc. and The University of Texas M.D. Anderson Cancer Center, Houston.

Studies the mice with p53, an antioncogene and best studied protein as the natural defense of the body against cancer at the Baylor College of Medicine in the United States. Team of researchers led by Lawrence A. Donehower, professor of molecular virology and microbiology; Findings on mice with p53; Side effects of the natural safeguards.