1. Normal reference values of low frequency specific air-conducted auditory brainstem responses among normal hearing children of different ages: A retrospective observational study.
- Author
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Wang, Xiaohua, Xia, Zhongfang, and Hu, Yanling
- Subjects
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REFERENCE values , *BRAIN stem , *AGE groups , *NEWBORN infants , *SCIENTIFIC observation - Abstract
To explore and compare the normal reference values (NRV) for low frequency specific air-conducted tone-burst auditory brainstem response (tb-ABR) among children of different ages and with normal hearing, because tb-ABR is often used to supplement the lack of click-evoked ABR (click-ABR) frequency but the NRV of this response threshold in different populations remain inconclusive. This retrospective observational study included children younger than 5 years of age with normal hearing in Hubei Province between November 2020 and September 2021. These children came to center of audiology for audiological examination including click-ABR due to different purposes and had accepted suggestion of tb-ABR test (0.5 kHz, 1 kHz). The children were divided into 5 groups according to age (0–12, 13–24, 25–36, 37–48, and 49–60 months of age), and 20 children (40 ears) met the inclusion criteria were selected from each group. The responding thresholds, peak latencies (PL), and inter-peak latencies (IPL) of the major waves were counted and compared in each group. NRV of responding thresholds (dBnHL) in children aged 0–12, 13–24, 25–36, 37–48, and 49–60 months were 27.25 ± 9.47, 22.63 ± 5.31, 21.5 ± 5.33, 18.25 ± 5.83, and 21.63 ± 6.24 at 0.5 kHz, and 23.63 ± 7.16, 20.88 ± 7.06, 22 ± 4.21, 17.75 ± 6.09, and 21.38 ± 4.53 at 1 kHz, respectively. The response thresholds of children aged 0–12 months were significantly higher compared to children in other age groups at 0.5 kHz (all P < 0.05) and significantly higher than in children aged 37–48 months at 1 kHz (P < 0.05). There were significant differences among children of different ages in Wave III (P < 0.001) and Wave V (P < 0.001) in the peak latencies, and Waves I-III (P = 0.003) and Waves I–V (P < 0.001) in the inter-peak latencies at 0.5 kHz. Also, there were significant differences among children of different ages in Wave III and Wave V in the PL, and Waves I-III, Waves III-V, and Waves I–V in the IPL at 1 kHz (all P < 0.001). The NRV of tb-ABR at 0.5 kHz and 1 kHz might differ among children of different ages. Newborn infants (<12 months old) might have a higher response threshold, while children aged 37–48 months might have a lower response threshold. However, it was a retrospective analysis with a small sample size, prospective contrast studies with larger samples are needed in the future. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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