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Landslide susceptibility denotes the likelihood of a disaster event under specific conditions. The assessment of landslide susceptibility has transitioned from qualitative to quantitative methods. With the integration of information technology in geological hazard analysis, a range of quantitative models for assessing landslide susceptibility has emerged and is now widely used. To compare and evaluate the accuracy of these models, this study focuses on Xupu County in Hunan Province, applying several models, including the CF model, FR model, CF-LR coupled model, FR-LR coupled model, SVM model, and RF model, to assess regional landslide susceptibility. ROC curves are used to evaluate the reliability of the model's predictions. The evaluation results reveal that the CF model (AUC = 0.756), FR model (AUC = 0.764), CF-LR model (AUC = 0.776), FR-LR model (AUC = 0.781), SVM model (AUC = 0.814), and RF model (AUC = 0.912) all have AUC values within the range of 0.7–0.9, indicating that the overall accuracy of the models is good and can provide a reference for landslide susceptibility zoning in the study area. Among these, the Random Forest model demonstrates the best accuracy for landslide susceptibility zoning in the study area. By extracting the extremely high susceptibility zones from the landslide susceptibility zonings obtained by six models, a comparative analysis of model adaptability was conducted. The results indicate that the Random Forest model has the best adaptability under specific conditions in Xupu County. [ABSTRACT FROM AUTHOR]