1. Survival and early complications of preterm infants with birthweight less than 500 grams during a 10-year period in Hungary.
- Author
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Varga P, Berecz B, Magyar Z, Pete B, Romicsné Görbe É, Dombi ZA, Sassi L, Fanczal E, Ács N, Kornya L, Joó JG, Valek A, Harmath Á, and Gasparics Á
- Subjects
- Adult, Apgar Score, Bronchopulmonary Dysplasia epidemiology, Cerebral Intraventricular Hemorrhage epidemiology, Enterocolitis, Necrotizing epidemiology, Female, Humans, Hungary epidemiology, Infant, Extremely Low Birth Weight, Infant, Extremely Premature, Infant, Newborn, Leukomalacia, Periventricular epidemiology, Mortality trends, Multiple Birth Offspring statistics & numerical data, Pregnancy, Prenatal Care, Retinopathy of Prematurity epidemiology, Cesarean Section statistics & numerical data, Glucocorticoids therapeutic use, Pulmonary Surfactants therapeutic use, Survival Rate trends
- Abstract
Background: There are limited data available on the survival and early complications of preterm infants with less than 500 g birthweight. To estimate the outcomes for these infants, it is important for caregivers to be aware of perinatal factors that may affect survival., Objectives: We assessed the mortality and certain early complications of preterm infants born with less than 500 g in Hungary between 2006 and 2015., Methods: We reviewed data of 486 infants from the database of the Hungarian Central Statistical Office and in parallel of 407 infants from the "NICU database." The study period was divided into two epochs: 2006-2010 and 2011-2015., Results: The survival was 27.1% in the first epoch and 39.1% in the second epoch, and the incidence of early complications was slightly higher in the second epoch. In the surviving group (first and second epoch combined), gestational age (25.1 vs 23.7 weeks), birthweight (458 vs 447 g) antenatal steroid treatment (66.3% vs 52.3%), surfactant therapy (95.1% vs 84.3%), median Apgar scores (6 vs 3 and 8 vs 5 at 1 and 5 minutes, respectively) and proportion of caesarean delivery (89.3% versus 68.5%) were higher than in the non-surviving group (first and second epoch combined). The proportion of multiple births was lower in the surviving group (15.7% vs 33.4%)., Conclusions: Survival of infants with less than 500 g improved between 2006-2010 and 2011-2015 in Hungary. The slightly higher occurrence of early complications might be associated with improving survival., (© 2019 The Authors. Paediatric and Perinatal Epidemiology Published by John Wiley & Sons Ltd.)
- Published
- 2020
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