1. Circulation of Third-Generation Cephalosporin Resistant Salmonella Typhi in Mumbai, India.
- Author
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Argimón, Silvia, Nagaraj, Geetha, Shamanna, Varun, Sravani, Dharmavaram, Vasanth, Ashwini Kodlipet, Prasanna, Akshatha, Poojary, Aruna, Bari, Anurag Kumar, Underwood, Anthony, Kekre, Mihir, Baker, Stephen, Aanensen, David M, and Lingegowda, Ravikumar Kadahalli
- Subjects
GENETIC mutation ,FLUOROQUINOLONES ,TYPHOID fever ,THIRD generation cephalosporins ,SALMONELLA ,BETA lactamases ,DRUG resistance in microorganisms ,MICROBIAL sensitivity tests - Abstract
We report the persistent circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, linked to the acquisition and maintenance of a previously characterized IncX3 plasmid carrying the ESBL gene bla
SHV-12 and the fluoroquinolone resistance gene qnrB7 in the genetic context of a triple mutant also associated with fluoroquinolone resistance. [ABSTRACT FROM AUTHOR]- Published
- 2022
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