1. First case of subcutaneous zygomycosis caused by Saksenaea vasiformis in India.
- Author
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Padhye AA, Koshi G, Anandi V, Ponniah J, Sitaram V, Jacob M, Mathai R, Ajello L, and Chandler FW
- Subjects
- Adult, Amputation, Surgical, Foot Dermatoses epidemiology, Foot Dermatoses pathology, Foot Dermatoses therapy, Humans, India, Male, Mucormycosis epidemiology, Mucormycosis pathology, Mucormycosis therapy, Potassium Iodide adverse effects, Potassium Iodide therapeutic use, Foot Dermatoses etiology, Mucormycosis etiology
- Abstract
The first case of subcutaneous zygomycotic infection caused by Saksenaea vasiformis in a rice mill worker from India is described. The infection, confined to the man's left foot, showed multiple draining sinuses, inflammation, and intermittent low-grade fever following a crushing injury when a log fell on his foot. Histopathologic examination of two biopsy specimens, taken at 3-wk intervals, revealed the presence of broad, sparsely septate, branched, hyaline hyphae characteristic of a zygomycete. When they were grown on a nutritionally deficient medium, two cultures isolated from the biopsied tissues formed numerous, vase-shaped sporangia typical of S. vasiformis. Necrosis of the affected area led to amputation of the fore part of the foot. A split thickness graft was well accepted, and treatment with potassium iodide, following the graft, cured the infection.
- Published
- 1988
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