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Aim Hypertension ( HTN) and chronic kidney disease ( CKD) are important emerging problems in low-income countries, with an increasing number of patients dying from their consequences. Methods A project for investigating these issues was carried out in West Bengal, India, in 2536 adult subjects. Body mass index ( BMI) was classified using traditional and new cut-offs identified by the World Health Organization for Asian populations. HTN was classified according to the Joint National Committee 7 and CKD according to presence of estimated glomerular filtration rate ( eGFR) of less than 60 mL/min per 1.73 m2. Results Normal BMI ( Asian reference) was found in 41.5% of subjects, while 33.4% were underweight, 19.3% overweight and 5.8% obese. Prevalence of stage 1 and 2 HTN was 39.4%. Proteinuria (urine dipstick >1+) was present in 7.7% of the sample. In a subsample of 1526 subjects, e GFR of less than 60 mL/min per 1.73 m2 was found in 4.2%. At multivariate analysis, factors associated with HTN were weight classes ( P < 0.001), presence of proteinuria ( P < 0.001) and family history of HTN ( P = 0.028), while living in rural areas was associated with lower risk for HTN ( P = 0.003). e GFR was inversely related to BMI ( P = 0.03), the presence of proteinuria ( P < 0.001) and HTN ( P < 0.003), and directly related to living in rural areas ( P = 0.003). Conclusion High prevalence of HTN was found in subjects with very limited access to health care in West Bengal. HTN was more common in overweight individuals, but also affected normal weight and underweight subjects in a significant part of the tested population. Preventive medicine should be a strong priority in this setting. [ABSTRACT FROM AUTHOR]

Background: Childhood hypertension is an established predictor of adult hypertension and organ damage, an underestimated problem in developing countries. The aim of the study was to assess the prevalence of arterial hypertension, as well as the relationship of blood pressure values and weight class and urinary abnormalities in 1176 children (aged 5-12 years) from a suburban area south of Kolkata, India., Method: Arterial blood pressure, height, weight and waist circumference were measured. Weight class was defined according to the tables of the International Obesity Task Force. Urinalysis was performed with reagent strips to detect glucosuria, microhematuria and proteinuria., Results: The majority of children (74.7%) were underweight and 5.2% had systolic and/or diastolic blood pressure values higher or equal to the 95th percentile, according to the National High Blood Pressure Education Program normograms. Hypertension had a high prevalence both in underweight children (4.3%) and in normal-weight children (6.9%) and significantly increased in the rare overweight children (4/20, 20%). A fraction of 8.5% of hypertensive children had urinary abnormalities (microhematuria only) vs. 12.5% in nonhypertensive children (P value 0.36)., Conclusion: Prevalence of hypertension in North-Eastern Indian children is higher than in Western countries and only partly associated to weight class. Causes of hypertension do not seem to be related to overt kidney disease and remain to be elucidated.