1. Effect of Implantations of Coated and Uncoated Implants in Rabbit Bone Tissue Regeneration: An In-vivo Study.
- Author
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Chakrabarty, Abhijit, Kumar Kundu, Dibyendu, Choudhuri, Saumya Roy, Das, Goutam, Ghosh, Sudipta, Badr, Jawaid, Mukherjee, Mekhala, and Bhattacharya, Arkamita
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BONE regeneration , *EDENTULOUS mouth , *ENERGY dispersive X-ray spectroscopy , *IN vivo studies , *STOMATOGNATHIC system , *GLASS coatings - Abstract
Introduction: The goal of present day dentistry is to rehabilitate the functional stomatognathic system, of a patient to a normal contour, function, comfort and aesthetics regardless of the atrophy, injury or disease of the functional system. A novel dental implant system provides ideal functional and aesthetic rehabilitation of the edentulous jaw. Prior to the design and use of a newly developed implant in humans, it is necessary to evaluate the performance of two varieties each of the uncoated implants and the implants coated with bio-ceramic Hydroxyapatite (HAP), and bio-active glass in terms of their capability to enhance the tissue regeneration at the implanted sites in animal model. In this presentation, two sets of studies were done on rabbits, to determine the osseous regeneration capability in relation to the in-vivo situation. Aim: The first study was done to study the effects of the following in bony tissue regeneration: a) Ti (screw) implant macro design vis-àvis b) Ti (smooth) implant and also c) HAP powder as a filler material. In the second study, four coated implant systems, specifically HAP or bio-active glass coated, Ti (smooth) and Ti (screw) implants have been considered and their relationship with surrounding hard tissues have been observed. Materials and Methods: An in-vivo study was conducted in the Department of Periodontics, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India in 2015. For the implantation studies on rabbits, the implants were placed into the drilled hole socket of the mid-metaphyseal region of their hind legs. After 3 months, the rabbits were sacrificed and the implanted sites were investigated with Scanning Electron Microscopy (SEM) with Energy Dispersive X-ray Analysis (EDX), histopathological tests and push-out tests to obtain some conclusive analysis of the bony tissue regeneration using the implant design modification, without or with the two proposed coatings. Results: Results showed that the effectiveness of the bio-active coatings, are more in the case of Ti (screw) implant design, as compared to the Ti (smooth) implants. Conclusion: The observations also established that, the HAP coated Ti (screw) implant is more effective than the bio-active glass coated Ti (screw) implant, specifically in terms of bone to implant contact and interfacial strength. [ABSTRACT FROM AUTHOR]
- Published
- 2024