1. Ascomycotin A, a new citromycetin analogue produced by Ascomycota sp. Ind19F07 isolated from deep sea sediment.
- Author
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Tian YQ, Lin XP, Liu J, Kaliyaperumal K, Ai W, Ju ZR, Yang B, Wang J, Yang XW, and Liu Y
- Subjects
- Anti-Bacterial Agents isolation & purification, Geologic Sediments microbiology, Heterocyclic Compounds, 3-Ring isolation & purification, Indian Ocean, Molecular Structure, Pyrones isolation & purification, Anti-Bacterial Agents chemistry, Ascomycota chemistry, Heterocyclic Compounds, 3-Ring chemistry, Pyrones chemistry
- Abstract
A new citromycetin analogue, ascomycotin A (1), together with eight known compounds, wortmannilactone E (2), orcinol (3), orsellinic acid (4), isosclerone (5), (3R,4S)-( - )-4-hydroxymellein (6), diorcinol (7), chaetocyclinone B (8) and 2,5-dimethoxy-3,6-di(p-methoxypheny1)-1,4-benzoquinone (9), was isolated from the fungal strain Ascomycota sp. Ind19F07, which was isolated from the deep sea sediment of the Indian Ocean. The structures of the compounds were established by spectroscopic data including 1D and 2D NMR and HR-ESI-MS. Compounds (1-9) were evaluated for antibacterial activity.
- Published
- 2015
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