1. Inguinal hernia repair with porcine small intestine submucosa: 3-year follow-up results of a randomized controlled trial of Lichtenstein's repair with polypropylene mesh versus Surgisis Inguinal Hernia Matrix
- Author
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Ansaloni, Luca, Catena, Fausto, Coccolini, Federico, Gazzotti, Filippo, D'Alessandro, Luigi, and Pinna, Antonio Daniele
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INGUINAL hernia , *IMMUNOGENETICS , *POLYPROPYLENE , *DISEASE relapse , *TREATMENT effectiveness , *MEDICAL polymers , *PAIN management ,GROIN surgery - Abstract
Abstract: Background: The aim of this study was to evaluate the safety and efficacy of Lichtenstein''s hernioplasty using Surgisis Inguinal Hernia Matrix (SIHM; Cook, Bloomington, Indiana) compared with polypropylene (PP; Angiologica, Pavia, Italy). Methods: This was a prospective, randomized, double-blind trial comparing Lichtenstein''s inguinal hernioplasty using SIHM versus PP. Results: Seventy male patients underwent Lichtenstein''s hernioplasty (n = 35 in the SIHM group and n = 35 in the PP group). At 3 years after surgery, there were 2 deaths (5.7%) in the PP group and 1 death (2.9%) in the SIHM group (not significant [NS]). Although the study was underpowered to evaluate the recurrence rate, only 1 recurrence (2.9%) was seen in the PP group (NS). Although a significant decrease in postsurgical pain incidence was never observed among patients in the SIHM group, a significantly lower degree of pain was detected at rest and on coughing at 1, 3, and 6 months and on movement at 1, 3, and 6 months and 1, 2, and 3 years. A significant decrease in postsurgical incidence and degree of discomfort when coughing and moving were observed among patients in the SIHM group at 3 and 6 months and at 1, 2, and 3 years after surgery. Comments: SIHM hernioplasty seems to be a safe and effective procedure. [Copyright &y& Elsevier]
- Published
- 2009
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