1. Investigating the effectiveness of PHR-160 spray in controlling and improving the symptoms of patients with covid-19 - A multicenter, double-blind, randomized clinical trial study.
- Author
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Mohtashami, Reza, Raei, Mehdi, Bagheri, Mahdi, Shahriary, Alireza, Goodarzi, Hassan, Soodmand, Mostafa, and Rezae, Milad Asghardoust
- Subjects
DRUG efficacy ,RESEARCH ,COVID-19 ,ACADEMIC medical centers ,TREATMENT effectiveness ,NEBULIZERS & vaporizers ,RANDOMIZED controlled trials ,BLIND experiment ,STATISTICAL sampling - Abstract
Background: One of the recommended treatment methods for covid-19 is herbal treatments, which, if used, can be used as an effective preventive or supportive treatment in the treatment plan of patients with covid-19. PHR160 spray is a combination of cineole, menthol, Safran, safranal, and crocin each of these substances affects respiratory diseases alone. Aim: Investigating the effectiveness of PHR-160 spray, in the treatment of Covid-19. Methods: The present study is a multicenter, double-blind, randomized clinical trial study, which was conducted in 4 medical centers. The study population includes all hospitalized patients with covid-19 who met the study inclusion criteria. The data collection tool was a checklist including 1- demographic information, 2- vital signs, symptoms, CT scan changes, and drug side effects (neural, cardiac, and respiratory) at the beginning of admission and from the first to the 10th day. Result: There was no significant difference between the intervention and control groups in the study of demographic variables, vital signs, symptoms, CT scan changes, and drug side effects before using PHR-160 spray (P>0.05). Also, after using PHR-160 spray for ten days, there was no significant difference in the admission to the intensive care unit, and patient mortality in the two groups (P>0.05) Conclusion: Based on the results, PHR-160 spray has no beneficial effects in controlling the symptoms of patients with covid-19 and cannot play an effective role in improving the patient's condition and reducing the complications caused by the disease. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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