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Background: There are few data available to health care providers regarding the costs of treating patients with psoriasis, and specifically the cost of phototherapy., Objectives: As narrowband UVB (TL-01) has now become an established therapy for patients with psoriasis requiring phototherapy, we determined the annual cost of delivering TL-01 treatment in a university hospital., Methods: The costing evaluation was from a hospital perspective and the strategy used was a microcosting detailed collection of resources used., Results: The annual cost of TL-01 treatment in our teaching hospital was 53,555.00 euros. Staffing accounted for 70% of the cost. The average individual costs were 325.00 euros (range: 57.20-972.40)., Conclusion: These costs are significant but remain less expensive than inpatient treatment.