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Our capability to accurately predict at the local scale the morphological changes in a mountain river affected by a severe flood is currently limited. Given the importance of including geomorphological hazards in flood risk evaluation, some improvements in this direction are required. In fact, on the basis of the controlling factors typically considered in the literature, that are the unit stream power (ω pk) and the confinement index (CI), a relatively broad spectrum of width ratios (WR = ratio between channel width after a flood and channel width before a flood) occurring in response to major floods is commonly observed in streams. We extended previous research focused on parameters that influence the morphological response of a channel to a severe flood by investigating the role played by the type of sediment transport process that occurs in a mountain river. In particular, we explored whether a relationship exists between debris flood (i.e. a condition characterised by extremely high bedload) and intense channel widening. The case study was the Cordevole River (the Dolomites, Italy) and four of its tributaries, which were affected by the severe flooding induced by the Vaia storm in October 2018. WR was determined at the sub-reach scale, and ω pk was calculated with consideration for the flood peak discharge ascertained via hydrological modeling. Despite the significant relationships found among WR, ω pk and CI, 21 sub-reaches (out of 144) of the studied stream network widened intensely reaching a WR higher than approximately 4, often to a substantially larger extent than predicted by statistical models. Such sub-reaches were certainly or probably affected by debris floods, leading us to infer that debris floods can induce widening processes that are more intense than those occurring in response to water flows. Having said that, debris floods do not automatically imply very intense widening. In addition to hydraulic and morphological constraints, the sediment transport processes possibly taking place at a sub-reach of a mountain river should be regarded as another driver of channel modifications during high-magnitude hydrological events. • Intense widening occurred along mountain rivers in response to a large flood. • Different types of fluid gravity flow drive various morphological channel responses. • Debris flood can induce more intense widening than that caused by water flow. [ABSTRACT FROM AUTHOR]

On 24 August 2006, a debris flow took place in the Moscardo Torrent, a basin of the Eastern Italian Alps instrumented for debris-flow monitoring. The debris flow was recorded by two seismic networks located in the lower part of the basin and on the alluvial fan, respectively. The event was also recorded by a pair of ultrasonic sensors installed on the fan, close to the lower seismic network. The comparison between the different recordings outlines particular features of the August 2006 debris flow, different from that of events recorded in previous years. A typical debris-flow wave was observed at the upper seismic network, with a main front abruptly appearing in the torrent, followed by a gradual decrease of flow height. On the contrary, on the alluvial fan the wave displayed an irregular pattern, with low flow depth and the main peak occurring in the central part of the surge both in the seismic recording and in the hydrographs. Recorded data and field evidences indicate that the surge observed on the alluvial fan was not a debris flow, and probably consisted in a water surge laden with fine to medium-sized sediment. The change in shape and characteristics of the wave can be ascribed to the attenuation of the surge caused by the torrent control works implemented in the lower basin during the last years. [ABSTRACT FROM AUTHOR]

Alluvial fans are often present at the outlet of small drainage basins in alpine valleys; their formation is due to sediment transport associated with flash floods and debris flows. Alluvial fans are preferred sites for human settlements and are frequently crossed by transport routes. In order to reduce the risk for economic activities located on or near the fan and prevent loss of lives due to floods and debris flows, torrent control works have been extensively carried out on many alpine alluvial fans. Hazard management on alluvial fans in alpine regions is dependent upon reliable procedures to evaluate variations in the frequency and severity of hydrogeomorphic processes and the long-term performance of the torrent training works. An integrated approach to the analysis of hydrogeomorphic processes and their interactions with torrent control works has been applied to a large alluvial fan in the southern Carnic Alps (northeastern Italy). Study methods encompass field observations, interpretation of aerial photographs, analysis of historical documents, and numerical modelling of debris flows. The overall performance of control works implemented in the early decades of 20th century was satisfactory, and a reduction of hazardous events was recognised from features observed in the field and in aerial photographs, as well as from the analysis of historical records. The 2-D simulation of debris flows confirms these findings, indicating that debris flow deposition would not affect urban areas or main roads, even in the case of a high-magnitude event. Present issues in the management of the studied alluvial fan are representative of situations frequently found in the European Alps and deal with the need for maintenance of the control structures and the pressures for land use changes aimed at the economic exploitation of the fan surface. [ABSTRACT FROM AUTHOR]

High-resolution topographic data expand the potential of quantitative analysis of the earth surface, improving the interpretation of geomorphic processes. In particular, the morphologies of the channel beds of mountain streams, which are characterised by strong spatial variability, can be analysed much more effectively with this type of data. In this study, we analysed the aerial LiDAR topographic data of a headwater stream, the Rio Cordon (watershed area: 5 km2), located in the Dolomites (north-eastern Italy). The morphology of the channel bed of Rio Cordon is characterised by alternating step pools, cascades, and rapids with steps. We analysed the streambed morphology by means of ad hoc developed morphometric indices, capable of highlighting morphological features at a high level of spatial resolution. To perform the analysis and the data interpolation, we carried out a channel-oriented coordinate transformation. In the new coordinate system, the calculation of morphometric indices in directions along and transverse to the flow direction is straightforward. Three geomorphometric indices were developed and applied as follows: a slope index computed on the whole width of the channel bed, directional variograms computed along the flow direction and perpendicular to it, and local anomalies, calculated as the difference between directional variograms at different spatial scales. Directional variograms in the flow direction and local anomalies have proven to be effective at recognising morphologic units, such as steps, pools and clusters of large boulders. At the spatial scale of channel reaches, these indices have demonstrated a satisfactory capability to outline patterns associated with boulder cascades and rapids with steps, whereas they did not clearly differentiate between morphologies with less marked morphological differences, such as step pools and cascades. [ABSTRACT FROM AUTHOR]

Monitoring of debris flows aimed to the assessment of their physical parameters is very important both for theoretical and practical purposes. Peak discharge and total volume of debris flows are crucial for designing effective countermeasures in many populated mountain areas where losses of lives and property damage could be avoided. This study quantifies the relationship between flow depth, acoustic amplitude of debris flow induced ground vibrations and front velocity in the experimental catchment of Acquabona, Eastern Dolomites, Italy. The analysis of data brought about the results described in the following. Debris flow depth and amplitude of the flow-induced ground vibrations show a good positive correlation. Estimation of both mean front velocity and peak discharge can be simply obtained monitoring the ground vibrations, through geophones installed close to the flow channel; the total volume of debris flow can be so directly estimated from the integral of the ground vibrations using a regression line. The application of acoustic technique to debris flow monitoring seems to be of the outmost relevance in risk reduction policies and in the correct management of the territory. Moreover this estimation is possible in other catchments producing debris flows of similar characteristics by means of their acoustic characterisation through quick and simple field tests (Standard Penetration Tests and seismic refraction surveys). [ABSTRACT FROM AUTHOR]

Faccini et al. (2012) describe an intense rainstorm that caused a flash flood and triggered landslides in a sector of Eastern Liguria (Italy) on 1 June 2007 and discuss the implications for geomorphic hazard assessment and land use planning. This comment points out some weaknesses in the use of weather radar for the assessment of rainfall and in the documentation of flood response. [ABSTRACT FROM AUTHOR]

A model for the analysis of topographic influence on shallow landslide initiation is applied to an experimental mountain basin where high-resolution digital elevation data are available: the Cordon catchment (5 km2) located in northern Italy. The model delineates those areas most prone to shallow landsliding due to surface topographic effects on hydrologic response. The model is composed of two parts: a steady-state model for shallow sub-surface runoff and an infinite-slope Coulomb failure model which assumes that the soil is cohesionless at failure. An inventory of landslide scars is used to document sites of instability and to provide a test of model performance by comparing observed landslide locations with model predictions. The model reproduces the observed distribution of landslide locations in a consistent way, although spatial variations in soil strength and transmissivity, which are not accounted for in the model, influence specific distribution of landslide areas within regions of similar topographic control. [ABSTRACT FROM AUTHOR]

Large floods may produce remarkable channel changes, which determine damages and casualties in inhabited areas. However, our knowledge of such processes remains poor, as is our capability to predict them. This study analyses the geomorphic response of the Nure River (northern Italy) and nine tributaries to a high-magnitude flood that occurred in September 2015. The adopted multi-disciplinary approach encompassed: (i) hydrological and hydraulic analysis; (ii) analysis of sediment delivery to the stream network by means of landslides mapping; (iii) assessment of morphological modifications of the channels, including both channel width and bed elevation changes. The spatial distribution of rainfall showed that the largest rainfall amounts occur in the upper portions of the catchment, with cumulative rainfall reaching 300 mm in 12 h, and recurrence intervals exceeding 100–150 years. The unit peak discharge ranged between 5.2 and 25 m 3  s −1  km −2 . Channel widening was the most evident effect. In the tributaries, the ratio between post-flood and pre-flood channel width averaged 3.3, with a maximum approaching 20. Widening was associated with channel aggradation up to 1.5 m and removal of riparian vegetation. New islands formed due to the fragmentation of the former floodplain. In the Nure River, the average width ratio was 1.7, and here widening occurred mainly at the expenses of islands. Bed level dynamics in the Nure were varied, including aggradation, incision, and overall stability. The flood geomorphic effectiveness was more pronounced in the middle-higher portions of the basin. Planimetric and elevation changes were well correlated. Regression analysis of the relationship between widening and morphological/ hydraulic controlling factors indicated that unit stream power and confinement index were the most relevant variables. The study provides useful insights for river management, especially with regard to the proportion of the valley floor subject to erosion and/or deposition during large events. [ABSTRACT FROM AUTHOR]

Summary: Coarse sediment transport processes in steep headwater streams may vary between bedload and debris flows events, depending on basin geomorphology and sediment supply. This paper compares two small catchments (drainage area 4–5km2) located in the Eastern Italian Alps where the dominant sediment transport processes differ substantially, i.e., debris flows in the Moscardo Torrent and bedload events in the Rio Cordon. The two basins were selected because they provided the unique opportunity to analyze long-term data of debris flow and bedload volumes, respectively. The two basins are compared in terms of peak discharge, event duration, and magnitude–frequency characteristics of transported sediment volumes. Additional bedload data from two more Alpine experimental basins are also considered. The results show that, for comparable recurrence intervals, debris flow volumes are 2–3 orders of magnitude larger than bedload volumes. This contrasting sediment transfer activity can be attributed to different basin and channel morphologies, which are analyzed in terms of sediment supply conditions, longitudinal profiles and slope–area curves. [Copyright &y& Elsevier]

The ability to observe the world has seen significant developments in the last few decades, alongside the techniques and methodologies to derive accurate digital replicas of observed environments. Underwater ecosystems present greater challenges and remain largely unexplored, but the need for reliable and up-to-date information motivated the birth of the Interreg Italy-Croatia SUSHI DROP Project (SUstainable fiSHeries wIth DROnes data Processing). The aim of the project is to map ecosystems for sustainable fishing and to achieve this goal a prototype of an Unmanned Underwater Vehicle (UUV), named Blucy, has been designed and developed. Blucy was deployed during project missions for surveying the benthic zone in deep waters of the Adriatic Sea with non-invasive techniques compared to the use of trawl nets. This article describes the strategies followed, the instruments applied and the challenges to be overcome to obtain an accurately georeferenced underwater survey with the goal of creating a marine digital twin.

The transmission of antimicrobial resistance bacteria from animals to humans has become an important concern. The extended-spectrum beta-lactamase (ESBL) -AmpC- producing Escherichia coli (ESBL-AmpC EC) and quinolones resistant E. coli are of particular interest. The present study aimed to evaluate the load and prevalence of antibiotic-resistant commensal E. coli along the goose production cycle on 2 free-range farms in central Italy. On A farm, oxytetracycline was administered, while the B farm did not use antibiotics during the geese productive cycle. One hundred geese of 1-day-old from the same batch were divided into the two farms. At hatching, the animals showed an average of E. coli loads was 6.83 ± 0.48 log CFU/g, and 0.28 ± 0.28, 0, 5.12 ± 0.54 log CFU/g for E. coli resistant to nalidixic acid (E. coli nal ), to cefotaxime (E. coli cef ) and to tetracyclines (E. coli tet ), respectively. The loads of E. coli, E. coli nal , E. coli cef and E. coli tet on 224 environmental faecal pools were determined at 8 time points. Antimicrobial susceptibility and molecular characterization of E. coli cef isolates were performed. The ANOVA was used to assess the difference in bacterial loads between the two farms. We described more than 50% of resistances for tetracyclines in both farms, and sulphonamides and cephazolin in the A farm. The loads of E. coli and E. coli nal in faeces were estimated at approximately 6-7 log (CFU/g) and 5-6 log (CFU/g) in the two farms, respectively. The average load of extended-spectrum beta-lactamase Escherichia coli (ESBL EC) in goose faeces varied broadly along the production cycle: in the first weeks, a sharp increase was observed in both farms, while later on A farm, the burden of ESBL EC remained steady until the end of the production cycle and on B farm the load dramatically decreased from 6 wk of age onward. An increase in the proportion of E. coli nal was observed on A farm shortly after the antibiotic administration. Our study shows that the dynamics of antibiotic-resistant E. coli in farmed geese are similar to the ones observed in broilers. However, the risk of the emergence of antibiotic-resistant commensal E. coli, might be mitigated by the adoption of good management practices, including prudent use of antibiotics., (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)

Background: Alpha-1 antitrypsin deficiency (AATD) is a hereditary disorder involving lungs, characterized by low serum concentration of the protein alpha-1 antitrypsin (AAT) also called proteinase inhibitor (PI). Asthma is common in AATD patients, but there are only few data on respiratory function in asthmatic patients with AATD., Objectives: The aim of the study was to evaluate lung function in asthmatic outpatients with mutation in the SERPINA1 gene coding for AAT versus asthmatic subjects without mutation., Methods: We performed the quantitative analysis of the serum concentration of AAT in 600 outpatients affected by mild to moderate asthma from the University Hospital of Parma, Italy. Fifty-seven of them underwent the genetic analysis subsequently; they were subdivided into mutated and non-mutated subjects. All the mutated patients had a heterozygous genotype, except 1 (PI*SS). We assessed the lung function through a flow-sensing spirometer and the small airway parameters through an impulse oscillometry system., Results: The values of forced vital capacity (% predicted) and those of the residual volume to total lung capacity ratio (%) were, respectively, lower and higher in patients mutated versus patients without mutation, showing a significantly greater air trapping (p = 0.014 and p = 0.017, respectively). Moreover, patients with mutation in comparison to patients without mutation showed lower forced expiratory volume in 3 s (% predicted) and forced expiratory volume in 6 s (L) spirometric values, reflecting a smaller airways contribution., Conclusions: In asthmatic patients, heterozygosity for AAT with PI*MZ and PI*MS genotypes was associated with small airway dysfunction and with lung air trapping., (© 2021 S. Karger AG, Basel.)

Previous studies suggested the suitability of the brackish-water serpulid (Ficopomatus enigmaticus) to be used as model organism for both marine and brackish waters monitoring, by the performance of sperm toxicity and larval development assays. The present study focused on larval development after the exposure of two F. enigmaticus populations (Mediterranean and Atlantic, collected in Italy and Portugal, respectively) to different trace elements (copper, mercury, arsenic, cadmium, and lead) at different concentrations. Results of larval development assays were presented as the percentage of abnormal developed larvae. The effect, measured in terms of EC 50 for all toxicants tested, showed that mercury was the most toxic metal for larvae of both populations. Specifically, the tested trace elements may be racked in the following order from the highest to the lowest toxicity: Mediterranean: mercury > copper > lead > arsenic > cadmium; Atlantic: mercury > copper > cadmium > arsenic > lead. Responses of both populations were similar for arsenic. Lead was the least toxic element for the Atlantic population, while cadmium showed the least toxicity for the Mediterranean population. These preliminary results demonstrate the sensitivity and suitability of the organisms to be used in ecotoxicological bioassays and monitoring protocols. Moreover, chemical analyses on soft tissues and calcareous tubes of collected test organisms and their sampling site water were performed, to identify and quantify the concentration of the tested trace elements in these 3 matrices. Populations exhibited less sensitivity to a certain element together with a relevantly higher concentration of the same element in soft tissues. This may indicate a certain resistance to particular contaminant toxic effects by organisms that tend to accumulate the same toxicant. This highlights the potential correlation between wild-caught test organisms' responses and a deep characterization of the sampling site to identify putative abnormalities or differences in model organism response during bioassay execution., (Copyright © 2020 Elsevier Inc. All rights reserved.)

Purpose: Recent studies from national registries have described changing patterns in epidemiology of acromegaly. Our retrospective study used administrative databases to estimate prevalence and incidence of acromegaly in the Piedmont Region, Italy., Methods: This study was conducted in Piedmont between 2012 and 2016 on administrative health databases for inpatients and outpatients of any age. Enrollees were included if claims suggestive of acromegaly were identified in at least two of the following databases: Drug Claims Registry, Hospital Information System, Co-payment Exemption Registry and Outpatient Specialist Service Information System., Results: 369 individuals (M = 146, F = 223) met our criteria. Overall incidence was 5.3 per million person years (95% CI 4.2-6.7), and prevalence was 83 cases per million inhabitants (95% CI 75-92). Mean age was 50.9 years. Both incidence and prevalence were slightly higher among women (rate ratio 1.08, prevalence ratio 1.43). Age-specific incidence was similar between sexes up to 39 years and diverged thereafter, with an increasing trend recorded among men. Prevalence was higher in women aged 40-79 years, and increased continuously up to 79 years in both sexes., Conclusions: This is the first population-based study conducted in Italy to estimate incidence and prevalence of acromegaly and results show a higher prevalence than previously reported. Although our algorithm requires proper validation, it constitutes a promising tool to describe the epidemiology of acromegaly.

Ficopomatus enigmaticus is a serpulid polychaete, reef-forming, dioecious gamete spawner throughout different seasons and in different salinity conditions. Due to these characteristics, its candidacy as a model organism to monitor both marine and brackish matrices was assessed. Marine sediments collected in a polluted area near the port of Ancona (Italy) were used as case study. Besides the chemical characterization of sediments, the larval development of F. enigmaticus was adopted as an assay for ecotoxicological assessment of sediments in addition to a regulatory bioassay battery with different organisms and endpoints. The quality of sediments was classified according to the Italian Ministerial Decree for sediment management (Ministerial Decree 173, 2016) by using the SEDI-QUAL-SOFT® (ver. 109.0) software developed by the Italian Environmental Protection Agency (ISPRA). The F. enigmaticus larval development assay showed a quite similar sensitivity to C. gigas larval development assays, indicating its potential use in a regulatory battery of bioassays., (Copyright © 2018 Elsevier Ltd. All rights reserved.)

Objectives: Fibromyalgia (FM) is defined as a severe, chronic, non-articular rheumatic condition characterised by widespread musculoskeletal pain, hyperalgesia and generalised tender points, in the absence of inflammatory or structural musculoskeletal abnormalities. Pain is the predominant symptom, allodynia and hyperalgesia are common signs. Extreme fatigue, impaired cognition and non-restorative sleeping difficulties coexist in addition to other somatic symptoms. Several studies suggest there is a meaningful relationship between FM and the psychological symptoms of depression and post-traumatic stress disorder (PTSD). PTSD is a mental disorder that can develop after a person has been exposed to a traumatic event, characterised by a specific set of symptoms including re-experiencing of the event, avoidance and numbing and arousal. The present study investigates the impact of lifetime potentially traumatic events, including losses, and of post-traumatic stress symptoms on the severity of illness in patients with fibromyalgia (FM)., Methods: Sixty-one patients with FM, diagnosed according to the American College of Rheumatology criteria, were consecutively enrolled at the Unit of Rheumatology, University of Pisa, Italy. Assessments included: the SCID-5 and the Trauma and Loss Spectrum Self-Report (TALS-SR) lifetime version., Results: 21.3% of the subjects (n=13) met the criteria for "partial" PTSD: 57.4% criterion B, 42.6% criterion C, 31.1 criterion D and 44.3% criterion E. Fibromyalgia patients without PTSD reported significantly lower scores in all domains compared to the patients with partial PTSD, the latter ones reporting significantly lower scores in all domains compared to full PTSD with the exception of domain I. In particular, these differences were noticeable in Domain VI and Domain VIII., Conclusions: The results of the study show that fibromyalgic patients with PTSD report more potentially traumatic events, avoidance symptoms, numbing, arousal, maladaptive coping and personality characteristics compared to patients with partial or without PTSD; these results could indicate that loss and/or trauma events represent a risk factor for the development of symptoms of FM in genetically predisposed individuals.

Coralline algae are calcareous algae able to build biogenic structures, thus playing a key-role as marine biodiversity promoters and calcium carbonate producers. The aim was to estimate the growth of Ellisolandia elongata under thermal stress. E. elongata were cultured for 2, 4 and 6 months under "natural" temperature (Tc) and increased temperature (Ti = Tc + 3 °C). In order to determine a possible culturing effect, growth in the field was also measured. For the first time, Alizarin Red S dye was used in high energy shallow water environments. Thallus linear extension was higher in the cultured specimens (Tc and Ti) compared to the field specimens. The carbonate mass in the field was higher than in Ti and Tc after 2, 4 months but decreased after 6 months. Partly unknown in situ environmental factors could have affected growth and calcification rates in the field while thermal adaptation could explain growth rates in the culturing experiment., (Copyright © 2015 Elsevier Ltd. All rights reserved.)

The reconstruction of triggering conditions, geomorphic effects, and damage produced by historical floods and debris flows significantly contributes to hazard assessment, allowing improved risk mitigation measures to be defined. Methods for the analysis of historical floods and debris flows vary greatly according to the type and quality of available data, which in turn are influenced by the time the events occurred. For floods and debris flows occurring in the Alps a few decades ago (between about 1950 and 1980), the documentation is usually better than for previous periods but, unlike events of most recent years, quantitative data are usually scanty and the description of the events does not aim to identify processes according to current terminology and classifications. The potential, and also the limitations of historical information available for the reconstruction of historical debris flows in the Alps have been explored by analyzing a high-magnitude debris flow that occurred on November 4, 1966 in the Chieppena Torrent (northeastern Italy). Reconstruction of the event was based on the use of written documentation, terrestrial and aerial photographs, and geomorphological maps. The analysis aimed to define the temporal development of phenomena, recognizing the type of flow processes and assessing some basic flow variables, such as volume, channel-debris yield rate, erosion depth, total distance traveled, and runout distance on the alluvial fan. The historical development of torrent hydraulic works, both before and after the debris flow of November 1966, was also analyzed with regard to the technical solutions adopted and their performance.

A total of 77 mentally retarded male inpatients residing in a psychiatric institution in northern Italy were screened for the presence of stool parasites, Entamoeba histolytica particularly. Parasitological stool examination showed Entamoeba spp. (E. histolytica and/or E. dispar) in 26 cases (33.7%). In vitro culture on Robinson's medium was positive in 16 cases (61.1%); in 11 cases we could stabilize and clone the isolates and proceed to electrophoretic assays. In all cases, patterns of pathogenic zymodemes were found (zymodeme II, 3 isolates; zymodeme XII, 4 isolates; zymodeme XIV, 4 isolates). All isolates were therefore identified as E. histolytica.