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World university rankings have had an impact on academic competition worldwide. The comparability of ranking results depends on how data is collected within each university. When data concepts are interpreted differently, data variety is introduced and ranking results cannot be used in a meaningful manner. In this case study, the effect of semantic harmonisation of the data concepts of the Times Higher Education World University Ranking is evaluated. Based on two independent initiatives, in Italy and in Belgium, the data and results of this ranking before and after interuniversity harmonisation of data collection are compared. This study demonstrates that, despite the data definitions provided by the ranking organisation, the data concepts 'academic staff' and 'students' are interpreted differently within each university. These differences can affect how universities are positioned relative to each other in ranking tables. A profound level of semantic harmonisation is then required to ensure semantically comparable data. [ABSTRACT FROM AUTHOR]

(1) Background: Within the framework of the European Interreg Italy–Switzerland B-ICE & Heritage project (2018–2022), this study originated from a three-year ethnobotanical survey in Valmalenco (Sondrio, Italy). Following a preliminary work published by our group, this research further explored the folk therapeutic use of Achillea erba-rotta subsp. moschata (Wulfen) I.Richardson (Asteraceae) for dyspepsia disorders, specifically its anti-inflammatory potential at a gastrointestinal level. (2) Methods: Semi-structured interviews were performed. The bitter taste was investigated through molecular docking software (PLANTS, GOLD), while the anti-inflammatory activity of the hydroethanolic extract, infusion, and decoction was evaluated based on the release of IL-8 and IL-6 after treatment with TNFα or Helicobacter pylori. The minimum inhibitory concentration and bacterial adhesion on the gastric epithelium were evaluated. (3) Results: In total, 401 respondents were interviewed. Molecular docking highlighted di-caffeoylquinic acids as the main compounds responsible for the interaction with bitter taste receptors. The moderate inhibition of IL-6 and IL-8 release was recorded, while, in the co-culture with H. pylori, stronger anti-inflammatory potential was expressed (29–45 μg/mL). The concentration-dependent inhibition of H. pylori growth was recorded (MIC = 100 μg/mL), with a significant anti-adhesive effect. (4) Conclusions: Confirming the folk tradition, the study emphasizes the species' potentiality for dyspepsia disorders. Future studies are needed to identify the components mostly responsible for the biological effects. [ABSTRACT FROM AUTHOR]

Recently it was shown, studying data acquired with in-situ measurements on the Gran Sasso mountain (Italy), for about ten years, by means of a high sensitivity transducer coupled to the free-end section of a stainless steel rod fixed by cement in a rock-drill hole 10 m high, about 2500 m above sea level, that Acoustic Emission (AE) can be affected by more than 90% False Acoustic Emission (FAE) of an electromagnetic origin. A very simple method to solve the problem of the discrimination between AE events due to elastic waves, from FAE signals, due to electromagnetic noise, both coming from the same "reception-point," is presented. The reliability of the obtained separation is confirmed also by the reported amplitude and time distribution of AE events, typical of fracture dynamics and those of FAE events, similar to those of noise. [ABSTRACT FROM AUTHOR]

Ethnopharmacological Relevance: Thistles species (Family: Compositae) are traditionally used in the Mediterranean area, particularly in Sardinia. They are usually gathered from the wild and used for both food and therapeutic purposes, including gastrointestinal disorders., Aim of the Study: This work aims to evaluate the anti-inflammatory activity of eight wild thistles from Sardinia, in an in vitro model of gastric inflammation, and to identify the major active compounds in the extracts., Materials and Methods: The hydro-alcoholic extract of the aerial part of each species was prepared. After the induction of inflammation by the addition of tumor necrosis factor-α (TNFα) (10ng/mL), AGS cells were treated with extracts/pure compounds under study. The inhibition of interleukin-8 (IL-8) release, IL-8 and NF-κB promoter activities and NF-κB nuclear translocation were evaluated. Extracts main components were identified by HPLC-PDA-MS/MS., Results: Only Onopordum horridum Viv. and Onopordum illyricum L. hydro-alcoholic extracts reduced, in a concentration-dependent fashion, the IL-8 release and promoter activity in human gastric epithelial cells AGS. The effect was partially due to the NF-κB pathway impairment. Onopordum hydro-alcoholic extracts were also chemically profiled, and caffeoylquinic acid derivatives were the main compounds identified in the extract. Further investigations showed that 3,5 dicaffeoylquinic acid highly inhibited IL-8 secretion in AGS cells (IC 50 0.65μM), thus suggesting that this compound contributed, at least in part, to the anti-inflammatory activity elicited by O. illyricum extracts., Conclusions: Our results suggest that Onopordum species may exert beneficial effects against gastric inflammatory diseases. Thus, these wild plants deserve further investigations as preventive or co-adjuvant agents in gastric diseases., (Copyright © 2017 Elsevier B.V. All rights reserved.)