1. Retinal Microvascular Alterations in Patients with Quiescent Posterior and Panuveitis Using Optical Coherence Tomography Angiography.
- Author
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Agarwal, Aniruddha, Bhatt, Sushil, Keshari, Shreya, Erckens, Roel J., Berendschot, Tos T. J. M., Webers, C. A. B., Agrawal, Rupesh, Bansal, Reema, and Gupta, Vishali
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OPTICAL coherence tomography , *CHOROID , *ANGIOGRAPHY , *FRACTAL dimensions , *RETINAL blood vessels , *FUNDUS oculi - Abstract
To quantify retinochoroidal vascular parameters using swept-source optical coherence tomography (SS-OCTA) in quiescent posterior and panuveitis. In this cross-sectional study, subjects with quiescent posterior and panuveitis underwent fundus imaging using SS-OCTA (DRI Triton®, Topcon, Japan). The metrics calculated were fractal dimension (FD), foveal avascular zone (FAZ) area, retinal vascularity index (capillary density index-CDI), and choroidal vascularity index (CVI). We included 38 eyes of 20 patients, 9 males aged 34.7 ± 10.5 years, 30 eyes of 30 age- and gender-matched healthy controls, 10 females aged 33.6 ± 8.5 years. Comparing patients with controls, we found a lower FD (p <.001), larger FAZ (p >.001), lower CDI in the superficial plexus (p =.019), and lower CVI (p <.001). We also found lower retinal and choroidal and thicknesses (p <.001 and p =.025, respectively). Patients with quiescent posterior and panuveitis have a significantly reduced retinochoroidal vascular density compared to healthy control subjects. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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