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Your search keyword '"Scleroderma, Localized drug therapy"' showing total 2 results
Start Over Descriptor "Scleroderma, Localized drug therapy" Region japan
2 results on '"Scleroderma, Localized drug therapy"'

1. Therapy of childhood generalized morphea: case reports and reviews of the literature of Japanese cases.

Author

Kawashima H, Watanabe C, Kashiwagi Y, Sato S, Ioi H, Sasamoto M, Takekuma K, Ookubo Y, Ooi T, and Hoshika A

Subjects
Child, Child, Preschool, Female, Humans, Japan, Scleroderma, Localized pathology, Dermatologic Agents therapeutic use, Glucocorticoids therapeutic use, Methotrexate therapeutic use, Prednisolone therapeutic use, Scleroderma, Localized drug therapy
Published
2006
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2. Unilateral generalized morphea in childhood.

Author

Nagai Y, Hattori T, and Ishikawa O

Subjects
Administration, Topical, Antibodies, Antinuclear analysis, Biopsy, Needle, Child, Follow-Up Studies, Humans, Immunohistochemistry, Japan, Leg, Male, Scleroderma, Localized diagnosis, Treatment Outcome, Adrenal Cortex Hormones administration & dosage, Scleroderma, Localized drug therapy, Scleroderma, Localized pathology
Abstract

We report a 6-year-old boy with unilateral generalized morphea distributing on the right side of his lower leg, trunk, and upper arm. A skin biopsy from the right thigh showed accumulation of thick collagen bundles extending from the middle dermis to the subcutaneous fat tissue. The levels of antinuclear antibodies, rheumatoid factor, and anti single-stranded DNA antibody were elevated. No severe deformity or functional disabilities were noted. With topical corticosteroid therapy, the sclerotic skin became gradually softer, and no progression of sclerosis has been noted for one year.

Published
2002
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