Search

Background: To predict possible enlargement of cerebral aneurysms with aging, we retrospectively analyzed aneurysm size in relation to patient age and aneurysm site., Methods: We included 1332 unruptured and 2362 ruptured aneurysms detected in patients from the Yamaguchi Prefecture, Japan, from 1995 to 2005., Results: Age-specific site distribution was not found in the unruptured aneurysms. In the ruptured aneurysms, the incidence of anterior communicating artery (AComA) aneurysms was higher than that of internal carotid posterior communicating (ICPC) artery aneurysms among the patients aged 40-49 years (32.6% versus 14.4%), whereas the difference was small among the elderly patients aged 70-79 years (25.8% versus 24.9%). In the AComA aneurysms, either in the unruptured or ruptured cases, no age-related change in size was found. In the ICPC aneurysms, either in the unruptured or in the ruptured cases, the size of the aneurysms 7 mm or larger increased with age., Conclusions: The sizes of AComA aneurysms may remain stable with aging. Therefore, the risk of rupture may be similar in young and elderly patients. Meanwhile, ICPC artery aneurysms may continue to grow throughout the patient's life, with an increasing risk of rupture., (Copyright © 2015 National Stroke Association. Published by Elsevier Inc. All rights reserved.)

Background: This study was a cerebral aneurysm registry study conducted in a region with few climatic differences. Based on data collected for over 20 years, seasonal variations and characteristics of subarachnoid hemorrhage (SAH) due to ruptured aneurysms were analyzed., Methods: This study included 5,007 patients in the Yamaguchi Prefecture with aneurysmal SAH between 1986 and 2005. Incidence rates by month, sex, age, severity, and aneurysm site were analyzed., Results: In women, seasonal variation was observed, in particular among those aged ≥50 years. Among those aged 50-69 years, the highest incidence was in October, and the nadir was in June (peak-to-trough ratio = 1.72). At age ≥70 years, this was slightly different, with the highest incidence in December and the nadir in July (peak-to-trough ratio = 1.48). However, there was no seasonal variation in men overall; it was limited to elderly men at age ≥70 years, with the highest incidence in January and the nadir in July (peak-to-trough ratio = 2.9). Aneurysm site and severity showed no relationship with seasonal variation., Conclusion: The present study shows seasonal variations in the onset of SAH. Seasonal variations in SAH differed depending on age and sex., (Copyright © 2013 S. Karger AG, Basel.)