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To evaluate the behavior of the advanced unbonded pre-stressed concrete containment vessel (UPCC\T) for one typical China nuclear power plant under Japan's March 11 earthquake, five nonlinear time history analysis and a nonlinear static analysis of a 1:10 scale UPCCV structure have been carried out with MSC.MARC finite element program. Comparisons between the analytical and experimental results demonstrated that the developed finite element model can predict the earthquake behavior of the UPCCV with fair accuracy. The responses of the 1:10 scale UPCCV subjected to the 11 March 2011 Japan earthquakes recorded at the MYG003 station with the peak ground acceleration (PGA) of 781 gal and at the MYG013 station with the PGA of 982 gal were predicted by the dynamic analysis. Finally, a static analysis was performed to seek the ultimate load carrying capacity for the 1:10 scale UPCCV. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effect of remote ischemic preconditioning (RIPC) on contrast-induced acute kidney injury (CI-AKI) in patients with chronic total occlusion (CTO) after percutaneous coronary intervention (PCI). Methods: A total of 282 patients undergoing PCI at Zhongda Hospital Affiliated to Southeast University between June 2017 and January 2019 were prospectively enrolled. The patients were randomly divided into RIPC group ( n =142) and control group ( n =140). CI-AKI was defined as an increase in level of cystatin C (CysC)≥10% above baseline at 24 h after contrast administration. Baseline characteristics and the incidence of CI-AKI were compared between the two groups. The multivariate logistic regression analysis was further used to analyze the independent risk factors of CI-AKI. Results: There were no significant differences in age, gender, smoking, hypertension, diabetes, stroke and old myocardial infarction, coronary artery bypass graft surgery, previous PCI history and laboratory test indicators, target vessel and pathological characteristics of CTO lesions, contrast agent dosage, J-CTO (Multicenter CTO Registry in Japan) score, SYNTAX (Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) score, PCI success rate and stent number between the two groups ( P >0.05). The incidence of CI-AKI was significantly lower (18.3% vs 29.3%, P =0.036) in RIPC group than that of control group. Multivariate logistic analysis found that creatinine [odds ratio ( OR )=1.018,95% CI : 1.006-1.030, P =0.003], CysC ( OR =5.200, 95% CI :2.714-9.963, P< 0.001),contrast agent dosage ( OR =1.013,95% CI : 1.007-1.019, P< 0.001) and J-CTO score ( OR =1.834, 95% CI : 1.145-2.939, P =0.012) were independent risk factors of CI-AKI. However, RIPC was an independent protective factor of CI-AKI ( OR =0.391, 95% CI : 0.199-0.765, P =0.006). Conclusion: RIPC before contrast agent administration prevents CI-AKI in CTO patients undergoing PCI.