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The article presents a study on high speed clinical data retrieval system that possesses event time sequence feature. It aims to depict a high-speed clinical data retrieving system from a century of data of operating hospital information system for research, evidence creation, and patient safety purposes. A total of 73,709,298 records within a century at Hamamatsu University Hospital were transmitted from HIS to retrieval system. The result shows that 112.22 seconds has been consumed during the search for listing patients prescribed with Pravastatin, and the searching conditions can be fixed to be more complex associated by Boolean operator.