Search

Objective: To determine correlation between duration of diabetes and severity of coronary artery disease (Gensini score) in patients, undergoing coronary angiography at tertiary care cardiac hospital. Methodology: A cross sectional study was conducted at Department of Cardiology, Tabba Heart Institute, Karachi from 17 September 2014 to 17th March 2015. All type 2 diabetic patients with 5 years or more duration of either gender with age 40 to 70 years, who had co-morbid like hypertension, smoking, and dyslipidemia been included in the study. The severity of coronary artery disease was found determined on Modified Gensini score correlate with duration of diabetes. The data was analyzed using SPSS version 17.0. Pearson correlation, univariate, and multiple linear regressions were applied. Results: Coronary artery disease was found more than double in men as in women. In female patients mean Gensini score was 63.43±45.25 whereas in male it was much higher (84.40±57.26). The mean Gensini score in patients of age =60 years was higher than patients' with age > 60 years. The male gender and duration of diabetics were found strong relation with the Gensini score. Conclusion: The duration of diabetic mellitus and male gender are positively correlated with the Modified Gensini score and appears to be the important determinants of severity of coronary artery disease (CAD). [ABSTRACT FROM AUTHOR]