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1. Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows.

Author

Saltzmann J, Xu Y, Gong YY, Lindahl J, Kersten S, Dänicke S, and Routledge MN

Subjects
Albumins, Animal Feed analysis, Animals, Cattle, Enzyme-Linked Immunosorbent Assay, Farms, Female, Kenya, Limit of Detection, Aflatoxin M1 analysis, Aflatoxins blood, Milk chemistry, Serum Albumin, Bovine analysis
Abstract

The aflatoxin (AF) albumin adduct is often used as a biomarker for aflatoxin exposure in humans. An ELISA method previously used for aflatoxin serum albumin in human blood was used to analyse bovine serum samples (n = 22) collected from dairy cattle during an aflatoxin mitigation study in Kenya. Albumin adduct data were compared with aflatoxin M 1 (AFM 1 ) levels in corresponding milk samples from these cows. The concentration ranged from < LOD to 487.9 pg/mL for AFM 1 and < LOD and 96.3 pg/mg for aflatoxin-albumin. This study indicates that aflatoxin-albumin adducts could be used as a measure of chronic aflatoxin exposure in dairy cattle.

Published
2020
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