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Objectives: To document the frequency of complications following Laparoscopic Sleeve gastrectomy in morbidly obese patients in population of Khyber Pakhtunkhwa province, Pakistan Material and Methods: This descriptive study was conducted at Lady Reading Hospital and Mohmand Medical Center, Peshawar from 1st May 2018 to 30th April 2019. All patients who underwent Laparoscopic Sleeve Gastrectomy were included in this study whether operated in public or private hospital. All patients were operated by a single surgeon. Data of complication was collected and analysed by using SPSS version 16.0. Results: A total of 22 patients enrolled with mean age of 36.2±8.1 years. Male to female ratio was 3.4:1. Mean pre-operative weight was 133.2±33.1 Kg and pre-operative Body Mass Index (BMI) was 47.6±7.5 kg/m2. Post-operative weight loss at one month was 10.79±15.6 kg, and post-operative BMI was 39.7±5.3 Kg/m2 at same point. Mean percentage of excess weight loss at one month was 38.9%. Post-operatively 2-patients had developed suture line bleed and 1-patient has developed pulmonary complication, while 1-patient needed invasive ventilation in post-operative period. 3-patients presented with rapid weight loss at one month follow up. Re-exploration and mortality was zero. Conclusions: Sleeve Gastrectomy is a safe and easy procedure to perform in a wide range of BMI's in obese patients with greater earlier benefits of significant weight loss. Consideration to a gastric bypass as a definitive procedure at a later date may be required in some patients. [ABSTRACT FROM AUTHOR]