13 results on '"Choi, Y. H."'
Search Results
2. The relationship between body fat mass and erectile dysfunction in Korean men: Hallym Aging Study.
- Author
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Cho YG, Song HJ, Lee SK, Jang SN, Jeong JY, Choi YH, Hong KS, Choi MG, Kang SH, Kang JH, Kim DH, and Caterson I
- Subjects
- Aged, Anthropometry, Body Mass Index, Electric Impedance, Erectile Dysfunction complications, Health Status, Health Surveys, Hemodynamics physiology, Humans, Korea epidemiology, Lipids blood, Logistic Models, Male, Middle Aged, Obesity complications, Obesity epidemiology, Odds Ratio, Surveys and Questionnaires, Adiposity physiology, Aging physiology, Erectile Dysfunction epidemiology, Erectile Dysfunction physiopathology
- Abstract
The aim of this study was to assess the relationship between body fat mass (BFM) and erectile dysfunction (ED) in Korean men. This study was a cross-sectional study using data on 208 men (the mean age=67.4+/-8.2). ED was diagnosed by the International Index of Erectile Function (IIEF)-5 and body fat percentage (BF%) was quantified with bioelectrical impedance. BF% was divided into quintiles (quintile 1: < or =20.5%, quintile 2: 20.6-23.2%, quintile 3: 23.3-25.8%, quintile 4: 25.9-28.8%, quintile 5: > or =28.9%). Using subjects with quintile 3 of BF% as reference, the adjusted odds ratios of subjects with the lowest quintile of BF% and with the highest quintile were 9.29 (95% CI: 2.29-37.72) and 4.99 (95% CI: 1.37-18.09), respectively. This study showed that BFM and ED had a U-shaped relationship in Korean men. These findings suggest that not only obesity but also a low BFM may be a risk factor of ED in Asians.
- Published
- 2009
- Full Text
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3. Hyperglycaemia, hypercholesterolaemia and the risk for developing gastric dysplasia.
- Author
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Jung MK, Jeon SW, Cho CM, Tak WY, Kweon YO, Kim SK, Choi YH, Bae HI, Lee JY, and Chung JM
- Subjects
- Biopsy, Blood Glucose metabolism, Body Mass Index, Cholesterol, LDL blood, Endoscopy, Gastrointestinal, Female, Follow-Up Studies, Humans, Hypercholesterolemia blood, Hypercholesterolemia epidemiology, Hyperglycemia blood, Hyperglycemia epidemiology, Incidence, Korea epidemiology, Male, Middle Aged, Obesity complications, Obesity epidemiology, Precancerous Conditions, Prognosis, Retrospective Studies, Risk Factors, Stomach Neoplasms epidemiology, Stomach Neoplasms pathology, Gastric Mucosa pathology, Hypercholesterolemia complications, Hyperglycemia complications, Stomach Neoplasms etiology
- Abstract
Background/goals: Gastric dysplasia is believed to be the penultimate stage of gastric carcinogenesis. Few studies have evaluated whether there is a relationship between such risk factors and gastric dysplasia. This case-control study was conducted to investigate the associations between obesity, serum glucose, lipids and gastric dysplasia., Study: Endoscopic findings and pathology specimens were reviewed from 1 July 1997 to 31 December 2006 in the Health Promotion Center. One hundred thirty patients have the dysplasia in the stomach during screening endoscopy. The same number of controls was evaluated and matched to the gastric dysplasia group for age and gender., Result: The univariate analysis showed that the dysplasia risk was slightly increased among persons with a higher low-density lipoprotein, lower high-density lipoprotein, impaired fasting glucose and higher total cholesterol. However, a higher body mass index and higher triglyceride level were not associated with the diagnosis of gastric dysplasia. In the multivariate-adjusted model, a higher low-density lipoprotein cholesterol and glucose were strongly associated with an increased risk of dysplasia compared to the controls. However, the body mass index, triglyceride and total cholesterol were not associated with the risk for dysplasia., Conclusion: Hyperglycaemia and low-density lipoprotein cholesterol appear to be associated with the risk for gastric dysplasia. Further epidemiologic studies including a large cohort of patients with gastric dysplasia and adenocarcinoma are needed to clarify the association of low-density lipoprotein cholesterol, serum glucose and gastric carcinogenesis.
- Published
- 2008
- Full Text
- View/download PDF
4. A promoter nucleotide variant of the dendritic cell-specific DCNP1 associates with serum IgE levels specific for dust mite allergens among the Korean asthmatics.
- Author
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Kim Y, Park CS, Shin HD, Choi JW, Cheong HS, Park BL, Choi YH, Jang AS, Park SW, Lee YM, Lee EJ, Park SG, Lee JY, Lee JK, Han BG, Oh B, and Kimm K
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Allergens, Antigen Presentation, Case-Control Studies, Child, Child, Preschool, Female, Gene Expression, Genetic Predisposition to Disease, Genotype, Humans, Korea, Male, Middle Aged, Polymorphism, Single Nucleotide, Antigens, Dermatophagoides immunology, Asthma genetics, Asthma immunology, Dendritic Cells immunology, Immunoglobulin E blood, Nuclear Proteins genetics, Promoter Regions, Genetic
- Abstract
Dendritic cells (DCs), the most abundant antigen-presenting cells in the lung, have been drawing attention for their roles in specific allergic responses to aeroallergens with support of Th lymphocytes, and in persistent inflammatory changes in allergic asthma. To identify genetic factors that may be involved in the asthma susceptibility and development of the disease phenotypes, we examined association of DC-specific DCNP1 polymorphisms with the disease risk. The case-control study revealed association of the nucleotide variants with serum immunoglobulin E (IgE) levels specific for Dermatophagoides farinae (Der f 1) and Dermatophagoides pteronyssinus (Der p 1), major aeroallergens of dust mites, among subjects with asthma. In particular, the T-allele-carrying genotype frequencies for one of the variants (c.-1289C>T) located in the promoter region were found increased in the asthmatic group with low levels of the mite-specific IgE (odds ratio (OR)=0.63 (0.48-0.83) for Der p 1). Results from functional analyses indicated that the promoter variant would affect the gene expression by modulating DNA-protein interaction. We propose that the genetic polymorphism of DCNP1 may influence production of specific IgE by altering DC functions in the mite allergen presenting and/or processing. The functional relevance of the genetic variation would provide an important insight into the genetic basis of allergic response to the mite antigens.
- Published
- 2007
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5. Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea.
- Author
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Chung DR, Lee SS, Lee HR, Kim HB, Choi HJ, Eom JS, Kim JS, Choi YH, Lee JS, Chung MH, Kim YS, Lee H, Lee MS, and Park CK
- Subjects
- Aged, Antigens, Bacterial immunology, Base Sequence, DNA Primers, Female, Humans, Klebsiella Infections microbiology, Klebsiella pneumoniae immunology, Korea epidemiology, Liver Abscess microbiology, Male, Middle Aged, Prospective Studies, Communicable Diseases, Emerging, Klebsiella Infections epidemiology, Klebsiella pneumoniae isolation & purification, Liver Abscess epidemiology
- Abstract
Objectives: The high incidence of invasive liver abscess caused by Klebsiella pneumoniae in Taiwan, contrasted with the rareness of this disease in Western countries, has aroused special interest. There have been few detailed reports from other Asian countries. To investigate a current epidemiology of K. pneumoniae liver abscess in Korea and to determine K serotype distribution in K. pneumoniae strains causing liver abscess, we performed a nationwide prospective study., Methods: Community-acquired, culture-proven liver abscess cases were enrolled between 2004 and 2005. Etiologies and clinical features were analyzed. K. pneumoniae isolates were serotyped according to K antigen. Meta-analysis was done to determine the time trend of the etiologies of liver abscess in Korea., Results: Out of 371 cases collected prospectively, 290 (78.2%) were caused by K. pneumoniae. Most K. pneumoniae liver abscesses were monomicrobial. Diabetes mellitus was the most common underlying disease (39.9%). Distant metastatic infections were frequently observed (8.7%). magA PCR revealed that 95 (59.4%) out of 160 K. pneumoniae isolates belonged to the K1 serotype., Conclusions: Our study indicates that K. pneumoniae has emerged as a major etiologic agent of liver abscess in Korea, and these emerging infections seem to be attributable to invasive K. pneumoniae strains with capsular K1 serotype.
- Published
- 2007
- Full Text
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6. Transfer of 137Cs to rice plants from various paddy soils contaminated under flooded conditions at different growth stages.
- Author
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Choi YH, Lim KM, Park HG, Park DW, Kang HS, and Lee HS
- Subjects
- Cesium Radioisotopes analysis, Korea, Oryza chemistry, Oryza growth & development, Plant Stems chemistry, Plant Stems metabolism, Power Plants, Radioactive Fallout, Seeds chemistry, Seeds metabolism, Soil Pollutants, Radioactive analysis, Cesium Radioisotopes metabolism, Oryza metabolism, Soil Pollutants, Radioactive metabolism
- Abstract
Soil blocks from 18 paddy fields around three Korean nuclear power plant sites were put into lysimeters. Greenhouse experiments were carried out to investigate the (137)Cs transfer from these paddy soils to rice plants for its deposition at different growth stages. A solution of (137)Cs was applied to the flooded lysimeters at 2-3 different stages. The applied (137)Cs was mixed with the topsoil only at the pre-transplanting application. The transfer was quantified with a transfer factor based on the unit-area deposition (TF(a), m(2)kg(-1)-dry). The TF(a) in the pre-transplanting application showed a remarkable variation with the soils. However, the differences in the mean values among the study sites were not statistically significant. The straw TF(a) was 2-3 times higher than the corresponding seed value. The early-tillering stage and booting stage applications resulted in a higher transfer than the pre-transplanting application by factors of, on an average, 2 and 16 for the straws, and 3 and 25 for the hulled seeds, respectively. The (137)Cs transfer was found to correlate negatively with the soil pH and positively with the organic matter content. Based on the present results, the representative (137)Cs TF(a) values for the rice are proposed for use in the whole of Korea for the deposition at three different growth stages.
- Published
- 2005
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7. A new triterpene lactone from the roots of Patrinia scabiosaefolia.
- Author
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Yang MY, Choi YH, Yeo H, and Kim J
- Subjects
- Korea, Lactones isolation & purification, Magnetic Resonance Spectroscopy, Plant Roots chemistry, Spectrophotometry, Infrared, Triterpenes isolation & purification, Lactones chemistry, Plants, Medicinal chemistry, Triterpenes chemistry, Valerianaceae chemistry
- Abstract
A new triterpene lactone named patrinolide A (1) has been isolated from the roots of Patrinia scabiosaefolia (Valerianaceae). Its structure was determined to be 11beta,21beta-dihydroxy-3-oxooleanan-28,13beta-olide on the basis of spectral analysis, including 2D-NMR techniques. Key words: Patrinia scabiosaefolia, Valerianaceae, Lactone, Patrinolide, 11beta,21beta-dihydroxy-3-oxooleanan-28,13beta-olide.
- Published
- 2001
- Full Text
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8. Isolation of a potent anti-MRSA sesquiterpenoid quinone from Ulmus davidiana var. japonica.
- Author
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Shin DY, Kim HS, Min KH, Hyun SS, Kim SA, Huh H, Choi EC, Choi YH, Kim J, Choi SH, Kim WB, and Suh YG
- Subjects
- Anti-Bacterial Agents isolation & purification, Bacteria drug effects, Korea, Microbial Sensitivity Tests, Plant Epidermis chemistry, Plant Roots chemistry, Quinones isolation & purification, Sesquiterpenes isolation & purification, Anti-Bacterial Agents pharmacology, Methicillin Resistance, Plants, Medicinal chemistry, Quinones pharmacology, Sesquiterpenes pharmacology, Staphylococcus aureus drug effects
- Abstract
A highly potent anti-MRSA sesquiterpenoid has been isolated from Ulmus davidiana var. japonica, which has been traditionally used to treat infectious diseases in Korea. This naturally occurring antibiotic was identified as mansonone F (1). This compound has been found to be highly active specifically against MRSA and showed an MIC range of 0.39-3.13 microg/ml which is comparable to that of vancomycin.
- Published
- 2000
- Full Text
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9. Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male population.
- Author
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Park JE, Lee WH, Hwang TH, Chu JA, Kim S, Choi YH, Kim JS, Kim DK, Lee SH, Hong KP, Seo JD, and Lee WR
- Subjects
- Adult, Age Distribution, Aged, Aged, 80 and over, Chi-Square Distribution, Comorbidity, Diabetes Mellitus epidemiology, Genotype, Humans, Hypertension epidemiology, Korea epidemiology, Male, Middle Aged, Myocardial Infarction epidemiology, Polymerase Chain Reaction, Risk Assessment, Statistics, Nonparametric, Aging physiology, Endothelium, Vascular enzymology, Myocardial Infarction physiopathology, Nitric Oxide Synthase genetics, Nitric Oxide Synthase metabolism, Polymorphism, Genetic
- Abstract
Objectives: The aging process affects responsiveness and other functions of endothelium and vascular smooth muscle cells, predisposing the old vessels to the development of atherosclerotic lesions. Endothelial nitric oxide synthase (ecNOS) gene polymorphisms were shown to affect the occurrence of acute myocardial infarction (AMI). We hypothesized that aging may affect the association between the ecNOS gene polymorphism and AMI., Methods: We investigated the age-related distribution of the ecNOS gene a/b polymorphism in 121 male AMI patients and 206 age-matched healthy male controls., Results: The aa, ab and bb genotypes were found in 1, 49 and 156 cases among the control subjects and 5, 23 and 93 cases among the AMI patients, respectively. There was a significant correlation between the ecNOS polymorphism and AMI (p = 0.045). When the correlation was analyzed by age, the significance remained only in the group below the age of 51 (p = 0.009). The proportion of smokers was increased in the young patients when compared to the old patients (p = 0.033), indicating that smoking also has greater effect on the younger population. The incidences of hypertension and diabetes mellitus, however, were similar in both populations., Conclusion: Our work provides the first evidence that links ecNOS polymorphism to the risk of AMI in relation to age. Young persons who smoke or have ecNOSaa genotype may have an increased risk of developing AMI. The functional as well as structural changes associated with aging in the vascular endothelium may mask the effect of the ecNOS polymorphism in the development of AMI in old persons.
- Published
- 2000
- Full Text
- View/download PDF
10. Seroprevalence of HTLV-I in Cheju Island, a Korean island adjacent to the endemic area of Japan.
- Author
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Kim JM, Chang KH, Choi YH, Song YG, Kang SM, Yoon TY, Choi JM, Park SY, and Lew DJ
- Subjects
- Adolescent, Adult, Age Distribution, Aged, Child, Child, Preschool, Endemic Diseases, Female, HTLV-I Infections transmission, Humans, Infant, Infant, Newborn, Japan epidemiology, Korea epidemiology, Male, Middle Aged, Seroepidemiologic Studies, Sex Distribution, HTLV-I Antibodies blood, HTLV-I Infections epidemiology, Human T-lymphotropic virus 1 immunology
- Published
- 1999
- Full Text
- View/download PDF
11. [Health status of elderly persons in Korea].
- Author
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Choi YH, Kim MS, Byon YS, and Won JS
- Subjects
- Analysis of Variance, Demography, Humans, Korea, Mental Health, Aged, Health Status
- Abstract
This Study was done to design and test an instrument to measure the health status of the elderly including physical, psychological and social dimensions. Data collection was done from July 18 to August 17, 1990. Subjects were 412 older persons in Korea. A convenience sample was used but the place of residence was stratified into large, medium and small city and rural areas. Participants located in Sudaemun-Gu, Mapo-Gu, and Kangnam-Gu, Seoul were interviewed by brained nursing students, and those in Chungju, Jonju, Chuncheon, and Jinju by professors of nursing colleges. Rural residents were interviewed by community health practitioners working in Kungsang-Buk-Do, Kyngsang-Nam-Do, Jonla Buk-Do, and Kyung Ki-Do. The tool developed for this study was a structured questionnaire based on previous literature and then tested for reliability and validity. This tool contained 20 physical health status items, 17 mental-emotional health status items and 38 social health status items. Physical health status items clustered in to six factors such as personal hygiene, activity, home management, digestive, sexual, sensory, and climatization functions. Mental-emotional health status items clustered into two factors, mental health and emotional health. Social health status items clustered into seven factors, grandparent, parent, spouse, friend, kinships, group member and religious role functions. Data analysis included percentage, average, S.D., t-test and ANOVA. The results of the analysis were as follows: 1. The tool measuring the health status of the elderly and developed for this research had a relatively high reliability indicated by a Cronbach = 0.97793. 2. Average score of the subjects physical health status was 4,054 in a 5 point likert scale, mental-emotional health status was 3.803, social health status was 2.939 and the total average was 3.521. The social status of the subjects was the lowest and the next was mental-emotional health status; physical health status was the highest. 3. Educational background, perceived health status, the amount of pocket money were related to physical and mental-emotional health status and family structure was related mental-emotional physical and social health status. Occupation was related to physical and mental-emotional status. Area of residence was related to mental-emotional and social status. Source of living in the expenses was related to physical and mental-emotional health status marital status to mental-emotional and social health status, and the number living in the home physical health status and religion to social health status.(ABSTRACT TRUNCATED AT 400 WORDS)
- Published
- 1990
- Full Text
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12. [Client's problem finding].
- Author
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Choi YH
- Subjects
- Humans, Korea, Nurse-Patient Relations, Nursing Care, Problem Solving
- Published
- 1978
13. [Administration in nursing education].
- Author
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Choi YH
- Subjects
- Humans, Korea, Education, Nursing, Schools, Nursing organization & administration
- Published
- 1985
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