1. Posterior segment involvement in Korean patients with HLA-B27-associated uveitis.
- Author
-
Kim SJ, Chung H, and Yu HG
- Subjects
- Adolescent, Adult, Aged, Azathioprine therapeutic use, Cyclosporine therapeutic use, Drug Therapy, Combination, Eye Diseases diagnosis, Eye Diseases drug therapy, Eye Diseases immunology, Female, Glucocorticoids therapeutic use, Humans, Immunosuppressive Agents therapeutic use, Korea, Macular Edema diagnosis, Macular Edema drug therapy, Macular Edema immunology, Male, Middle Aged, Prognosis, Retinal Vasculitis diagnosis, Retinal Vasculitis drug therapy, Retinal Vasculitis immunology, Retrospective Studies, Uveitis, Posterior drug therapy, Uveitis, Posterior immunology, Visual Acuity physiology, Vitreous Body drug effects, Vitreous Body immunology, Vitreous Body pathology, Young Adult, HLA-B27 Antigen immunology, Uveitis, Posterior diagnosis
- Abstract
Purpose: To compare clinical characteristics and visual prognosis between HLA-B27-associated uveitis patients with and without posterior segment involvement., Methods: Medical records of 78 patients with HLA-B27-associated uveitis were retrospectively analyzed., Results: Neither demographic nor clinical characteristics were associated with the presence of posterior segment involvement. In patients with posterior segment involvement, more aggressive therapeutic strategies, including immunomodulatory therapy, were frequently required. The rate of visual acuity 20/50 or worse was higher in patients with posterior involvement than in patients without posterior involvement., Conclusion: Patients with posterior segment involvement showed worse visual outcome than patients without posterior involvement.
- Published
- 2009
- Full Text
- View/download PDF