1. Intakes of plant foods, fibre and fat and risk of breast cancer - a prospective study in the Malmö Diet and Cancer cohort.
- Author
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Mattisson, I., Wirfält, E., Johansson, U., Gullberg, B., Olsson, H., and Berglund, G.
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BREAST cancer , *CANCER & nutrition , *WOMEN'S nutrition , *DIET in disease - Abstract
The objective of this study was to investigate prospectively the associations between intakes of plant foods, fibre and relative fat and risk of breast cancer in a subsample of 11?726 postmenopausal women in the Malmö Diet and Cancer cohort. Data were obtained by an interview-based diet history method, a structured questionnaire, anthropometrical measurements and national and regional cancer registries. During 89?602 person-years of follow-up, 342 incident cases were documented. Cox regression analysis examined breast cancer risks adjusted for potential confounders. High fibre intakes were associated with a lower risk of postmenopausal breast cancer, incidence rate ratio=0.58, 95% CI: 0.40, 0.84, for the highest quintile of fibre intake compared to the lowest quintile. The combination high fibre-low fat had the lowest risk when examining the effect in each cell of cross-classified tertiles of fibre and fat intakes. An interaction (P=0.049) was found between fibre- and fat-tertiles. There was no significant association between breast cancer risk and intakes of any of the plant food subgroups. These findings support the hypothesis that a dietary pattern characterised by high fibre and low fat intakes is associated with a lower risk of postmenopausal breast cancer.British Journal of Cancer (2004) 90, 122-127. doi:10.1038/sj.bjc.6601516 www.bjcancer.com [ABSTRACT FROM AUTHOR]
- Published
- 2004
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