9 results on '"Kales, Stefanos N."'
Search Results
2. Age-Related Decline in Cardiorespiratory Fitness among Career Firefighters: Modification by Physical Activity and Adiposity.
- Author
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Baur, Dorothee M., Christophi, Costas A., Francis Cook, E., and Kales, Stefanos N.
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PREVENTION of obesity , *ACADEMIC medical centers , *AGE distribution , *ANALYSIS of variance , *STATISTICAL correlation , *FIRE fighters , *REGRESSION analysis , *RESEARCH funding , *VASOMOTOR conditioning , *LOGISTIC regression analysis , *PHYSICAL activity , *DATA analysis software , *DESCRIPTIVE statistics - Abstract
Fire fighting is a very hazardous occupation, and strenuous fire duties require high levels of physical fitness. In the general adult population, cardiorespiratory fitness (CRF) declines with aging. We sought to investigate the effect of increasing age on CRF in male career firefighters as well as the modifying effects of physical activity and adiposity. We cross-sectionally examined 804 male career firefighters from two Midwestern states. CRF was determined from symptom-limited maximal treadmill exercise testing in metabolic equivalents (METS) following the Bruce protocol. Physical activity self-reports were extracted from responses to a health and lifestyle questionnaire. We found as expected that CRF declines with advancing age; however, the decline is greatly attenuated among leaner firefighters who report more physical activity. Furthermore, in a linear regression model including age, BMI, and variables describing physical activity behaviors, we could predict CRF (R2 = 0.6286). The total weekly duration of aerobic exercise as well as the duration of weight lifting sessions both had significant impacts on age-related decline. We conclude that firefighters are more likely to maintain the high levels of CRF needed to safely perform their duties if they engage in frequent exercise and maintain healthy weights. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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- View/download PDF
3. COVID-19 Vaccine Effectiveness in a Diverse Urban Health Care Worker Population.
- Author
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Iliaki E, Lan FY, Christophi CA, Guidotti G, Jobrack AD, Buley J, Osgood R, Bruno-Murtha LA, and Kales SN
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- Ethnicity psychology, Female, Humans, Male, Massachusetts epidemiology, Middle Aged, Risk Factors, SARS-CoV-2, Urban Population statistics & numerical data, Vaccination Hesitancy ethnology, Vaccination Hesitancy psychology, Vaccine Efficacy statistics & numerical data, COVID-19 epidemiology, COVID-19 prevention & control, COVID-19 Vaccines therapeutic use, Cultural Diversity, Health Personnel statistics & numerical data, Vaccination Coverage statistics & numerical data
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- 2021
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4. Evolving virulence? Decreasing COVID-19 complications among Massachusetts healthcare workers: a cohort study.
- Author
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Lan FY, Filler R, Mathew S, Iliaki E, Osgood R, Bruno-Murtha LA, and Kales SN
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- Adult, Biological Evolution, Cohort Studies, Female, Humans, Male, Massachusetts epidemiology, Middle Aged, Virulence, Young Adult, COVID-19 complications, COVID-19 virology, Health Personnel, SARS-CoV-2 genetics, SARS-CoV-2 pathogenicity
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- 2021
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- View/download PDF
5. Obesity and risk of LVH and ECG abnormalities in US firefighters.
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Soteriades ES, Targino MC, Talias MA, Hauser R, Kawachi I, Christiani DC, and Kales SN
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- Adult, Blood Pressure, Body Mass Index, Electrocardiography, Follow-Up Studies, Humans, Hypertrophy, Left Ventricular etiology, Incidence, Male, Massachusetts epidemiology, Middle Aged, Obesity complications, Prospective Studies, Young Adult, Firefighters statistics & numerical data, Hypertrophy, Left Ventricular epidemiology, Obesity epidemiology
- Abstract
Objective: To evaluate the association between obesity and electrocardiographic (ECG) abnormalities., Methods: We conducted a secondary analysis examining the association between body mass index and ECG abnormalities among Massachusetts' firefighters., Results: Overall, 276 firefighters had undergone ECG testing at baseline (1996/97) and follow-up (2000). The incidence of left ventricular hypertrophy (LVH) was 15 per 1000 person-years of follow-up. After adjusting for age, systolic and diastolic blood pressure, obese firefighters were about two times more likely to develop ECG-LVH (OR = 2.0; 95% CI, 0.6 to 6.6) and were 1.5 times more likely to develop ECG abnormalities (OR = 1.5; 95% CI, 0.6 to 3.9) at follow-up., Conclusions: Obese firefighters appear to have a higher risk of LVH and ECG abnormalities than normal-weight individuals. Our findings need further evaluation and may have important implications for occupational health policies and periodic medical evaluations.
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- 2011
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6. Firefighter heart presumption retirements in Massachusetts 1997-2004.
- Author
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Holder JD, Stallings LA, Peeples L, Burress JW, and Kales SN
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- Coronary Disease prevention & control, Fires prevention & control, Humans, Massachusetts, Middle Aged, Odds Ratio, Retrospective Studies, Coronary Disease epidemiology, Heart Diseases epidemiology, Insurance, Disability statistics & numerical data, Occupational Health, Retirement statistics & numerical data
- Abstract
Objective: "Heart Presumption" legislation is common throughout North America. We sought to study Massachusetts firefighters retiring with heart disability awards., Methods: The authors conducted a retrospective review of Massachusetts firefighters: 362 receiving Heart Presumption pensions (1997-2004) and a comparison group of 310 professionally active firefighters., Results: Of retirements, 77% were due to coronary heart disease and 23% for other cardiovascular conditions. Only 42% of the retirements were related to discrete on-duty events. Fire suppression (odds ratio = 51, 95% confidence interval = 12-223) and alarm response (odds ratio = 6.4, 95% confidence interval = 2.5-17) were associated with markedly higher risks of duty-related heart retirement events than nonemergency activities. Cardiovascular risk factor prevalence was high among all retiree subgroups and significantly greater than among control firefighters in almost all cases., Conclusions: Our study supports calls for improved cardiovascular prevention and risk reduction strategies among firefighters.
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- 2006
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7. Obesity and cardiovascular disease risk factors in firefighters: a prospective cohort study.
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Soteriades ES, Hauser R, Kawachi I, Liarokapis D, Christiani DC, and Kales SN
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- Adult, Body Mass Index, Cohort Studies, Exercise, Fires prevention & control, Humans, Male, Massachusetts epidemiology, Middle Aged, Risk Factors, Cardiovascular Diseases epidemiology, Obesity epidemiology, Occupations
- Abstract
Objective: Obesity, despite being a significant determinant of fitness for duty, is reaching epidemic levels in the workplace. Firefighters' fitness is important to their health and to public safety., Research Methods and Procedures: We examined the distribution of BMI and its association with major cardiovascular disease (CVD) risk factors in Massachusetts firefighters who underwent baseline (1996) and annual medical examinations through a statewide medical surveillance program over 5 years of follow-up. We also evaluated firefighters' weight change over time., Results: The mean BMI among 332 firefighters increased from 29 at baseline to 30 at the follow-up examination (2001), and the prevalence of obesity increased from 35% to 40%, respectively (p < 0.0001). In addition, the proportion of firefighters with extreme obesity increased 4-fold at follow-up (from 0.6% to 2.4%, p < 0.0001). Obese firefighters were more likely to have hypertension (p = 0.03) and low high-density lipoprotein-cholesterol (p = 0.01) at follow-up. Firefighters with extreme obesity had an average of 2.1 CVD risk factors (excluding obesity) in contrast to 1.5 CVD risk factors for normal-weight firefighters (p = 0.02). Finally, on average, normal-weight firefighters gained 1.1 pounds, whereas firefighters with BMI > or = 35 gained 1.9 pounds per year of active duty over 5 years of follow-up., Discussion: Obesity is a major concern among firefighters and shows worsening trends over time. Periodic medical evaluations coupled with exercise and dietary guidelines are needed to address this problem, which threatens firefighters' health and may jeopardize public safety.
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- 2005
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8. Prospective surveillance of hypertension in firefighters.
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Soteriades ES, Kales SN, Liarokapis D, and Christiani DC
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- Adult, Age Factors, Antihypertensive Agents therapeutic use, Blood Glucose metabolism, Blood Pressure physiology, Cholesterol blood, Cohort Studies, Coronary Artery Disease drug therapy, Coronary Artery Disease epidemiology, Coronary Artery Disease physiopathology, Diastole physiology, Female, Follow-Up Studies, Humans, Hyperlipidemias drug therapy, Hyperlipidemias epidemiology, Hyperlipidemias physiopathology, Hypertension drug therapy, Hypertension epidemiology, Hypolipidemic Agents therapeutic use, Male, Massachusetts epidemiology, Middle Aged, Prevalence, Prospective Studies, Risk Factors, Systole physiology, Treatment Outcome, Triglycerides blood, Fires prevention & control, Hypertension physiopathology, Population Surveillance
- Abstract
The authors evaluated blood pressure and antihypertensive medication use in 334 firefighters in an occupational medical surveillance program. Firefighters received written summaries of their examination results, including blood pressures, and were encouraged to see their personal physicians for any abnormal results. The mean age of the participants was 39 years, and the vast majority were men (n=330). The prevalence of hypertension was 20% at baseline (1996), 23% in 1998, and 23% in 2000. Among firefighters with high blood pressure readings, only 17%, 25%, and 22% were taking antihypertensive medications at the baseline, 1998, and 2000 examinations, respectively. Medical surveillance was effective in detecting hypertension in firefighters; however, after 4 years of follow-up, only 42% of hypertensives were receiving treatment with medications, including only 22% of firefighters with hypertensive readings. Overall, 74% of hypertensives were not adequately controlled. Possible reasons for low treatment rates may be the inadequate recognition among primary care physicians that mild hypertension is a significant risk factor for cardiovascular disease.
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- 2003
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9. Lipid profile of firefighters over time: opportunities for prevention.
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Soteriades ES, Kales SN, Liarokapis D, Christoudias SG, Tucker SA, and Christiani DC
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- Adult, Female, Follow-Up Studies, Humans, Hypercholesterolemia drug therapy, Hypercholesterolemia epidemiology, Hypertriglyceridemia drug therapy, Hypertriglyceridemia epidemiology, Male, Massachusetts epidemiology, Middle Aged, Risk Factors, Cardiovascular Diseases prevention & control, Hypercholesterolemia prevention & control, Hypertriglyceridemia prevention & control, Mass Screening, Occupational Health Services
- Abstract
Heart disease is the primary cause of on-duty deaths in firefighters, but little is known about their lipid profile. We evaluated the lipid profile in relation to other cardiovascular disease risk factors in 321 firefighters at a baseline examination. Prospective comparisons were performed for 285 firefighters, who were enrolled in a statewide medical surveillance program, and had complete follow-up data for 4 years. The average cholesterol level in firefighters declined from 224 mg/dL at baseline (1996-1997) to 214 mg/dL at the follow-up examination (P < 0.0001). Conversely, both obesity (body mass index > or = 30; 34% versus 40%, P = 0.008) and triglycerides (> or = 200 mg/dL; 27% versus 35%, P = 0.047) increased over time. The proportion of firefighters taking lipid-lowering medications increased from 3% at baseline to 12% at follow-up (P < 0.0001). Cholesterol levels declined significantly, and treatment rates for elevated cholesterol increased over time. Despite repeated examinations, a considerable number of firefighters had persistently elevated cholesterol, and only a minority were receiving adequate treatment.
- Published
- 2002
- Full Text
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