1. Hazardous waste and neurobehavioral effects: a developmental perspective.
- Author
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White RF, Feldman RG, Eviator II, Jabre JF, and Niles CA
- Subjects
- Adolescent, Adult, Age Factors, Aged, Central Nervous System growth & development, Central Nervous System physiopathology, Child, Hazardous Waste, Humans, Massachusetts, Middle Aged, Minnesota, Neuropsychological Tests, Ohio, Peripheral Nervous System growth & development, Peripheral Nervous System physiopathology, Poisoning diagnosis, United States, United States Environmental Protection Agency, Water Supply, Behavior drug effects, Central Nervous System drug effects, Developmental Disabilities chemically induced, Peripheral Nervous System drug effects, Trichloroethylene poisoning, Water Pollutants, Chemical poisoning
- Abstract
This paper summarizes the findings gleaned from detailed clinical examinations of three groups of residents who were exposed to trichloroethylene in well water. Also summarized are diagnostic findings for peripheral neuropathy. A detailed description of the neuropsychological test results is included, as well as a summary of domain-specific findings and diagnostic outcomes. A high rate of cognitive deficits of the type seen in patients with central nervous system dysfunction attributable to solvent exposure was seen. In addition, there was a clear developmental trend: subjects who were younger at the time of TCE exposure showed deficits in a larger variety of cognitive realms than did subjects who had already reached adulthood by the time of exposure. In particular, language deficits were seen in the younger, but not older, exposed subjects., (Copyright 1997 Academic Press.)
- Published
- 1997
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