Search

Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Cupressus pollen is one of the main causes of allergic respiratory disease in North America. In a previous study of pollen concentration in Monterrey, Cupressus occupied the 3rd place in frequency. Objective: To know the sensitization to Cupressus in patients treated at our center. Methods: We conducted an observational, cross-sectional and prospective study, with a questionnaire to assess potential exposure and allergic symptoms to pollen, skin tests with allergen extract of Cupressus 1:20 dilution, and skin tests with others 36 aeroallergens in our hospital. Results: We did Cupressus skin test in 256 patients (136 women), 130 younger than 18 years old and 126 adults. The skin test was positive in 39 patients (15.2%). Of the 36 aeroallergens tested, Cupressus occupied the 7th place in frequency. Of the 130 under 18 years, only 10 (7.7%) had a positive skin test. Among the other 129 adults, 29 (22.5%) had a positive skin test (p = 0.001). Patients with a positive skin test Cupressus had at least one positive skin test to other aeroallergen in 97% of cases (p ≤ 0.001). Conclusions: Cupressus sensitization in our study group was high (15.2%). The routine use of allergen extract of Cupressus should be considered in patients with respiratory allergy. However, it is necessary to determine precisely the prevalence of sensitization and its possible clinical implications. [ABSTRACT FROM AUTHOR]

Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: The frequency of sensitization to cats in patients with respiratory allergy may be as high as 60% and is a risk factor for developing cat allergy. Objective: To establish the frequency of sensitization to cats by environmental exposure and skin test to cat allergen Fel d 1 in patients with respiratory allergy. Methods: Prospective comparative cross-sectional study conducted from August to November 2009. One hundred ninety eight subjects divided into 2 groups (A group of 98 patients with respiratory allergy and a group of 100 healthy controls). Were included an epidemiological questionnaire and a clinical skin test to cat allergen Fel d 1 (1:20 w / v) by means of a epicutaneous prick (Prick-test) were applied. Results: The frequency of sensitization to cat measured by skin testing patients with respiratory allergy was 25% compared to 10% in healthy subjects (p = 0.004). In subjects with allergic rhinitis and asthma the frequency of sensitization to cat was 31%, whereas in subjects who had only allergic rhinitis was 22% (p = 0,416). The presence of symptoms after environmental exposure to cat in patients with respiratory allergy was 19%, in healthy subjects was 2% (P <0.001). The presence of cat at home in patients with respiratory allergy and positive to cat allergen on skin testing was 1%. Cat-sensitive patients had a frequency of sensitivity to other allergens such as D. pteronyssinus (80%); D.farinae (72%); Cynodon (52%); Amarantus, Salsola and Fraxinus (40%). Conclusion: The frequency of sensitization to cat allergen in patients with respiratory allergy was 25%, similar to that reported on other series. [ABSTRACT FROM AUTHOR]

Objective: Report the prevalence and severity of the most common allergic diseases in children living in Monterrey, México., Methods: Cross-sectional multi-center survey on the most common allergic diseases, completed by parents of 6-7-year-old children and by 13-14- year-old adolescents in the Monterrey metropolitan area, between January 2018 and December 2019., Results: A total of 3,044 questionnaires were eligible for the analysis. Among children between 6-7 years old, 30.2% (n = 143/473) presented wheezing at any time in their life; with a higher prevalence in the male population. In the adolescent group, 26.4% reported having experienced wheezing at some point in their life, with a slight predominance in the female group (54.9%)., Conclusions: Knowing the prevalence of allergic diseases in our population gives us tools to generate strategies that allow us to provide the best quality healthcare to our patients., Competing Interests: The authors declare no conflicts of interest.

Objective: The aim of this pilot study was to assess the efficacy of doxofylline as an ICS-sparing agent in the treatment of Mexican children with asthma., Methods: 10-week, open-label, crossover, pilot study, we examined the steroid-sparing effect of doxofylline in Mexican children with asthma. Patients aged 6-16 years treated with inhaled corticosteroids (ICS) for at least 8 wk before enrollment were divided randomly into two groups at the baseline visit. Group A ( n  = 31) received doxofylline (18 mg/kg/day) plus standard-dose budesonide (D + SDB) for the first 4-week period followed by doxofylline plus reduced-dose budesonide (D + RDB) for the second 4-week period. Group B ( n  = 30) received D + RDB followed by D + SDB. Clinical outcomes assessed included lung function (forced expiratory volume; in 1 s, FEV1), fractional exhaled nitric oxide (FeNO), asthma control, number of exacerbations and use of rescue medication (salbutamol)., Results: It was shown that combined use of doxofylline and ICS may allow children with asthma to reduce their daily dose of ICS while maintaining lung function and improving asthma control ( p  = 0.008). There were few asthma exacerbations and only one patient required treatment with systemic corticosteroids. Rescue medication use decreased significantly in patients receiving D + SDB during the first 4-week period., Conclusions: Our results suggest that doxofylline may be a steroid-sparing treatment in asthma, but longer-term, controlled studies are needed to confirm these observations.

Objective: To compare whether adolescents who are exposed to truck smoke have a higher prevalence of asthma symptomatology versus those who are not exposed., Methods: A cross-sectional, descriptive, and comparative study. Adolescents aged 13 and 14 years were included and completed a self-report questionnaire. Subjects were selected following the same methodology as in ISAAC phase III. They underwent an epidemiological survey for the presence of symptoms. Ex- posure to truck smoke was defined as passing trucks most of the day as perceived by the patient. The distribution was assessed with the Kolmogorov-Smirnov test. Comparisons with Chi-square or Student's t-test, as appropriate. A value of p³0.05 was considered statistically significant., Results: A total of 492 patients were included. The demographic variables can be seen in Table 1. When performing the association between the groups of ad- olescents with asthma exposed to truck smoke, a significant difference was found in the prevalence of respiratory symptomatology and asthma (26.0% vs 9.6%, p=0.000) (Table 1)., Conclusions: Adolescent patients with asthma who are exposed to truck smoke demonstrated a significant difference in the presence of respiratory symptom- atology and asthma compared to patients without exposure., (Este obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial 4.0 Internacional.)

Background: Chronic urticaria (CU) manifests itself with hives and sometimes angioedema. Physical and social discomfort worsens patient quality of life. CU has an important impact on patients' economy., Objective: To evaluate the relationship of quality of life (QoL) with economic burden and chronic urticaria control of in patients treated at our center., Methods: Cross-sectional, descriptive, observational study. We included CU-diagnosed adult patients. The CU-Q2oL and UCT questionnaires in Spanish and the economic burden and comorbidities questionnaire developed by our center were applied. A sample size of 36 patients was calculated., Results: 36 patients were included, out of which 58.3% were females. Mean age was 39.9 ± 15.6 years. Regarding QoL, 66.7% of patients reported being "A little" affected, 25% "Somewhat" and 8.3% "A lot", and its relationship with monthly income yielded a p-value of 0.017. 38.9% of patients reported having a monthly income of less than $ 5000 pesos. When disease control was compared with the CU-Q2oL, a significant difference was obtained for questions concerning itching., Conclusion: There was association between the quality of life of patients with chronic urticaria and monthly income, the lower the income, the more will the quality of life be affected. Furthermore, greater CU control was observed to reduce the negative effects on quality of life caused by itching.

Background: Food allergy is an abnormal immunologic response to food allergens. Prevalence varies between 2% and 8%, although it could vary according to age and ethnicity. Clinical manifestations are diverse among systems. There is few information about this issue., Objective: To know epidemiologic features in patients with food allergy attended at Monterrey University Hospital., Patients and Method: An observational, transversal and retrospective study was done, identifying 60 patients with food allergy diagnosis attended in our service from June 1, 2007 to December 31, 2008. Epidemiologic and clinical data were registered. Data was processed with statistical program SPSS v16.0 for windows with descriptive statistic., Results: The frequency of food allergy reported in first time medical consultation was 2.67%, 51% of the patients were under 5 years of age. Most frequent foods were: dairy products, egg, fish, shrimp, beans, soy, chili, mango, cacao, and strawberry. Main symptoms were cutaneous in 58% of the patients, followed by gastrointestinal and respiratory. Most common concomitant diseases were: urticarial angioedema (38%), allergic rhinitis (20%), atopic dermatitis (15%), and asthma (6.6%). Average time for diagnosis was 1.45 years., Conclusions: Most common foods with positive Prick test results were dairy products, egg and fish. Despite the variability of the clinical manifestations, cutaneous and gastrointestinal manifestations are the most frequent; however, the diagnosis depends on the suspicion as well.

Background: The reported prevalence of allergic systemic reactions to hymenoptera venom occur in up to 3.3% and large local reactions occur in 17% in the general population., Objective: To investigate the prevalence of hymenoptera sting allergy in a group of veterinary medicine students from Monterrey, Nuevo Leon, Mexico., Participants and Methods: A transverse and observational study was done with 64 students of veterinary medicine. We conducted a questionnaire about the students' history of insect allergy and atopy. Skin test with allergenic extracts of bee and ant were practiced to all subjects. We performed aeroallergen skin prick test to the subjets with suspected atopy., Results: Students age ranged from 17 to 25 years (mean 20.2) and 37 were males. Twenty students (31.3%) had clinical history of atopy and positive skin tests to aeroallergens. On the other hand, 5 students (7.8%), including 2 atopic, had suffered large local reactions, but none of them had suffered systemic reactions. Bee and ant skin tests were positive in 15.6% and 31.3% of the students respectively. There was no difference in the prevalence of hymenoptera allergy between atopic and non atopic subjects (p < 0.05). Further, the frequency of atopy in subjects with positive skin tests for bee and ant was 50%., Conclusion: The prevalence of large local reactions and hymenoptera sensitization found in this group was similar to that found in other epidemiologic studies.

Background: In 1998 the economic burden of asthma in the United States was estimated in 12.7 billion dollars. In Mexico the annual direct costs for asthma could be approximately from 32 to 35 million dollars., Objective: To estimate the healthcare costs in asthmatic children in the Northeast of Mexico., Material and Methods: A descriptive cross-sectional study was performed. We applied a questionnaire to the parents of 60 asthmatic children. They attended to a conference about asthma and allergy illnesses. In this questionnaire the parents answered some questions that provided us information about expenditures because of the treatment of their children with asthma during the last year., Results: Fifty-six questionnaires were answered correctly. The mean age of children was 10.8 +/- 2.5 years and 64.3% of them were males. The annual costs reported by patient were < or = 225 USD for medical consultation (76.8%) and < or = 134 USD for immunotherapy (81.6%). On the other hand, the costs for emergency department visits and hospitalization were < or = 45 USD and < or = 180 USD by each event respectively., Conclusions: The costs of asthma treatment in children are considerable and cause a huge impact in the family economy. It is necessary further research in bigger groups and doing comparative studies among different groups will help clarify the extent of the economic burden of asthma in Mexico.

Background: Drug adverse reactions are a common cause of morbidity and they constitute an important challenge in medical practice. The allergic reactions represent only a small proportion of all the drug adverse reactions and although their real prevalence is unknown, some estimated numbers have been suggested. It seems that atopia is not a risk factor for the development of this kind of reactions., Patients and Methods: A cross-sectional descriptive study was performed to assess the prevalence of drug allergy in asthmatic children of the northeast of Mexico that attend summer camps. We investigated the history of drug adverse reactions and their clinical features in 90 atopic asthmatic patients from 5 to 15 years old which were evaluated trough a questionnaire that was completed by their parents., Results: Eight of the 90 evaluated patients (8.8%) had history of adverse reactions to some drug. The drugs involved in that reactions were: penicillin in four patients (50%), aspirin in 2 (25%), trimethoprim and sulfamethoxazole in one (12.5%) and metamizole sodium in one (12.5%). The most common administration route was oral. In all of the cases the diagnosis was made on clinical basis. One of the patients had suffered from anaphylaxis, but in the other seven, urticaria was the unique clinical manifestation of the reaction. In all of the affected patients, the reactions were totally resolved in less than 48 hours., Conclusions: The prevalence of drug allergy in this group was similar to that reported in general population. Penicillin was the most common involved drug and urticaria was the most frequent clinical manifestation.