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Copyright of Revista Mexicana de Biodiversidad is the property of Universidad Nacional Autonoma de Mexico, Instituto de Biologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVES:Studies suggest that altered immune activation, manifested by an imbalance in anti- and pro-inflammatory cytokine levels, exists in a subgroup of irritable bowel syndrome (IBS) patients. However, similar studies have not been conducted in Latin populations. The objective of this study was to measure serum levels of interleukin (IL)-10 and tumor necrosis factor (TNF)-α in subjects fulfilling symptom criteria for IBS and controls.METHODS:Volunteers (n=178) from a university population in Mexico City, participated in the study. Of the sample, 34.8% met Rome II criteria for IBS and 65.2% were designated as controls. Serum cytokines were measured by enzyme-linked immunoabsorbent assay. Analysis of covariance models were used to test main effects between gender, IBS symptoms, and bowel habit subtype to explain the cytokine serum levels. Statistical models were tested using body mass index as a covariate.RESULTS:IL-10 levels were significantly lower in IBS vs. controls (mean (95% confidence interval): 15.6 (14.8, 16.3) vs. 18.6 (17.9, 19.4) pg/ml, P<0.001), while TNF-α levels were higher in IBS (20.9 (19.1, 23.0) vs. 17.9 (16.7, 19.3) pg/ml, P=0.010). IBS and female gender were independent predictors for IL-10 (P<0.05). In contrast, female gender was an independent predictor for TNF-α. In addition, women with IBS-D had the lowest IL-10 (P<0.001) and highest TNF-α (P=0.021) vs. other subtypes.CONCLUSIONS:The lower serum IL-10 in our subjects fulfilling IBS Rome II symptom criteria suggests an altered immune regulation. Further studies are needed to elucidate if a lower serum IL-10 may be useful as a biomarker for IBS in the Mexican population, especially for women with IBS-D. [ABSTRACT FROM AUTHOR]

Background: Potentially inappropriate prescription (PIP) constitutes a risk for the development of adverse effects of a drug that outweigh its benefits, which can be considered inappropriate medication use., Objective: To describe the prevalence of PIP in geriatric patients hospitalized at the internal medicine department of a referral hospital in Mexico., Material and Methods: Cross-sectional, descriptive design, with simple allocation of medical records from patients older than 65 years hospitalized between January 2016 and August 2017. The STOPP/START criteria were applied to identify the number of PIPs, the number of prescribed medications, number and type of comorbidities, as well as days of hospital stay., Results: A prevalence of PIP of 73.3% was identified, with main comorbidities being hypertension and type 2 diabetes mellitus. A total of 1,885 prescribed medications were quantified; mean hospital stay was 6.3 days., Conclusions: A high prevalence of PIP was identified in hospitalized geriatric patients, hence the importance of applying the STOPP/START criteria and of the role of the pharmacist for validating the prescription prior to drug administration., (Copyright: © 2023 Permanyer.)

The whale shark is an endangered species that usually feeds in coastal areas of highly productive seas such as the Gulf of California, Mexico. This study aims to describe the effect of sea surface temperature, chlorophyll a, bathymetry and slope on the habitat suitability of whale sharks in three important aggregation sites of the Gulf of California. A total of 2396 records of occurrence of whale sharks were obtained from international databases and scientific literature between 1996 and 2018. These records were used for the creation of a species distribution model using MaxEnt for each of the three aggregation sites. The concentration of chlorophyll a explained 71% of the habitat suitability, followed by bathymetry and slope with a combined 17%, and sea surface temperature constituting 10% of the model. Habitat suitability was related to areas where nontargeted fisheries may impact whale sharks through bycatch, entanglement and ship strikes. The implications for the conservation of whale sharks should be considered for management decisions in terms of marine protected areas, fishing refugees or bans, and other regulations regarding fisheries activities., (© 2020 Fisheries Society of the British Isles.)

Objective: To evaluate clinical evolution of pediatric patients diagnosed with glioblastoma multiforme (GBM) at Hospital Infantil de México Federico Gómez., Methods: Cases of patients treated from January to May, 2007, were included in this study. Variables analyzed were: age, diagnosis, size of tumor, histopathological description, degree of resection, time of stay in hospital, complications and outcome using Pearson's chi-squared test and logistic regression., Conclusion: Sixteen patients were identified. Mean age of presentation was 8.8. An increased frequency of complications was observed in younger patients and longer survival rates in patients with greater resections; main mode of presentation was directly related to intracranial hypertension; size of tumor was not related to evolution or outcome. Modern histological classifications especially designed for children are deemed necessary to accurately diagnose GBM.

Introduction: The utilisation of pesticides in the large cities has been increased. Exist few studies that determine the damage in the respiratory appliance., Objective: Determined on a healthy population of Mexico City with two known products used for the control of the insecticides in household, with the main objective to determine the clinical and functional manifestations that its use implies., Material and Methods: They were included 70 sound volunteers with residence in the City of Mexico that lived in apartments with 100 square meters of construction, tobacco negative and without previous antecedents of cardiovascular disease, without acute infectious process. They were split into 2 groups one that inhaled pesticides for combustion and the group b in electric form, In them I accomplished study espirometric to the beginning and during 3 exposed hours. The analysis by T Student., Results: In group A was observed a meaningful difference of 0.01 in the first hour and of p < 0.028 in the second and third hours, with collateral effects as irritation eyes (74%) disnea (57%) cough (43%) and headaches (28%). Group B with a small difference of the VEF-1 in the first hour p < 0.03 and without differences on the following hours. We haven't observed secondary effects according to this group. The analysis en both group we have only differences in the first hours with p < 0.004., Conclusion: The exposition to pesticides our group for combustion produces a lot of clinical and functional alterations than the electric pesticides.