Search

Researchers at the National Polytechnic Institute in Mexico City have conducted a study on the neuroprotective effects of the hormones prolactin and 17 beta-estradiol (E2) on hippocampal injury and long-term memory deficit. The study found that both hormones individually prevented memory deficits and provided neuroprotection against excitotoxicity in the hippocampus. However, the combined treatment of prolactin and E2 was found to be more effective in improving memory and neuronal survival. These findings suggest a synergistic effect between prolactin and E2 in producing behavioral, proliferative, and neuroprotective effects in the hippocampus. [Extracted from the article]

A research report from the Department of Reproductive Biology discusses the role of c-Src kinase in promoting metastasis in breast cancer. The study found that estradiol (E-2) enhances the epithelial-to-mesenchymal transition (EMT) and migration of breast cancer cells that express estrogen receptor alpha (ER alpha). The activation of c-Src kinase by E-2 leads to changes in the localization of proteins involved in cell adhesion, ultimately increasing the migratory and invasive capacities of the cells. The findings suggest that c-Src kinase could be a potential therapeutic target for breast cancer treatment. [Extracted from the article]

Keywords: Mexico City; Mexico; North and Central America; Corpus Luteum Hormones; Estradiol Congeners; Gonadal Hormones; Health and Medicine; Progesterone EN Mexico City Mexico North and Central America Corpus Luteum Hormones Estradiol Congeners Gonadal Hormones Health and Medicine Progesterone 475 475 1 09/25/23 20230929 NES 230929 2023 SEP 29 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on Hormones - Corpus Luteum Hormones have been presented. Mexico City, Mexico, North and Central America, Corpus Luteum Hormones, Estradiol Congeners, Gonadal Hormones, Health and Medicine, Progesterone. [Extracted from the article]