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Hops (Humulus lupulus L.) and figs (Ficus carica) are two kinds of edible plants widelydistributed in Xinjiang. Hops is cultivated worldwide for commercial use as raw material in the brewing in dustry since it adds bitterness and aromatic flavors to the beer. These characteristics are mainly ascribed to hop's soft resins. However, its soft resin components are rarely studied and the structures of their derivatives remain unclear. Figs is an Asian species of flowering plant belonging to the genus Ficus of the family Moracese, native to Western Asia and the Middle East. Its fruits, usually knownas common figs, have been consumed as a very popular health promoting fruit worldwide since ancient times. To investigate the potential health-promoting chemical constituents of two edible pants, a phytochemical study on its fruits were therefore carried out, which might provide deeper insight into material basis of them. These two plants were collected, dried, powdered, and extracted with ethanol. The extraction solutions were combined and concentrated to yield a crude extract, whichwas suspended in water and then partition successively with petroleum ether, chloroform, ethyl acetate, and butanol extract, respectively. Different fraction was isolated and purified by silica gel, RP-18 gel, Sephadex LH-20 column chromatographies and semipreparatives HPLC to afford more than 200 compounds. The racemates were separated by chiral column. Their planner structures wereestablished based on the comprehensive investigation of (1D, 2D) NMR and HR-ESI-MS data. The absolute configurations of compounds were determined by comparing chemical chemical of their chiral carbon atoms and the experimental ECD and calcualted ones. In total, more than 200 compounds were isolated from two edible plant. The irrepresentative structures are as shown in Figure 1. The anti-inflammatory effects andanti-microbial activities of these isolated prenylated compounds were test. Some of these compounds show good activity and are superior to positive control. Acknowledgment: This research was funded by the Natural Science Program (No. 2020D01B56), the West Light Foundation of the Chinese Academy of Sciences (No. 2019-XBQNXZ-B-011), the youth Innovation Promotion Association CAS. [ABSTRACT FROM AUTHOR]